US3926809A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Multi-column fractionator
Assignee: Individual
•
Filing: 1973-10-10
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Granted: 1975-12-16
•
Expires: 1993-10-10
Abstract
Abstract A chromatography apparatus for the simultaneous fractionation of two, three and four different mixtures of nucleotides, each on a separate ion-exchange column, using a stepwise elution procedure. Each elution solvent, used in a stepwise elution procedure, is forced by air pressure from a single interchangeable reservoir flask on to and through each of two, three or four chromatography columns at the same moment after having been dispersed equally by a multi-valve control.
Inventors
- 👤 Roosevelt J Jones
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-27 05:31
CPC Classifications
G; G01; G01N; G01N30/00; G01N30/02; G01N30/26; G01N30/38; G01N30/46; G01N30/466; G01N30/80; G01N30/96
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
133 words
IN AN APPARATUS FOR ANALYZING SAMPLES OF NUCLEOTIDES USING A PLURALITY OF CHROMATOGRAPIC COLUMNS THE IMPROVEMMENT 4 INTERCHANGEABLE RESERVOIR MEANS, EACH SAID RESERVOIR HOLDING AN ELUTION SOLVENT OF A DIFFERENT PH CONCENTRATION; A SET OF FOUR CHROMATOGRAPHIC COLUMNS; A FOUR-WAY MULTIVALVE CONTROL WHICH DISPERSE EQUALLY ELUTION SOLVENT OF THE SAME PH CONCENTRATION ON TO EACH OF SAID FOUR CHROMATOGRAPHY COLUMNS AT THE SAME MOMENT; SAID COLUMNS CONTAINING ION-EXCHANGE RESIN CAPABLE OF SEPARATING A MICTURE OF NUCLEOTIDES; MEANS CONNECTING SAID VALVE BETWEEN SAID RESERVOIR AND SAID COLUMNS; A BURETTE FOR MEASURING ELUENT VOLUME COLLECTED FROM EACH OF SAID CHROMATOGRAPHIC COLUMNS; A SET OF COLLECTING TUBES HELD UPRIGHT IN TEST TUBE HOLDER MEANS; PRESSURE MEANS CONNECTED TO SAID RESERVOIR MEANS FOR FORCING SAID ELUTION SOLVENT THROUGH SAID VALVE MEANS AND INTO EACH OF SAID COLUMNS.
Claim 2
Dependent Claim
133 words
IN AN APPARATUS FOR ANALYZING SAMPLES OF NUCLEOTIDES USING A PLURALITY OF CHROMATOGRAPIC COLUMNS THE IMPROVEMMENT 4 INTERCHANGEABLE RESERVOIR MEANS, EACH SAID RESERVOIR HOLDING AN ELUTION SOLVENT OF A DIFFERENT PH CONCENTRATION; A SET OF FOUR CHROMATOGRAPHIC COLUMNS; A FOUR-WAY MULTIVALVE CONTROL WHICH DISPERSE EQUALLY ELUTION SOLVENT OF THE SAME PH CONCENTRATION ON TO EACH OF SAID FOUR CHROMATOGRAPHY COLUMNS AT THE SAME MOMENT; SAID COLUMNS CONTAINING ION-EXCHANGE RESIN CAPABLE OF SEPARATING A MICTURE OF NUCLEOTIDES; MEANS CONNECTING SAID VALVE BETWEEN SAID RESERVOIR AND SAID COLUMNS; A BURETTE FOR MEASURING ELUENT VOLUME COLLECTED FROM EACH OF SAID CHROMATOGRAPHIC COLUMNS; A SET OF COLLECTING TUBES HELD UPRIGHT IN TEST TUBE HOLDER MEANS; PRESSURE MEANS CONNECTED TO SAID RESERVOIR MEANS FOR FORCING SAID ELUTION SOLVENT THROUGH SAID VALVE MEANS AND INTO EACH OF SAID COLUMNS.
Claim 3
Dependent Claim
18 words
The apparatus of claim 1 wherein said reservoir means consist of wide mouth jar, clamp and rubber stopper.
Claim 4
Dependent Claim
16 words
The apparatus of claim 2 further including said columns, jar and tubes being constructed of glass.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-12-15 | 1979-06-16 | 1979-12-16 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-12-15 | 1983-06-16 | 1983-12-16 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-12-15 | 1987-06-16 | 1987-12-16 | $7700.00 | Window Closed / Lapsed |