Patent US4602024A successfully refreshed from Google Patents.
US4602024A
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Substituted trifluoromethylphenyltetrahydropyridines having a cyano substituent and an anorectic activity, a process for preparing same and pharmaceutical compositions
Assignee: Elf Sanofi SA
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Filing: 1984-07-16
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Granted: 1986-07-22
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Expires: 2004-07-16
Abstract
Abstract The invention relates to 4-(-3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridines of formula <IMAGE> in which R represents a cyano, acetyl or cycloalkyl group of from 3 to 7 carbon atoms and Alk represents a straight or branched alkylene of from 1 to 4 carbon atoms, as well as to the salts thereof, having an anorectic activity, to a process for preparing same and to pharmaceutical compositions containing said compounds, useful in the treatment of obesity.
Inventors
- 👤 Dino Nisato
- 👤 Emilio Crisafulli
- 👤 Alberto Bianchetti
- 👤 Paolo Carminati
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 18:07
CPC Classifications
C; C07; C07D; C07D211/00; C07D211/04; C07D211/68; C07D211/70; A; A61; A61P; A61P3/00; A61P3/04
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
62 words
A pharmaceutical composition in dosage unit form with anorectic activity comprising from 1 to 500 mg of an active ingredient selected from the group consisting of trifluoromethylphenyl-1,2,3,6-tetrahydropyridines of formula ##STR7## wherein R is cyano, and Alk represents a straight or branched alkylene group having 1 to 4 carbon atoms, or a pharmaceutically-acceptable acid addition salt thereof, in admixture with a pharmaceutically-acceptable carrier.
Claim 2
Dependent Claim
62 words
A pharmaceutical composition in dosage unit form with anorectic activity comprising from 1 to 500 mg of an active ingredient selected from the group consisting of trifluoromethylphenyl-1,2,3,6-tetrahydropyridines of formula ##STR7## wherein R is cyano, and Alk represents a straight or branched alkylene group having 1 to 4 carbon atoms, or a pharmaceutically-acceptable acid addition salt thereof, in admixture with a pharmaceutically-acceptable carrier.
Claim 3
Dependent Claim
15 words
A pharmaceutical composition as claimed in claim 1 wherein the active ingredient is 4-(3-trifluoromethylphenyl)-1-(2-cyanoethyl)-1,2,3,6-tetrahydropyridine hydrochloride.
Claim 4
Dependent Claim
15 words
A pharmaceutical composition as claimed in claim 1 wherein the active ingredient is 4-(3-trifluoromethylphenyl)-1-(3-cyanopropyl)-1,2,3,6-tetrahydropyridine hydrochloride.
Claim 5
Dependent Claim
15 words
A pharmaceutical composition as claimed in claim 1 wherein the active ingredient is 4-(3-trifluoromethylphenyl)-1-(2-cyano-1-methyl)ethyl-1,2,3,6-tetrahydropyridine hydrochloride.
References Cited (Backward Citations)
US3072648A
Cited
US3125488A
Cited
GB881894A
Cited
GB948071A
Cited
GB984364A
Cited
US3284457A
Cited
US3626066A
Cited
US3627775A
Cited
DE2101997A1
Cited
US4012374A
Cited
US4024151A
Cited
US4213989A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1989-07-21 | 1990-01-20 | 1990-07-22 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1993-07-21 | 1994-01-20 | 1994-07-22 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1997-07-21 | 1998-01-20 | 1998-07-22 | $7700.00 | Window Closed / Lapsed |