US4602024A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Substituted trifluoromethylphenyltetrahydropyridines having a cyano substituent and an anorectic activity, a process for preparing same and pharmaceutical compositions
Assignee: Elf Sanofi SA
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Filing: 1984-07-16
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Granted: 1986-07-22
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Expires: 2004-07-16
Abstract
Abstract The invention relates to 4-(-3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridines of formula <IMAGE> in which R represents a cyano, acetyl or cycloalkyl group of from 3 to 7 carbon atoms and Alk represents a straight or branched alkylene of from 1 to 4 carbon atoms, as well as to the salts thereof, having an anorectic activity, to a process for preparing same and to pharmaceutical compositions containing said compounds, useful in the treatment of obesity.
Inventors
- 👤 Dino Nisato
- 👤 Emilio Crisafulli
- 👤 Alberto Bianchetti
- 👤 Paolo Carminati
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 17:53
CPC Classifications
C; C07; C07D; C07D211/00; C07D211/04; C07D211/68; C07D211/70; A; A61; A61P; A61P3/00; A61P3/04
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
62 words
A pharmaceutical composition in dosage unit form with anorectic activity comprising from 1 to 500 mg of an active ingredient selected from the group consisting of trifluoromethylphenyl-1,2,3,6-tetrahydropyridines of formula ##STR7## wherein R is cyano, and Alk represents a straight or branched alkylene group having 1 to 4 carbon atoms, or a pharmaceutically-acceptable acid addition salt thereof, in admixture with a pharmaceutically-acceptable carrier.
Claim 2
Dependent Claim
62 words
A pharmaceutical composition in dosage unit form with anorectic activity comprising from 1 to 500 mg of an active ingredient selected from the group consisting of trifluoromethylphenyl-1,2,3,6-tetrahydropyridines of formula ##STR7## wherein R is cyano, and Alk represents a straight or branched alkylene group having 1 to 4 carbon atoms, or a pharmaceutically-acceptable acid addition salt thereof, in admixture with a pharmaceutically-acceptable carrier.
Claim 3
Dependent Claim
15 words
A pharmaceutical composition as claimed in claim 1 wherein the active ingredient is 4-(3-trifluoromethylphenyl)-1-(2-cyanoethyl)-1,2,3,6-tetrahydropyridine hydrochloride.
Claim 4
Dependent Claim
15 words
A pharmaceutical composition as claimed in claim 1 wherein the active ingredient is 4-(3-trifluoromethylphenyl)-1-(3-cyanopropyl)-1,2,3,6-tetrahydropyridine hydrochloride.
Claim 5
Dependent Claim
15 words
A pharmaceutical composition as claimed in claim 1 wherein the active ingredient is 4-(3-trifluoromethylphenyl)-1-(2-cyano-1-methyl)ethyl-1,2,3,6-tetrahydropyridine hydrochloride.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1989-07-21 | 1990-01-20 | 1990-07-22 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1993-07-21 | 1994-01-20 | 1994-07-22 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1997-07-21 | 1998-01-20 | 1998-07-22 | $7700.00 | Window Closed / Lapsed |