US4601898A
Expired / Lapsed
US
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Aqueous solution containing TiF4 and chelating agent
Assignee: GlaxoSmithKline LLC
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Filing: 1985-03-27
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Granted: 1986-07-22
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Expires: 2005-03-27
Abstract
Abstract An anti-caries aqueous solution, which comprises an aqueous solution containing an anti-caries effective amount of TiF 4 and a chelating agent in an amount effective to stablilize the TiF 4 , said solution having a pH of at least about 3.5.
Inventors
- 👤 Roger E. Stier
- 👤 William H. Dunn
- 👤 James D. Vidra
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-05 14:26
CPC Classifications
A; A61; A61Q; A61Q11/00; A61K; A61K8/00; A61K8/18; A61K8/19; A61K8/20; A61K8/21; A61K8/30; A61K8/33; A61K8/36; A61K8/365; A61K2800/00; A61K2800/40; A61K2800/51
Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
75 words
An anti-caries aqueous solution, consisting essentially of an aqueous solution containing an anti-caries effective amount in the range of from about 0.04 to about 2.5% of TiF 4 and a chelating agent in an amount of from about 0.10 to about 15% and effective to stabilize the TiF 4 , said solution having a pH of from about 3.5 to about 5.5, the percentages being by weight based on the total weight of the solution.
Claim 2
Dependent Claim
75 words
An anti-caries aqueous solution, consisting essentially of an aqueous solution containing an anti-caries effective amount in the range of from about 0.04 to about 2.5% of TiF 4 and a chelating agent in an amount of from about 0.10 to about 15% and effective to stabilize the TiF 4 , said solution having a pH of from about 3.5 to about 5.5, the percentages being by weight based on the total weight of the solution.
Claim 3
Dependent Claim
26 words
The aqueous solution according to claim 1, wherein the weight ratio of said chelating agent to said TiF 4 is from about 1:1 to about 5:1.
Claim 4
Dependent Claim
34 words
The aqueous solution according to claim 1, wherein said chelating agent is selected from the group consisting of chelating agents having one or more chelating hydroxy, carboxy or sulfonic acid groups and metal chelates.
Claim 5
Dependent Claim
36 words
The aqueous solution according to claim 1, which comprises from about 0.10 to about 0.30% of TiF 4 and from about 0.10 to about 1.5% of said chelating agent, by weight based on the total composition.
Claim 6
Dependent Claim
35 words
The aqueous solution according to claim 1, which comprises from about 1.0 to about 2.5% TiF 4 and from about 1.0 to about 12.5% of said chelating agent, by weight based on the total composition.
Claim 7
Dependent Claim
57 words
The aqueous solution according to claim 1, wherein said chelating agent is selected from the group consisting of ethylenediaminetetraacetic acid, salicyclic acid, citric acid, 2,4 and 2,6-dihydroxybenzoic acids, dihydroxytartaric acid, nitrilotriacetic acid, tartaric acid, 4,5-dihydroxy-1,3-benzenedisulfonic acid, mandelic acid, malic acid, mellitic acids, oxalic acid, acetic acid and metal chelates or a mixture of two or more thereof.
Claim 8
Dependent Claim
17 words
The aqueous solution according to claim 1, wherein said chelating agent contains chelating hydroxy and carboxy groups.
Claim 9
Dependent Claim
22 words
The aqueous solution according to claim 7, wherein the chelating agent is tartaric acid, citric acid or an alkali metal salt thereof.
Claim 10
Dependent Claim
17 words
The aqueous solution according to claim 4, wherein said chelating agent contains chelating hydroxy and carboxy groups.
Claim 11
Dependent Claim
23 words
The aqueous solution according to claim 1, in the form of an anti-caries mouthrinse and further comprising alcohol, a humectant and a surfactant.
Claim 12
Dependent Claim
22 words
The aqueous solution according to claim 9, wherein the chelating agent is tartaric acid, citric acid or an alkali metal salt thereof.
Claim 13
Dependent Claim
17 words
The aqueous solution according to claim 5, wherein said chelating agent contains chelating hydroxy and carboxy groups.
Claim 14
Dependent Claim
22 words
The aqueous solution according to claim 4, wherein said chelating agent is tartaric acid, citric acid or an alkali metal salt thereof.
Claim 15
Dependent Claim
22 words
The aqueous solution according to claim 5, wherein said chelating agent is tartaric acid, citric acid or an alkali metal salt thereof.
References Cited (Backward Citations)
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