Patent US4596827A successfully refreshed from Google Patents.
US4596827A
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US
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Alkylsulfonamidophenylalkylamine compounds used for treating arrhythmia
Assignee: Eli Lilly and Co
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Filing: 1985-11-07
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Granted: 1986-06-24
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Expires: 2005-11-07
Abstract
Abstract The present invention relates to a new class of alkylsulfonamidophenylalkylamines which are potent antiarrhythmic agents having good oral bioavailability properties.
Inventors
- 👤 Bryan B. Molloy
- 👤 Mitchell I. Steinberg
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-31 19:48
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/16; A61K31/18; C; C07; C07C; C07C311/00; C07C311/01; C07C311/02
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
99 words
A method for treating arrhythmia in mammals which comprises administering to a mammal suffering from an arrhythmia and in need of treatment or to a mammal suspected of developing an arrhythmia a pharmaceutically-effective amount of a compound of the formula ##STR3## wherein: R is C 1 -C 6 alkyl; R 1 is hydrogen, methyl or ethyl; R 2 is hydrogen or C 1 -C 3 alkyl; R 3 is hydrogen or C 1 -C 8 alkyl; R 4 is C 1 -C 10 alkyl; n is 2, 3, 4 or 5; or the pharmaceutically acceptable acid addition salts thereof.
Claim 2
Independent Claim
99 words
A method for treating arrhythmia in mammals which comprises administering to a mammal suffering from an arrhythmia and in need of treatment or to a mammal suspected of developing an arrhythmia a pharmaceutically-effective amount of a compound of the formula ##STR3## wherein: R is C 1 -C 6 alkyl; R 1 is hydrogen, methyl or ethyl; R 2 is hydrogen or C 1 -C 3 alkyl; R 3 is hydrogen or C 1 -C 8 alkyl; R 4 is C 1 -C 10 alkyl; n is 2, 3, 4 or 5; or the pharmaceutically acceptable acid addition salts thereof.
Claim 3
Dependent Claim
17 words
The method of claim 1 wherein the compound is N-[4-[4-(ethylheptylamino)butyl]phenyl]methanesulfonamide, or its pharmaceutically acceptable acid addition salts.
Claim 4
Dependent Claim
11 words
The method of claim 2 wherein the compound is N-[4-[4-(ethylheptylamino)butyl]phenyl]methanesulfonamide ethanedioate.
Claim 5
Dependent Claim
11 words
The method of claim 2 wherein the compound is N-[4-[4-(ethylheptylamino)butyl]phenyl]methanesulfonamide monohydrobromide.
Claim 6
Dependent Claim
11 words
The method of claim 2 wherein the compound is N-[4-[4-(ethylheptylamino)butyl]phenyl]methanesulfonamide benzenesulfonate.
Claim 7
Dependent Claim
11 words
The method of claim 2 wherein the compound is N-[4-[4-(ethylheptylamino)butyl]phenyl]methanesulfonamide monohydrochloride.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1989-06-23 | 1989-12-23 | 1990-06-24 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1993-06-23 | 1993-12-23 | 1994-06-24 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1997-06-23 | 1997-12-23 | 1998-06-24 | $7700.00 | Window Closed / Lapsed |