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US4594346A
Expired / Lapsed
US
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3,6-disubstituted-1,8-naphthalimides and methods for their production and use
Assignee: Warner Lambert Co LLC
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Filing: 1985-01-22
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Granted: 1986-06-10
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Expires: 2005-01-22
Abstract
Abstract Chemical compounds are provided that are novel 3,6-disubstituted-1,8-naphthalimides (I), as well as methods for their production, pharmaceutical compositions comprising the compounds, and methods of treatment using the compounds in dosage form. Compounds of the invention have pharmacological properties and are useful antimicrobial agents. ##STR1##
Inventors
- 👤 Robert K. Zee-Cheng
- 👤 Chia C. Cheng
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 09:33
CPC Classifications
C; C07; C07D; C07D221/00; C07D221/02; C07D221/04; C07D221/06; C07D221/14
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
79 words
A method for treating transplantable leukemia in a lower mammal which comprises administering an antileukemically effective amount of a compound having in free base form the structural formula I ##STR8## or a pharmaceutically acceptable salt thereof, where n is 2 or 3, R 1 and R 2 are H, lower alkyl, lower hydroxyalkyl, pyrrolidinyl, morpholino, or piperidinyl, and Y is NO 2 or HN 2 , in combination with a pharmaceutically acceptable carrier, to a mammal in need thereof.
Claim 2
Independent Claim
79 words
A method for treating transplantable leukemia in a lower mammal which comprises administering an antileukemically effective amount of a compound having in free base form the structural formula I ##STR8## or a pharmaceutically acceptable salt thereof, where n is 2 or 3, R 1 and R 2 are H, lower alkyl, lower hydroxyalkyl, pyrrolidinyl, morpholino, or piperidinyl, and Y is NO 2 or HN 2 , in combination with a pharmaceutically acceptable carrier, to a mammal in need thereof.
References Cited (Backward Citations)
US3940398A
Cited
US4146720A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1989-06-09 | 1989-12-09 | 1990-06-10 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1993-06-09 | 1993-12-09 | 1994-06-10 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1997-06-09 | 1997-12-09 | 1998-06-10 | $7700.00 | Window Closed / Lapsed |