Dentifrices

Claim 2

An antimicrobial antiplaque dentifrice comprising, in addition to conventional dentifrice ingredients in usual amounts, about 6%, calculated on the total weight of the dentifrice, of povidone-iodine complex or Biopal as iodophor as a first part and about 2%, on the same basis, of a separate source of active or oxygen such as carbamide peroxide as a second part, whereby during use of the dentifrice the two parts are admixed and provide an effective antimicrobial antiplaque non-toxic amount of iodine derived from the iodophor of the first part, the antimicrobial activity of which is enhanced or potentiated by interaction with the source of oxygen and/or the active or nascent oxygen released therefrom.

Claim 3

A dentifrice according to claim 1, wherein the oxygen source is H 2 O 2 , carbamide peroxide, benzoyl peroxide, sodium chlorite or other source of oxygen.

Claim 4

A dentifrice according to claim 1, wherein the oxygen source is carbamide peroxide and the peroxide formulation and the iodophor formulation are present in a 1:1 v/v proportion.

Claim 5

A dentifrice according to claim 1, wherein the iodophor is the povidone-iodine complex.

Claim 6

A dentifrice according to claim 1 formulated for use in paste, gel or powder form.

Claim 7

A non-toxic antiplaque, anticavity dentifrice in toothpaste or gel form containing as its active ingredients an antimicrobially active antiplaque amount of an iodophor formulation and carbamide peroxide formulation in approximately equal amounts, optionally including 0.1-1.0% by weight of the toothpaste or gel of an anticaries fluoride compound.

Claim 8

A non-toxic antiplaque, anticavity dentifrice in toothpaste or gel form containing as its active ingredients an antimicrobially active antiplaque amount of an iodophor formulation and carbamide peroxide formulation in approximately equal amounts, optionally including 0.1-1.0% by weight of the toothpaste or gel of an anticaries fluoride compound.

Claim 9

An antimicrobial, antiplaque dentifrice which during use is constituted of a mixture of two components, each of which components contains the same or similar conventional dentifrice components in like amounts but wherein one part contains an iodophor and the other part contains a compound which is a source of oxygen, the two components being kept separated from one another until they are to be used whereupon the components are admixed and dispensed as a complete dentifrice, the antimicrobial and antiplaque activity is enhanced or potentiated by interaction with the source of oxygen and/or the active or nascent oxygen released therefrom.

Claim 10

An antimicrobial, antiplaque dentifrice which during use is constituted of a mixture of two components, each of which components contains the same or similar conventional dentifrice components in like amounts but wherein one part contains an iodophor and the other part contains a compound which is a source of oxygen, the two components being kept separated from one another until they are to be used whereupon the components are admixed and dispensed as a complete dentifrice, the antimicrobial and antiplaque activity is enhanced or potentiated by interaction with the source of oxygen and/or the active or nascent oxygen released therefrom.

Claim 11

A dentifrice according to claim 7 in which each of the said components is filled into a separate compartment of a sealed but openable container for the dentifrice and upon exerting pressure on the opened container the two dentifrice components are simultaneously admixed and extruded.

Claim 12

A dentifrice according to claim 8 wherein the dentifrice container has disposed therewithin two separate but connectable dentifrice spaces or compartments, each of which contains one component of the dentifrice and wherein the components are out of contact with one another prior to extrusion from the container ready for use.

Claim 13

A dentifrice according to claim 8 wherein the two dentifrice components are out of contact with one another prior to extrusion from the container by aerosolization.

Claim 14

An antimicrobial antiplaque dentifrice according to claim 1 wherein the PVP-I and peroxide components have the following percentage compositions: ______________________________________ PVP-I Peroxide Component Component ______________________________________ Water 26.64 31.39 PVP-I (calculated as powder, 6.66 -- 10% I.sub.2) Carbamide Peroxide -- 1.86 Sodium carboxymethylcellulose 1.25 1.25 Sorbitol 23.75 23.75 Dicalcium phosphate dihydrate 40.2 40.2 Sodium lauryl sulfate 1.5 1.5 Flavor, sweetener q.s. q.s. ______________________________________

Claim 15

An antimicrobial antiplaque dentifrice according to claim 1 wherein the PVP-I and peroxide components have the following percentage compositions: ______________________________________ PVP-I Peroxide Component Component ______________________________________ PVP-I (calculated as powder, 10.0 -- Carbamide Peroxide -- 8.3 Calcium carbonate 34.0 40.0 Sorbitol 23.8 18.7 Sodium lauryl sulfate 1.5 1.5 CMC (12 HP) 1.3 1.3 Water 29.4 30.2 Flavor, sweetener q.s. q.s. ______________________________________

Claim 16

An antimicrobial antiplaque dentifrice according to claim 1 wherein the PVP-I and peroxide components have the following percentage compositions: ______________________________________ PVP-I Peroxide Component Component ______________________________________ PVP-I (calculated as powder, 10.00 -- 10% I.sub.2) Carbamide Peroxide -- 8.3 Silica (e.g., Syloid 244) 15.0 20.0 Sorbitol 20.0 20.0 Sodium lauryl sulfate 1.5 1.5 CMC (12 HP) 3.0 3.0 Water 50.5 47.2 Flavor, sweetener q.s. q.s. ______________________________________

Claim 17

An antimicrobial antiplaque dentifrice according to claim 1 wherein the PVP-I and peroxide components have the following percentage compositions: ______________________________________ PVP-I Peroxide Component Component ______________________________________ PVP-I (calculated as powder, 10.0 -- 10% I.sub.2) Dicalcium phosphate dihydrate 69.0 70.7 Calcium carbonate 20.0 20.0 Sodium lauryl sulfate 1.0 1.0 Flavor, sweetener q.s. q.s. Carbamide peroxide -- 8.3 ______________________________________

Claim 18

An antimicrobial antiplaque dentifrice according to claim 1 wherein the PVP-I and peroxide components have the following percentage compositions: ______________________________________ PVP-I Peroxide Component Component ______________________________________ PVP-I (calculated as powder, 10.0 -- 10% I.sub.2) Aluminum magnesium silicate 1.5 1.5 Benzoyl peroxide -- 16.1 Sodium carboxymethylcellulose 0.5 0.5 (med. visc.) Water 30.3 24.2 Sodium saccharine 0.2 0.2 Sorbitol (70% solution) 15.0 15.0 Glycerin 10.0 10.0 Dicalcium phosphate dihydrate 26.0 26.0 Tricalcium phosphate 5.0 5.0 Sodium lauryl sulfate 1.5 1.5 Flavor q.s. q.s. ______________________________________

Claim 19

An antimicrobial antiplaque dentifrice according to claim 1 wherein the PVP-I and peroxide components have the following percentage compositions: ______________________________________ PVP-I Peroxide Component Component ______________________________________ PVP-I (calculated as powder, 10.00 -- 10% I.sub.2) Carbamide Peroxide -- 8.3 Sorbitol (70% solution) 20.00 15.00 Calcium pyrophosphate 40.00 26.00 Sodium monofluorophosphate 0.76 -- Glycerin 5.00 1.50 Sodium lauryl sulfate 1.50 1.50 Magnesium aluminum silicate 0.40 1.50 Sodium carboxymethylcellulose 1.15 0.5 Stannous gluconate (31% solution) 10.00 37.2 Water 11.19 37.2 Flavor q.s. q.s. ______________________________________