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US4587018A
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Fibrin gel
Assignee: New York Blood Center
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Filing: 1984-11-16
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Granted: 1986-05-06
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Expires: 2004-11-16
Abstract
Abstract There is disclosed a filter comprising fibrin in gel form, the gel having substantially uniform pore sizes, and the filter comprising means for retaining the shape of at least one surface of the gel against deformation when contacted by a flowing medium.
Inventors
- 👤 Birger Blomback
- 👤 Masahisa Okada
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 03:22
CPC Classifications
C; C12; C12N; C12N11/00; C12N11/02; C12N11/04; B; B01; B01D; B01D39/00; B01D71/00; B01D71/06; B01D71/74; C07; C07K; C07K14/00; C07K14/435; C07K14/745; C07K14/755; C12N1/00; C12N1/02; C12N7/00; A; A61; A61K; A61K38/00; C12N2760/00; C12N2760/00011; C12N2760/18011; C12N2760/18811; C12N2760/18851; Y; Y02; Y02A; Y02A50/00; Y02A50/30; Y10; Y10S; Y10S435/00; Y10S435/811; Y10S435/82; Y10T; Y10T436/00; Y10T436/25; Y10T436/25375; Y10T436/255
Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
58 words
A fibrin gel containing therein at least one catalytically active substance selected from the group consisting of a catalytically active enzyme or a catalytically active metal, said fibrin gel having substantially uniform pore sizes and containing means for retaining the shape of at least the upper surface of the gel against deformation when contacted by a flowing medium.
Claim 2
Dependent Claim
58 words
A fibrin gel containing therein at least one catalytically active substance selected from the group consisting of a catalytically active enzyme or a catalytically active metal, said fibrin gel having substantially uniform pore sizes and containing means for retaining the shape of at least the upper surface of the gel against deformation when contacted by a flowing medium.
Claim 3
Dependent Claim
31 words
A fibrin gel according to claim 1 wherein said means for retaining the shape of at least the upper surface of said gel comprises a foraminous sheet member or a foam.
Claim 4
Dependent Claim
19 words
A fibrin gel according to claim 1 wherein said fibrin gel is itself disposed in a porous plastic material.
Claim 5
Dependent Claim
17 words
A fibrin gel according to claim 1 wherein said fibrin gel is disposed in a cellulose matrix.
Claim 6
Dependent Claim
21 words
A fibrin gel according to claim 3 wherein said porous plastic material is a porous plastic that is wettable by water.
Claim 7
Dependent Claim
14 words
A fibrin gel according to claim 5 wherein said porous plastic material is polyurethane.
Claim 8
Dependent Claim
14 words
A fibrin gel according to claim 5 wherein said porous plastic material is polyester.
Claim 9
Dependent Claim
24 words
A fibrin gel according to claim 1 wherein said fibrin gel has substantially uniform pores of a theoretical diameter of 0.003 to 1 μm.
Claim 10
Dependent Claim
21 words
A fibrin gel according to claim 8 wherein said gel has pores of a theoretical diameter of 0.009 to 0.3 μm.
Claim 11
Dependent Claim
15 words
A fibrin gel according to claim 1 wherein said substance is a catalytically active metal.
Claim 12
Dependent Claim
15 words
A fibrin gel according ro claim 1 wherein said substance is a catalytically active enzyme.
Claim 13
Dependent Claim
47 words
A fibrin gel according to claim 11 wherein said enzyme is an enzyme selected from the group consisting of an oxido-reductase, a transferase, a hydrolase, a lyase, an isomerase, and a ligasis except a hydrolase which has the capacity of degrading a protein strand in a gel.
Claim 14
Dependent Claim
40 words
A fibrin gel having substantially uniform pore sizes and containing means for retaining the shape of at least the upper surface of the gel against deformation when contacted by a flowing medium, said gel having disposed within its pores leukocytes.
Claim 15
Dependent Claim
40 words
A fibrin gel having substantially uniform pore sizes and containing means for retaining the shape of at least the upper surface of the gel against deformation when contacted by a flowing medium, said gel having disposed within its pores leukocytes.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1989-05-05 | 1989-11-04 | 1990-05-06 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1993-05-05 | 1993-11-04 | 1994-05-06 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1997-05-05 | 1997-11-04 | 1998-05-06 | $7700.00 | Window Closed / Lapsed |