US4585651A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Active/passive immunization of the internal female reproductive organs
Assignee: Alkermes Controlled Therapeutics Inc II
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Filing: 1980-12-18
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Granted: 1986-04-29
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Expires: 2000-12-18
Abstract
Abstract Antibody or antigen containing microparticles for the active or passive immunization of the internal female reproductive organs, comprising: microparticles of an antigen or antibody incorporated in a matrix material which is biocompatible and biologically degradable, said microparticles capable of being transported after deposition in the vagina by the natural transport mechanism of the internal female reproductive organs across the cervix into the uterus.
Inventors
- 👤 Lee R. Beck
- 👤 Charles F. Flowers, Jr.
- 👤 Donald R. Cowsar
- 👤 Albert C. Tanquary
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 16:08
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/14; A61K9/16; A61K9/1605; A61K9/1629; A61K9/1641; A61K9/1647; A61K31/00; A61K31/56; A61K39/00; A61K9/0012; A61K9/0034; A61K9/0036; A61K9/1617; C; C07; C07K; C07K16/00; C12; C12N; C12N11/00; C12N11/02; C12N11/04; A61K38/00
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
63 words
A method of actively eliciting an immunization response of the internal female reproductive organs, comprising: depositing microparticles containing an antigen in the vagina; and allowing the natural transport mechanism of said organs to convey said microparticles across the cervix into the uterus and fallopian tubes, whereby said antigen is released by said microparticles so as to elicit an antibody response within the uterus.
Claim 2
Independent Claim
63 words
A method of actively eliciting an immunization response of the internal female reproductive organs, comprising: depositing microparticles containing an antigen in the vagina; and allowing the natural transport mechanism of said organs to convey said microparticles across the cervix into the uterus and fallopian tubes, whereby said antigen is released by said microparticles so as to elicit an antibody response within the uterus.
Claim 3
Dependent Claim
18 words
The method of claim 1, wherein said microparticles are of a size ranging from 20 to 70 μm.
Claim 4
Dependent Claim
17 words
The method of claim 1, wherein said matrix material is polylactic acid, polyglycolic acid or mixtures thereof.
Claim 5
Dependent Claim
14 words
The method of claim 1, wherein said antigen is of bacterial or viral origin.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1989-04-28 | 1989-10-28 | 1990-04-29 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1993-04-28 | 1993-10-28 | 1994-04-29 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1997-04-28 | 1997-10-28 | 1998-04-29 | $7700.00 | Window Closed / Lapsed |