Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
138 words
A method of recovering biospecifically, sorbable components dispersed in an aqueous solution comprising: (a) contacting said solution as a first solution with an electrolytically conducting barrier having biospecific sorbing properties for at least one of said components whereby a substantial fraction of said components in said solution having biospecific binding affinity for said barrier is sorbed by said barrier; (b) removing said first solution from contact with the said barrier; (c) contacting said barrier with a second aqueous solution; (d) passing a direct electric current through said barrier and said second solution in a direction approximately parallel to the smallest dimension of said barrier thereby facilitating the desorption of at least one of said components having biospecific binding affinity for the said barrier into said second solution; and (e) removing said second solution from contact with said barrier.
Claim 2
Independent Claim
138 words
A method of recovering biospecifically, sorbable components dispersed in an aqueous solution comprising: (a) contacting said solution as a first solution with an electrolytically conducting barrier having biospecific sorbing properties for at least one of said components whereby a substantial fraction of said components in said solution having biospecific binding affinity for said barrier is sorbed by said barrier; (b) removing said first solution from contact with the said barrier; (c) contacting said barrier with a second aqueous solution; (d) passing a direct electric current through said barrier and said second solution in a direction approximately parallel to the smallest dimension of said barrier thereby facilitating the desorption of at least one of said components having biospecific binding affinity for the said barrier into said second solution; and (e) removing said second solution from contact with said barrier.
Claim 3
Dependent Claim
150 words
Apparatus for recovering biospecifically, sorbable components dispersed in an aqueous solution comprising: (a) an electrolytically conducting barrier having biospecific sorbing properties for at least one of said components; (b) means for contacting said solution with said barrier whereby components in said solution having biospecific binding affinity for said barrier are at least in part sorbed by said barrier; (c) means for removing said solution from contact with said barrier; (d) means for contacting said barrier with a second aqueous solution as a receiving solution; (e) means for passing a direct electric current through said barrier and said second solution in a direction approximately parallel to the smallest dimension of said barrier thereby to facilitate the desorption from said barrier of at least one of said components having biospecific binding affinity for said barrier into said second solution and (f) means for removing said second solution from contact with said barrier.
Claim 4
Dependent Claim
150 words
Apparatus for recovering biospecifically, sorbable components dispersed in an aqueous solution comprising: (a) an electrolytically conducting barrier having biospecific sorbing properties for at least one of said components; (b) means for contacting said solution with said barrier whereby components in said solution having biospecific binding affinity for said barrier are at least in part sorbed by said barrier; (c) means for removing said solution from contact with said barrier; (d) means for contacting said barrier with a second aqueous solution as a receiving solution; (e) means for passing a direct electric current through said barrier and said second solution in a direction approximately parallel to the smallest dimension of said barrier thereby to facilitate the desorption from said barrier of at least one of said components having biospecific binding affinity for said barrier into said second solution and (f) means for removing said second solution from contact with said barrier.
Claim 5
Dependent Claim
15 words
Apparatus according to claim 2 in which said barrier has the form of a cylinder.
Claim 6
Dependent Claim
15 words
Apparatus according to claim 2 in which said barrier has the form of a spiral.
Claim 7
Dependent Claim
59 words
Apparatus according to claim 2 in which said barrier contain ligands selected from the group consisting of enzyme inhibitors, enzyme substrate analogues, coenzymes, apoenzyme polymeric substrates, enzymes, nucleic acid complementary strands, haptens, antibodies, monosaccharides, polysaccharides, lectins, small target compounds for binding proteins, binding proteins, aminobenzamidine, 5' adenosine monophosphate, S. aureus Protein A, hormones, hormone receptors, and immobilized textile dyes.
Claim 8
Dependent Claim
35 words
Apparatus according to claim 2 in which said barrier is selected from the group consisting of ion-selective membranes, sheets of hydrous gels and porous sheets having average pore sizes of less than about 10 micrometers.
Claim 9
Dependent Claim
14 words
Apparatus according to claim 2 in which said barrier is a macroreticular ion-selective membrane.
Claim 10
Dependent Claim
20 words
Apparatus according to claim 2 in which said barrier is an ion-selective membrane having ligands attached to a macroreticular surface.
Claim 11
Dependent Claim
15 words
Apparatus according to claim 2 in which said barrier is a bipolar ion selective membrane.