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US4582832A Expired / Lapsed US ⏱️ 0.0 years remaining

Trimazosin as an anti-atherosclerosis agent

Assignee: Pfizer Inc
•
Filing: 1985-08-28
•
Granted: 1986-04-15
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Expires: 2005-08-28
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Abstract

Abstract The use of trimazosin or a pharmaceutically acceptable acid addition salt thereof as an agent for retarding the development of atherosclerosis in a mammal, especially for retarding and reducing the development of fibrous plaques associated with atherosclerosis.

Inventors

  • 👤 Archie C. Swindell

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-28 16:26
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/495; A61K31/505

Claims Analysis

Total Claims: 5
Claim 1
Independent Claim 46 words
A method of suppressing fibrosis of atherosclerotic lesions in a non-hypertensive mammal free of ischemic heart disease and of congestive heart failure but having atherosclerosis which comprises administering to said mammal a fibrosis lesion suppressing amount of trimazosin or a pharmaceutically acceptable acid addition salt thereof.
Claim 2
Independent Claim 46 words
A method of suppressing fibrosis of atherosclerotic lesions in a non-hypertensive mammal free of ischemic heart disease and of congestive heart failure but having atherosclerosis which comprises administering to said mammal a fibrosis lesion suppressing amount of trimazosin or a pharmaceutically acceptable acid addition salt thereof.
Claim 3
Dependent Claim 9 words
The method of claim 1 wherein trimazosin is administered.
Claim 4
Dependent Claim 11 words
The method of claim 2 wherein the trimazosin is administered orally.
Claim 5
Dependent Claim 20 words
The method of claim 3 wherein the trimazosin is administered orally at from about 0.16 mg/kg/day to about 9.6 mg/kg/day.

References Cited (Backward Citations)

US3669968A Cited
US4150119A Cited
US4130647A Cited
US4245097A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1989-04-14 1989-10-14 1990-04-15 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1993-04-14 1993-10-14 1994-04-15 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1997-04-14 1997-10-14 1998-04-15 $7700.00 Window Closed / Lapsed

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