US4574085A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method for using dialysis solution containing glycerol
Assignee: Baxter International Inc
•
Filing: 1981-05-15
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Granted: 1986-03-04
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Expires: 2001-05-15
Abstract
Abstract A dialysis solution, typically a peritoneal dialysis solution, comprises a water solution of physiological pH, having physiological salts and glycerine present in concentrations sufficient to safely effect the removal of solutes and water from a patient by peritoneal dialysis.
Inventors
- 👤 Ralph E. Dolkart
- 👤 Nicholas J. Kartinos
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 12:50
CPC Classifications
A; A61; A61M; A61M1/00; A61M1/14; A61M1/28; A61M1/287; A61K; A61K31/00; A61K31/045; A61K31/047; A61K31/185; A61K31/19; A61K31/195; A61K33/00; A61K33/14; A61P; A61P7/00
Claims Analysis
Total Claims: 17
Claim 1
Independent Claim
102 words
A method of performing peritoneal dialysis by inserting into the peritoneal cavity a substantially sugar-free dialysis solution which comprises a water solution of pH 5.6 to 7.4, having physiological salts and glycerin present in concentrations sufficient to safely effect the removal of solutes and water from the patient by diffusion through the peritoneal membrane, said glycerin being present in a concentration of 0.5 to 40 grams per liter; allowing said dialysis solution to dwell in the peritoneal cavity for a period of time sufficient to permit said diffusion of solutes in water; and thereafter removing said dialysis solution from the peritoneal cavity.
Claim 2
Independent Claim
102 words
A method of performing peritoneal dialysis by inserting into the peritoneal cavity a substantially sugar-free dialysis solution which comprises a water solution of pH 5.6 to 7.4, having physiological salts and glycerin present in concentrations sufficient to safely effect the removal of solutes and water from the patient by diffusion through the peritoneal membrane, said glycerin being present in a concentration of 0.5 to 40 grams per liter; allowing said dialysis solution to dwell in the peritoneal cavity for a period of time sufficient to permit said diffusion of solutes in water; and thereafter removing said dialysis solution from the peritoneal cavity.
Claim 3
Dependent Claim
16 words
The method of claim 1 in which said dialysis solution contains an amino acid source material.
Claim 4
Dependent Claim
20 words
The method of claim 1 in which said dialysis solution contains from 5 to 30 grams per liter of glycerol.
Claim 5
Dependent Claim
24 words
The method of claim 2 in which said dialysis solution contains from 5 to 30 grams per liter of said amino acid source material.
Claim 6
Dependent Claim
40 words
The method of claim 1 in which said dialysis solution contains from 130 to 140 MEq/liter of sodium, from 100 to 140 MEq/liter of chloride, from 0 to 6 MEq/liter of calcium, and from 0 to 4 MEq/liter of magnesium.
Claim 7
Dependent Claim
36 words
The method of claim 5 in which said solution also contains from 30 to 40 MEq/liter of at least one type of bicarbonate precursor ion selected from the group consisting of lactate, acetate, malate, and succinate.
Claim 8
Dependent Claim
18 words
The method of claim 1 in which said dialysis solution has an osmolarity of 272 to 700 milliosmols.
Claim 9
Dependent Claim
32 words
The method of claim 1 in which said dialysis solution contains an amount of a sulfhydryl-type antioxidant sufficent to improve the stability of the amino acids of said amino acid source material.
Claim 10
Independent Claim
91 words
A method of performing peritoneal dialysis by inserting into the peritoneal cavity a substantially sugar-free dialysis solution which comprises a water solution of physiological pH, having physiological salts present in concentrations sufficient to safely effect the removal of solutes from the patient through the peritoneal membrane, said solution containing from 0.5 to 40 grams per liter of glycerol to enhance the removal of water from the patient by diffusion through the peritoneal membrane, said dialysis solution having an osmolarity of 272 to 700 milliosmols and a pH of 5 to 7.4.
Claim 11
Independent Claim
91 words
A method of performing peritoneal dialysis by inserting into the peritoneal cavity a substantially sugar-free dialysis solution which comprises a water solution of physiological pH, having physiological salts present in concentrations sufficient to safely effect the removal of solutes from the patient through the peritoneal membrane, said solution containing from 0.5 to 40 grams per liter of glycerol to enhance the removal of water from the patient by diffusion through the peritoneal membrane, said dialysis solution having an osmolarity of 272 to 700 milliosmols and a pH of 5 to 7.4.
Claim 12
Dependent Claim
20 words
The method of claim 9 in which said dialysis solution contains from 5 to 30 grams per liter of glycerol.
Claim 13
Independent Claim
105 words
The method of performing peritoneal dialysis by inserting into the peritoneal cavity a substantially sugar-free dialysis solution which comprises a water solution of physiological pH, having physiological salts present in concentrations sufficient to safely effect the removal of solutes from the patient by diffusion through the peritoneal membrane, and having from 0.5 to 40 grams per liter of glycerol to enhance the removal of water from the patient by diffusion through the peritoneal membrane, said solution also containing from 5 to 30 grams per liter of an amino acid source material, an osmolarity of 272 to 700 milliosmols, and a pH of 5 to 7.4.
Claim 14
Independent Claim
105 words
The method of performing peritoneal dialysis by inserting into the peritoneal cavity a substantially sugar-free dialysis solution which comprises a water solution of physiological pH, having physiological salts present in concentrations sufficient to safely effect the removal of solutes from the patient by diffusion through the peritoneal membrane, and having from 0.5 to 40 grams per liter of glycerol to enhance the removal of water from the patient by diffusion through the peritoneal membrane, said solution also containing from 5 to 30 grams per liter of an amino acid source material, an osmolarity of 272 to 700 milliosmols, and a pH of 5 to 7.4.
Claim 15
Dependent Claim
20 words
The method of claim 11 in which said dialysis solution contains from 5 to 30 grams per liter of glycerol.
Claim 16
Dependent Claim
31 words
The method of claim 12 in which said dialysis solution contains an amount of a sulfhydryl antioxidant sufficient to improve the stability of amino acids of said amino acid source material.
Claim 17
Dependent Claim
64 words
The method of claim 13 in which said dialysis solution contains from 130 to 140 MEq/liter of sodium, from 100 to 140 MEq/liter of chloride, from 0 to 6 MEq/liter of calcium, from 0 to 4 MEq/liter of magnesium, from 30 to 40 MEq/liter of at least one type of bicarbonate precursor ion selected from the group consisting of lactate, acetate, malate, and succinate.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1989-03-03 | 1989-09-02 | 1990-03-04 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1993-03-03 | 1993-09-02 | 1994-03-04 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1997-03-03 | 1997-09-02 | 1998-03-04 | $7700.00 | Window Closed / Lapsed |