US4572920A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Fluoride interpolymeric resin
Assignee: Research Corp Technologies Inc
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Filing: 1985-03-20
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Granted: 1986-02-25
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Expires: 2005-03-20
Abstract
Abstract An interpolymeric resin and composition therefrom is provided for treating teeth to prevent dental caries by forming a protective barrier and providing a source of fluoride ions for release adjacent to the surface of the tooth. The resin includes an anion-exchange-site bearing monomer carrying fluoride ions, an acrylic comonomer, a crosslinking monomer, and, optionally, a wetting/etching monomer. The resin may have a high degree of crosslinking which then may include filler material to form a composite composition.
Inventors
- 👤 Henry R. Rawls
- 👤 Barbara F. Zimmerman
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-29 14:44
CPC Classifications
A; A61; A61Q; A61Q11/00; A61K; A61K6/00; A61K6/80; A61K6/884; A61K6/887; A61K8/00; A61K8/18; A61K8/19; A61K8/20; A61K8/21; A61K8/72; A61K8/81; A61K8/8141; A61K8/8152; A61K2800/00; A61K2800/40; A61K2800/54
Claims Analysis
Total Claims: 32
Claim 1
Independent Claim
60 words
An acrylic, controlled-fluoride-releasing interpolymer comprising the reaction product of: a. an anion-exchange-site bearing monomer carrying a fluoride ion in an amount sufficient to provide a caries-inhibiting amount of fluoride; b. a copolymerizable acrylic monomer selected from the group consisting of bis-MA; bis-GMA; bis-EMA; bis-PMA; UEDMA; TUDMA, c-HaDMA; c-HeDMA; c. a monomer which forms a cross-link in the resulting interpolymeric resin.
Claim 2
Dependent Claim
60 words
An acrylic, controlled-fluoride-releasing interpolymer comprising the reaction product of: a. an anion-exchange-site bearing monomer carrying a fluoride ion in an amount sufficient to provide a caries-inhibiting amount of fluoride; b. a copolymerizable acrylic monomer selected from the group consisting of bis-MA; bis-GMA; bis-EMA; bis-PMA; UEDMA; TUDMA, c-HaDMA; c-HeDMA; c. a monomer which forms a cross-link in the resulting interpolymeric resin.
Claim 3
Dependent Claim
11 words
The interpolymer of claim 1 wherein said acrylic monomer comprises bis-GMA.
Claim 4
Dependent Claim
11 words
The interpolymer of claim 1 wherein said acrylic monomer comprises bis-MA.
Claim 5
Dependent Claim
11 words
The interpolymer of claim 1 wherein said acrylic monomer comprises bis-EMA.
Claim 6
Dependent Claim
10 words
The interpolymer of claim 1 wherein said acrylic comprises bis-PMA.
Claim 7
Dependent Claim
11 words
The interpolymer of claim 1 wherein said acrylic monomer comprises UEDMA.
Claim 8
Dependent Claim
11 words
The interpolymer of claim 1 wherein said acrylic monomer comprises TUDMA.
Claim 9
Dependent Claim
11 words
The interpolymer of claim 1 wherein said acrylic monomer comprises c-HeDMA.
Claim 10
Dependent Claim
11 words
The interpolymer of claim 1 wherein said acrylic monomer comprises c-HaDMA.
Claim 11
Dependent Claim
11 words
The interpolymer of claim 1 which further comprises a wetting/etching monomer.
Claim 12
Dependent Claim
12 words
The interpolymer of claim 10 wherein said wetting/etching monomer is methacrylic acid.
Claim 13
Dependent Claim
30 words
The interpolymer of claim 1 wherein said acrylic monomer is included in an amount of from about 10% to about 99% based on the volume of unfilled prepolymerization reaction mixture.
Claim 14
Dependent Claim
15 words
The interpolymer of claim 12 wherein said amount is from about 50% to about 75%.
Claim 15
Dependent Claim
31 words
The interpolymer of claim 1 wherein said fluoride carrying monomer is included in an amount of from about 1% to about 40% based on the volume of unfilled prepolymerized reaction mixture.
Claim 16
Dependent Claim
15 words
The interpolymer of claim 14 wherein said amount is from about 10% to about 30%.
Claim 17
Dependent Claim
31 words
The interpolymer of claim 1 wherein said monomeric crosslinker is selected from the group consisting of ethylene glycol dimethacrylate, trimethylolpropane trimethyacrylate, triethylene glycol dimethacrylate, diethylene glycol dimethacrylate, and polyethylene glycol dimethacrylate.
Claim 18
Dependent Claim
32 words
The interpolymer of claim 16 wherein said crosslinker is included in said interpolymer in an amount of from about 0.5% to about 80% based on the volume of unfilled prepolymerization reaction mixture.
Claim 19
Dependent Claim
15 words
The interpolymer of claim 17 wherein said amount is from about 10% to about 25%.
Claim 20
Dependent Claim
46 words
The interpolymer of claim 1 wherein said fluoride carrying monomer is selected from the group consisting of the quaternary fluoride salt of an aminoalkylacrylate, the hydrogen fluoride salt of an aminoalkylacrylate, the quaternary fluoride salt of an aminoalkylmethacrylate and the hydrogen fluoride salt of an aminoalkylmethacrylate.
Claim 21
Dependent Claim
64 words
The interpolymer of claim 19 wherein said aminoalkylacrylates and said aminoalkylmethacrylates have the general formula: ##STR6## in which R 1 is H or CH 3 , X is an integer of 1 to 12, R 2 is H or an alkyl grop of C 1 to C 4 and R 3 is H or an alkyl group of C 1 to C 12 .
Claim 22
Dependent Claim
10 words
The interpolymer of claim 20 wherein said monomer is DMAEMA.HF.
Claim 23
Dependent Claim
10 words
The interpolymer of claim 20 wherein said monomer is DEAEMA.HF.
Claim 24
Dependent Claim
35 words
A composition of matter comprising the interpolymer of claim 20 which is highly crosslinked and a filler in an amount of from about 5 to about 90% based on the total weight of said composition.
Claim 25
Dependent Claim
14 words
The composition of matter of claim 23 wherein said filler is an inorganic silicate.
Claim 26
Dependent Claim
23 words
The composition of matter of claim 23 wherein said filler is one of apatite phosphates, silica, glass, quartz, alumina or silanized versions thereof.
Claim 27
Dependent Claim
16 words
The interpolymer of claim 1 wherein said acrylic fluoride containing monomer is t-butylaminoethyl methacrylate hydrogen fluoride.
Claim 28
Dependent Claim
16 words
The interpolymer of claim 1 wherein said acrylic fluoride containing monomer is N,N, N-trimethylamino ethylmethacrylate fluoride.
Claim 29
Dependent Claim
16 words
A method of preventing dental caries comprising impregnating a tooth with the interpolymer of claim 1.
Claim 30
Dependent Claim
19 words
A method of preventing dental caries comprising impregnating a tooth with the interpolymer of claim 1 and a polyalkylacrylate.
Claim 31
Dependent Claim
16 words
A method of preventing dental caries comprising depositing the composition of claim 1 on a tooth.
Claim 32
Dependent Claim
24 words
A method of preventing dental caries comprising use of a fixed or removable oral device fabricated by use of the interpolymer of claim 1.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1989-02-24 | 1989-08-26 | 1990-02-25 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1993-02-24 | 1993-08-26 | 1994-02-25 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1997-02-24 | 1997-08-26 | 1998-02-25 | $7700.00 | Window Closed / Lapsed |