US4146608A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Synergistic anti-plaque mixture with tetradecylamine and copper, iron, nickel, or cobalt
Assignee: Lever Brothers Co
•
Filing: 1977-11-07
•
Granted: 1979-03-27
•
Expires: 1997-11-07
Abstract
Abstract A method and a composition for retarding plaque are disclosed. The composition includes a synergistic mixture of tetradecylamine in combination with copper, iron, nickel and/or cobalt, each of which may be used singly or in admixture in combination with the amine. The method generally includes applying a mixture of the tetradecylamine in combination with one or more of the above metals to the site of the plaque.
Inventors
- 👤 Thomas W. Ritchey
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-27 10:39
CPC Classifications
A; A61; A61Q; A61Q11/00; A61K; A61K8/00; A61K8/18; A61K8/19; A61K8/30; A61K8/40; A61K8/41; A61K2800/00; A61K2800/40; A61K2800/59
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
69 words
A substantially non-toxic composition for controlling plaque comprising as an active ingredient an amount of a synergistic mixture of at least one metal containing compound wherein said metal is selected from the group consisting of copper, nickel, iron, cobalt, and mixtures thereof in combination with tetradecylamine, in admixture with an acceptable oral medium compatible with said combination, said amount being effective to control plaque at the site of formation.
Claim 2
Dependent Claim
69 words
A substantially non-toxic composition for controlling plaque comprising as an active ingredient an amount of a synergistic mixture of at least one metal containing compound wherein said metal is selected from the group consisting of copper, nickel, iron, cobalt, and mixtures thereof in combination with tetradecylamine, in admixture with an acceptable oral medium compatible with said combination, said amount being effective to control plaque at the site of formation.
Claim 3
Dependent Claim
29 words
A composition as defined in claim 1 wherein the amount of said metal is at least about 0.0005 molar and of said tetradecylamine is at least about 0.005 molar.
Claim 4
Dependent Claim
27 words
A composition as defined in claim 2, said metal being present in an amount of about 0.004 molar and said tetradecylamine being present at about 0.02 molar.
Claim 5
Dependent Claim
13 words
A composition as defined in claim 1 said acceptable oral medium comprising water.
Claim 6
Independent Claim
54 words
A method for controlling plaque comprising applying to the site of said plaque, an amount of a synergistic mixture of tetradecylamine and a metal wherein said metal is selected from the group consisting of copper, iron, nickel, cobalt and mixtures thereof, said amount being effective to control said plaque at the site of formation.
Claim 7
Independent Claim
54 words
A method for controlling plaque comprising applying to the site of said plaque, an amount of a synergistic mixture of tetradecylamine and a metal wherein said metal is selected from the group consisting of copper, iron, nickel, cobalt and mixtures thereof, said amount being effective to control said plaque at the site of formation.
Claim 8
Dependent Claim
33 words
A method as defined in claim 5 wherein said antiplaque effective amount of said metal is at least about 0.0005 molar and the amount of said tetradecylamine is at least about 0.005 molar.
Claim 9
Dependent Claim
42 words
A plaque controlling mouthrinse consisting essentially of 0.02 molar tetradecylamine and 0.004 molar metal selected from the group consisting of copper, iron, nickel, cobalt and mixtures thereof, in a medium consisting essentially of 75% to 95% water and 5% to 25% ethanol.
Claim 10
Dependent Claim
42 words
A plaque controlling mouthrinse consisting essentially of 0.02 molar tetradecylamine and 0.004 molar metal selected from the group consisting of copper, iron, nickel, cobalt and mixtures thereof, in a medium consisting essentially of 75% to 95% water and 5% to 25% ethanol.
References Cited (Backward Citations)
GB654473A
Cited
GB656478A
Cited
US2876167A
Cited
US3083143A
Cited
US3175951A
Cited
DE1965046A1
Cited
US3943267A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1982-03-26 | 1982-09-25 | 1983-03-27 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1986-03-26 | 1986-09-25 | 1987-03-27 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1990-03-26 | 1990-09-25 | 1991-03-27 | $7700.00 | Window Closed / Lapsed |