US4562206A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Orally effective inotropic compounds
Assignee: Teva Branded Pharmaceutical Products R&D Inc
•
Filing: 1984-03-08
•
Granted: 1985-12-31
•
Expires: 2004-03-08
Abstract
Abstract A method for increasing cardiac contractility in a warm-blooded animal suffering from acutely depressed cardiac contractility which comprises administering to said animal an effective amount of a compound of the formula <IMAGE> wherein R is hydrogen or isobutyrate, or a pharmaceutically acceptable acid addition salt thereof.
Inventors
- 👤 Ronald R. Tuttle
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 18:16
CPC Classifications
C; C07; C07C; C07C255/00
Claims Analysis
Total Claims: 16
Claim 1
Independent Claim
20 words
A compound of the formula ##STR7## where R is hydrogen or isobutyrate, or a pharmaceutically acceptable acid addition salt thereof.
Claim 2
Dependent Claim
20 words
A compound of the formula ##STR7## where R is hydrogen or isobutyrate, or a pharmaceutically acceptable acid addition salt thereof.
Claim 3
Dependent Claim
10 words
A compound according to claim 1, wherein R is hydrogen.
Claim 4
Dependent Claim
10 words
A compound according to claim 1, wherein R is isobutyrate.
Claim 5
Dependent Claim
8 words
A compound according to claim 1, N-[2-(3,4-dihydroxyphenyl)ethyl]-1-methyl-3-(3-carbamoylphenyl)propylamine hydrochloride.
Claim 6
Dependent Claim
9 words
A compound according to claim 1, N-[2-(3,4-diisobutyryl oxyphenyl)ethyl]-1-methyl-3-(3-carbamoylphenyl)propylamine hydrochloride.
Claim 7
Independent Claim
45 words
A method for increasing cardiac contractility in a warm-blooded animal suffering from depressed cardiac contractility which comprises administering to said animal an effective amount of a compound of the formula ##STR8## wherein R is hydrogen or isobutyrate, or a pharmaceutically acceptable acid addition salt thereof.
Claim 8
Independent Claim
45 words
A method for increasing cardiac contractility in a warm-blooded animal suffering from depressed cardiac contractility which comprises administering to said animal an effective amount of a compound of the formula ##STR8## wherein R is hydrogen or isobutyrate, or a pharmaceutically acceptable acid addition salt thereof.
Claim 9
Dependent Claim
16 words
A method according to claim 6, wherein R is hydrogen and the compound is administered orally.
Claim 10
Dependent Claim
16 words
A method according to claim 6, wherein R is isobutyl and the compound is administered buccally.
Claim 11
Dependent Claim
16 words
A method according to claim 6, wherein R is hydrogen and the compound is administered intravenously.
Claim 12
Dependent Claim
16 words
A method according to claim 6, wherein R is isobutyl and the compound is administered orally.
Claim 13
Dependent Claim
37 words
A pharmaceutical composition in dosage unit form which comprises a dosage effective for the treatment of depressed cardiac contractility of a compound of the formula ##STR9## or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier.
Claim 14
Dependent Claim
37 words
A pharmaceutical composition in dosage unit form which comprises a dosage effective for the treatment of depressed cardiac contractility of a compound of the formula ##STR9## or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier.
Claim 15
Dependent Claim
37 words
A pharmaceutical composition in dosage unit form which comprises a dosage effective for the treatment of depressed cardiac contractility of a compound of the formula ##STR10## or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier.
Claim 16
Dependent Claim
37 words
A pharmaceutical composition in dosage unit form which comprises a dosage effective for the treatment of depressed cardiac contractility of a compound of the formula ##STR10## or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier.
References Cited (Backward Citations)
US3803230A
Cited
US3845123A
Cited
US3816516A
Cited
US4086272A
Cited
US3987200A
Cited
US4218470A
Cited
US4396627A
Cited
US4311706A
Cited
US4340603A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1988-12-30 | 1989-07-01 | 1989-12-31 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1992-12-30 | 1993-07-01 | 1993-12-31 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1996-12-30 | 1997-07-01 | 1997-12-31 | $7700.00 | Window Closed / Lapsed |