US4557863A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Device for collection of proteins in a urinal and method of use
Assignee: NATIONAL MANAGEMENT Corp
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Filing: 1984-04-13
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Granted: 1985-12-10
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Expires: 2004-04-13
Abstract
Abstract The invention relates to a device useful when installed in a urinal for collection of urinary proteins. The adsorbent means includes a conduit for gravity feed passage of urine streams. The conduit has permeable layers in series containing a slow releasing antimicrobial agent and an adsorbent for urinary proteins such that for collection puropses wanted proteins are adsorbed without odor or loss due to bacterial degradation.
Inventors
- 👤 Denis M. Callewaert
- 👤 Earl J. Braxton
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-31 23:15
CPC Classifications
A; A61; A61B; A61B10/00; A61B10/0045; A61B10/007; A61L; A61L28/00; A61L28/0034; A61L28/0038; Y; Y10; Y10S; Y10S435/00; Y10S435/814; Y10S435/815
Claims Analysis
Total Claims: 22
Claim 1
Independent Claim
153 words
A device for installation in a urinal useful for collection of urinary proteins, comprising an open ended columnar conduit for gravity feed passage of urine streams therethrough, and first and second urine stream permeable layers in the conduit, the first and second layers containing respectively (1) a leachable water soluble hydrophilic component comprising an antimicrobial agent and (2) an adsorbent for urinary proteins, the water soluble hydrophilic component including a water soluble antimicrobial that is leached ratably by exposure to intermittent urine streams and a water insoluble hydrophobic component that sublimes ratably to the air thereby gradually exposing the hydrophilic component for slow release, the respective rates of leaching and subliming during the service life being chosen such that the leaching of antimicrobial from the first layer into the second layer is sufficient to provide an inhibitor concentration effectively inhibiting microbial degradation of wanted proteins contained in the adsorbate of the second layer.
Claim 2
Independent Claim
153 words
A device for installation in a urinal useful for collection of urinary proteins, comprising an open ended columnar conduit for gravity feed passage of urine streams therethrough, and first and second urine stream permeable layers in the conduit, the first and second layers containing respectively (1) a leachable water soluble hydrophilic component comprising an antimicrobial agent and (2) an adsorbent for urinary proteins, the water soluble hydrophilic component including a water soluble antimicrobial that is leached ratably by exposure to intermittent urine streams and a water insoluble hydrophobic component that sublimes ratably to the air thereby gradually exposing the hydrophilic component for slow release, the respective rates of leaching and subliming during the service life being chosen such that the leaching of antimicrobial from the first layer into the second layer is sufficient to provide an inhibitor concentration effectively inhibiting microbial degradation of wanted proteins contained in the adsorbate of the second layer.
Claim 3
Dependent Claim
16 words
A device according to claim 1 where the antimicrobial agent specifically inhibits bacterial degradation of urokinase.
Claim 4
Dependent Claim
17 words
A device according to claim 1 where the antimicrobial agent comprises a water soluble salt of pyrithione.
Claim 5
Dependent Claim
13 words
A device according to claim 1 where the antimicrobial agent comprises sodium pyrithione.
Claim 6
Dependent Claim
13 words
A device according to claim 1 where the antimicrobial agent comprises sodium azide.
Claim 7
Dependent Claim
16 words
A device according to claim 1 where the first layer contains a hydrophobic component comprising p-dichlorobenzene.
Claim 8
Dependent Claim
16 words
A device according to claim 1 where the first layer contains a hydrophobic component comprising naphthalene.
Claim 9
Dependent Claim
19 words
A device according to claim 1 where the first layer comprises a homogeneous mixture of sodium pyrithione and p-dichlorobenzene.
Claim 10
Dependent Claim
40 words
A device according to claim 1 where the first layer comprises a mixture containing by weight about 5 to about 10% of antimicrobial agent and about 90 to about 95% of a hydrophobic component that sublimes on exposure to air.
Claim 11
Dependent Claim
18 words
A device according to claim 9 where the anti-microbial is sodium pyrithione and the hydrophobic component is p-dichlorobenzene.
Claim 12
Dependent Claim
14 words
A device according to claim 1 where the adsorbent is an adsorbent of urokinase.
Claim 13
Dependent Claim
13 words
A device according to claim 1 where the adsorbent is an ion-exchange resin.
Claim 14
Dependent Claim
115 words
A method of collecting urine proteins comprising the steps of installing in a urinal the device according to claim 1 comprising a conduit and first and second urine-stream permeable layers in the conduit and subjecting the permeable layers of the conduit to contact with air and intermittent flow of gravity-fed urine streams under conditions affording leaching of the antimicrobial agent from the first layers into each of the urine streams and adsorption onto the second layer of urinary proteins from each of the resulting leachate streams thereby isolating the resulting adsorbed urinary proteins as a recoverable solid phase adsorbate in the second layer in which layer the antimicrobial leachate inhibits degradation of the adsorbed protein.
Claim 15
Dependent Claim
16 words
A method according to claim 13 where the antimicrobial agent specifically inhibits the degradation of urokinase.
Claim 16
Dependent Claim
17 words
The method according to claim 13 where the hydrophilic component comprises a water soluble salt of pyrithione.
Claim 17
Dependent Claim
13 words
The method according to claim 13 where the hydrophilic component comprises sodium pyrithione.
Claim 18
Dependent Claim
13 words
The method according to claim 13 where the hydrophilic component comprises sodium azide.
Claim 19
Dependent Claim
16 words
The method according to claim 13 where the first layer contains a hydrophobic component comprising p-dichlorobenzene.
Claim 20
Dependent Claim
19 words
The method according to claim 13 where the first layer comprises a homogeneous mixture of sodium pyrithione and p-dichlorobenzene.
Claim 21
Dependent Claim
14 words
The method according to claim 13 where the adsorbent is an adsorbent of urokinase.
Claim 22
Dependent Claim
13 words
The method according to claim 13 where the adsorbent is an ion-exchange resin.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1988-12-09 | 1989-06-10 | 1989-12-10 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1992-12-09 | 1993-06-10 | 1993-12-10 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1996-12-09 | 1997-06-10 | 1997-12-10 | $7700.00 | Window Closed / Lapsed |