US4306029A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Urine storage containers with urease
Assignee: Baxter International Inc
•
Filing: 1980-04-30
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Granted: 1981-12-15
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Expires: 2000-04-30
Abstract
Abstract Growth and proliferation of bacteria may be inhibited in urine stored in a urine drainage container by placing urease in the container to generate sufficient ammonia to elevate the pH thereof to an alkaline level unfavorable for supporting microbial growth. Preferably, the urease is sealed in envelope means of semipermeable membrane which is capable of allowing diffusion of urea from urine stored in the container, while preventing substantial diffusion of the urease outwardly from the envelope means. Accordingly, the urease remains indefinitely reusable over many fillings and drainings of the container.
Inventors
- 👤 David F. Carpenter
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 00:30
CPC Classifications
A; A61; A61F; A61F5/00; A61F5/44; A61F5/441
Claims Analysis
Total Claims: 25
Claim 1
Independent Claim
62 words
The method of inhibiting the growth and proliferation of bacteria of urine stored in a urine drainage container, which comprises placing urease in said container and allowing said urine to stand in the container until sufficient ammonia is generated from urea in said urine stored in the container to elevate the pH thereof to an alkaline level unfavorable for supporting microbial growth.
Claim 2
Independent Claim
62 words
The method of inhibiting the growth and proliferation of bacteria of urine stored in a urine drainage container, which comprises placing urease in said container and allowing said urine to stand in the container until sufficient ammonia is generated from urea in said urine stored in the container to elevate the pH thereof to an alkaline level unfavorable for supporting microbial growth.
Claim 3
Dependent Claim
29 words
The method of claim 1 in which said urease is in the form of a material selected from the group consisting of jack bean powder and urease-containing extracts thereof.
Claim 4
Independent Claim
92 words
The method of inhibiting the growth and proliferation of bacteria of urine stored in a medical urine drainage container, which comprises placing urease in said container, said urease being sealed in said container within an envelope made of semipermeable membrane capable of allowing passage of urea, water, ammonia, and carbon dioxide but incapable of allowing the passage of substantial amounts of urease across said membrane, until sufficient ammonia is generated from urea of urine stored in said container to elevate the pH thereof to an alkaline level unfavorable for supporting microbial growth.
Claim 5
Independent Claim
92 words
The method of inhibiting the growth and proliferation of bacteria of urine stored in a medical urine drainage container, which comprises placing urease in said container, said urease being sealed in said container within an envelope made of semipermeable membrane capable of allowing passage of urea, water, ammonia, and carbon dioxide but incapable of allowing the passage of substantial amounts of urease across said membrane, until sufficient ammonia is generated from urea of urine stored in said container to elevate the pH thereof to an alkaline level unfavorable for supporting microbial growth.
Claim 6
Dependent Claim
17 words
The method of claim 3 in which said urease is in the form of jack bean powder.
Claim 7
Dependent Claim
18 words
The method of claim 3 in which said container includes from 7 to 20 Sumner units of urease.
Claim 8
Dependent Claim
33 words
The method of claim 3 in which sufficient urease is present in said container to raise the pH of 200 ml. of fresh urine to above 8.0 at 23° C. in one hour.
Claim 9
Dependent Claim
42 words
A urine storage container which includes therein an envelope coantaining urease, said envelope comprising semi-permeable membrane capable of allowing passage of urea, water, ammonia and carbon dioxide, but incapable of allowing the passage of substantial amounts of urease across said semipermeable membrane.
Claim 10
Dependent Claim
42 words
A urine storage container which includes therein an envelope coantaining urease, said envelope comprising semi-permeable membrane capable of allowing passage of urea, water, ammonia and carbon dioxide, but incapable of allowing the passage of substantial amounts of urease across said semipermeable membrane.
Claim 11
Dependent Claim
66 words
A urine drainage container comprising a flexible drainage tube, a urinary drainage catheter adaptor attached to one end thereof, and a urine storage container attached to the other end thereof, the improvement comprising, a quantity of urease positioned within said storage container sufficient to elevate the pH of 200 ml of urine stored at 23° C. in said container to above pH 8.0 in one hour.
Claim 12
Dependent Claim
66 words
A urine drainage container comprising a flexible drainage tube, a urinary drainage catheter adaptor attached to one end thereof, and a urine storage container attached to the other end thereof, the improvement comprising, a quantity of urease positioned within said storage container sufficient to elevate the pH of 200 ml of urine stored at 23° C. in said container to above pH 8.0 in one hour.
Claim 13
Dependent Claim
31 words
The container of claim 8 in which said storage container is a flexible, plastic bag defining means for intermittently draining said urine by a route other than said flexible drainage tube.
Claim 14
Dependent Claim
17 words
The container of claim 8 in which said urease is in the form of jack bean powder.
Claim 15
Dependent Claim
20 words
The container of claim 8 in which 7 to 20 Sumner units of urease are present in said storage container.
Claim 16
Dependent Claim
83 words
A urine drainage container having access means for placing urine therein and removing urine therefrom, said drainage container carrying in its interior a quantity of urease sealed in envelope means comprising semipermeable membrane which is capable of allowing inward diffusion of urea and water from urine stored in said container and outward diffusion of ammonia and carbon dioxide, while preventing substantial diffusion of said urease outwardly from said envelope, whereby stored urine may be drained from said container without loss of said urease.
Claim 17
Dependent Claim
83 words
A urine drainage container having access means for placing urine therein and removing urine therefrom, said drainage container carrying in its interior a quantity of urease sealed in envelope means comprising semipermeable membrane which is capable of allowing inward diffusion of urea and water from urine stored in said container and outward diffusion of ammonia and carbon dioxide, while preventing substantial diffusion of said urease outwardly from said envelope, whereby stored urine may be drained from said container without loss of said urease.
Claim 18
Dependent Claim
29 words
The urine drainage container of claim 12 which is a flexible plastic envelope defining means for intermittently draining said urine by a route other than through said access means.
Claim 19
Dependent Claim
36 words
The urine drainage container of claim 12 in which sufficient urease is present to elevate the pH of 200 ml of fresh urine stored at 23° C. in said container to above 8.0 in one hour.
Claim 20
Dependent Claim
21 words
The container of claim 12 in which from 7 to 20 Sumner units of urease are present in said drainage container.
Claim 21
Dependent Claim
16 words
The urine drainage container of claim 12 in which said semipermeable membrane is a cellulose-based membrane.
Claim 22
Dependent Claim
17 words
The urine drainage container of claim 16 in which said semipermeable membrane is made of cupraammonium cellulose.
Claim 23
Dependent Claim
19 words
The urine drainage container of claim 12 in which said urease is in the form of jack bean powder.
Claim 24
Dependent Claim
63 words
A urine drainage container having access means for placing urine therein, said drainage container carrying in its interior a sufficient quantity of materials selected from a group consisting of jack bean powder and urease-containing extracts of jack bean powder to cause 200 ml of fresh urine stored at 23° C. in said container to achieve a pH of above 8.0 in one hour.
Claim 25
Dependent Claim
63 words
A urine drainage container having access means for placing urine therein, said drainage container carrying in its interior a sufficient quantity of materials selected from a group consisting of jack bean powder and urease-containing extracts of jack bean powder to cause 200 ml of fresh urine stored at 23° C. in said container to achieve a pH of above 8.0 in one hour.
References Cited (Backward Citations)
US3635798A
Cited
US3865726A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-12-14 | 1985-06-15 | 1985-12-15 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-12-14 | 1989-06-15 | 1989-12-15 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-12-14 | 1993-06-15 | 1993-12-15 | $7700.00 | Window Closed / Lapsed |