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US4554256A Expired / Lapsed US ⏱️ 0.0 years remaining

Antigen associated with early detection of mammalian pregnancy

Assignee: Idaho Research Foundation Inc
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Filing: 1983-07-21
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Granted: 1985-11-19
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Expires: 2003-07-21
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Abstract

Abstract Early pregnancy can be determined by detection of a protein in serum, which protein is associated with the placental membrane. The protein is characterized by having an approximate molecular weight of 47,000 to 53,000 and an isoelectric point of from about 4.0-4.4.

Inventors

  • 👤 R. Garth Sasser
  • 👤 William C. Hamilton

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-08 07:48
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/68; G01N33/689; G01N2800/00; G01N2800/36; G01N2800/368; Y; Y10; Y10S; Y10S436/00; Y10S436/804; Y10S436/811; Y10S436/814; Y10S436/815

Claims Analysis

Total Claims: 7
Claim 1
Independent Claim 88 words
A method for detecting pregnancy of a bovine or ovine host, said method comprising: combining serum or blood from said host with antibody which specifically binds to Protein B, said Protein B being characterized by having a molecular weight in the range of about 47-53 kD, an isoelectric point in the range of about 4.0-4.4 and isolatable from bovine placental membrane homogenates, and detecting complex formation between said antibody and an antigen present in said blood or serum, wherein complex formation is indicative of pregnancy of said host.
Claim 2
Independent Claim 88 words
A method for detecting pregnancy of a bovine or ovine host, said method comprising: combining serum or blood from said host with antibody which specifically binds to Protein B, said Protein B being characterized by having a molecular weight in the range of about 47-53 kD, an isoelectric point in the range of about 4.0-4.4 and isolatable from bovine placental membrane homogenates, and detecting complex formation between said antibody and an antigen present in said blood or serum, wherein complex formation is indicative of pregnancy of said host.
Claim 3
Dependent Claim 22 words
A method according to claim 1, wherein said complex formation is determined by measuring the presence or absence of labelled Protein B.
Claim 4
Dependent Claim 24 words
A method according to claim 1, wherein said complex formation is determined by measuring the presence or absence of labelled antibody to Protein B.
Claim 5
Dependent Claim 11 words
A method according to claim 1, wherein said host is bovine.
Claim 6
Dependent Claim 11 words
A method according to claim 1 wherein said host is bovine.
Claim 7
Dependent Claim 11 words
A method according to claim 1, wherein said host is ovine.

References Cited (Backward Citations)

US4191533A Cited
US4217339A Cited
US4269825A Cited
US4297343A Cited
US4302385A Cited
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US4402872A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1988-11-18 1989-05-20 1989-11-19 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1992-11-18 1993-05-20 1993-11-19 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1996-11-18 1997-05-20 1997-11-19 $7700.00 Window Closed / Lapsed

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