US4549807A
Expired / Lapsed
US
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Process for measuring fluorescence
Assignee: Nokia Bell Labs
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Filing: 1983-10-07
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Granted: 1985-10-29
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Expires: 2003-10-07
Abstract
Abstract Fluorescent measurements are taken utilizing a Raman enhancing surface by a method which allows reduction or essentially complete elimination of interference by fluorescence quenchers. In particular, the fluorescent medium to be measured is interacted with a Raman enhancing surface. Through this interaction between the Raman enhancing surface and the fluorescing species, fluorescence quenching is eliminated. The quenching is particularly significant in analytical procedures such as those involved in chromatography and medical testing.
Inventors
- 👤 Timothy D. Hoffmaster
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-27 12:38
CPC Classifications
G; G01; G01N; G01N21/00; G01N21/62; G01N21/63; G01N21/64; G01N21/645; G01N21/648; G01N21/6428; G01N2021/6432; G01N2021/6439
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
64 words
A process for determining the presence of a fluorescing species in a condensed phase sample that interacts with an entity that quenches said fluorescence, said process comprising the steps of exciting said fluorescing species with electromagnetic radiation and monitoring the electromagnetic radiation emanating from said sample wherein said species in said sample is allowed to interact with a Raman enhancing surface during said determination.
Claim 2
Dependent Claim
64 words
A process for determining the presence of a fluorescing species in a condensed phase sample that interacts with an entity that quenches said fluorescence, said process comprising the steps of exciting said fluorescing species with electromagnetic radiation and monitoring the electromagnetic radiation emanating from said sample wherein said species in said sample is allowed to interact with a Raman enhancing surface during said determination.
Claim 3
Dependent Claim
13 words
The process of claim 1 wherein said monitoring is accomplished with a photomultiplier.
Claim 4
Dependent Claim
11 words
The process of claim 1 wherein said sample is a liquid.
Claim 5
Dependent Claim
11 words
The process of claim 1 wherein said sample is a solid.
Claim 6
Dependent Claim
12 words
The process of claim 1 wherein said exciting electromagnetic radiation is coherent.
Claim 7
Dependent Claim
12 words
The process of claim 1 wherein said exciting electromagnetic radiation is incoherent.
Claim 8
Dependent Claim
23 words
The process of claim 1 wherein said Raman enhancing surface comprises a metal chosen from the group consisting of silver, copper, and gold.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1988-10-28 | 1989-04-29 | 1989-10-29 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1992-10-28 | 1993-04-29 | 1993-10-29 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1996-10-28 | 1997-04-29 | 1997-10-29 | $7700.00 | Window Closed / Lapsed |