Patent US479569A successfully refreshed from Google Patents.
Patent US4547464A successfully refreshed from Google Patents.
US4547464A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Fetal pulmonary maturity test
Assignee: Individual
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Filing: 1984-03-12
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Granted: 1985-10-15
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Expires: 2004-03-12
Abstract
Abstract A quick and inexpensive test for the detection of fetal pulmonary maturity comprising the steps of acidifying a given volume of amniotic fluid, adding a given volume of an ether, agitating and observing the number of bubbles existing in the ether layer. The number of bubbles existing in the ether layer after a certain observational period may be correlated with the existence of pulmonary immaturity in a fetus.
Inventors
- 👤 Michael Socol
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 04:09
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/92; G01N13/00; G01N13/02; G01N2013/0241; G01N2013/025; Y; Y10; Y10S; Y10S436/00; Y10S436/907
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
130 words
A method for testing for fetal pulmonary immaturity comprising the steps of withdrawing amniotic fluid from a pregnant mother, acidifying a predetermined amount of said amniotic fluid, adding an approximately equal volume of an alkyl ether to form a testing solution having an ether layer over an amniotic fluid layer; agitating said testing solution sufficiently to create a multitude from about 200 to 300 of bubbles in said ether layer, permitting said agitated testing solution to rest for an observational period of at least 2 minutes, observing the number of bubbles remaining in said ether layer after the passage of said observational period, and from said number of remaining bubbles predicting the maturity or immaturity of the fetal pulmonary function of the fetus within the womb of the pregnant mother.
Claim 2
Independent Claim
130 words
A method for testing for fetal pulmonary immaturity comprising the steps of withdrawing amniotic fluid from a pregnant mother, acidifying a predetermined amount of said amniotic fluid, adding an approximately equal volume of an alkyl ether to form a testing solution having an ether layer over an amniotic fluid layer; agitating said testing solution sufficiently to create a multitude from about 200 to 300 of bubbles in said ether layer, permitting said agitated testing solution to rest for an observational period of at least 2 minutes, observing the number of bubbles remaining in said ether layer after the passage of said observational period, and from said number of remaining bubbles predicting the maturity or immaturity of the fetal pulmonary function of the fetus within the womb of the pregnant mother.
Claim 3
Dependent Claim
42 words
The method of claim 1 wherein one milliliter of amniotic fluid is mixed with a drop of an inorganic acid to form an acidified amniotic fluid solution; and approximately 1.5 milliliters of diethyl ether is added to said acidified amniotic fluid solution.
Claim 4
Dependent Claim
28 words
The method of claim 1 wherein the test solution is agitated by briskly tapping the container holding the said test solution 3 or 4 times with a finger.
Claim 5
Dependent Claim
33 words
The method of claim 1 wherein the prediction of fetal pulmonary maturity is accomplished through the observation of no more than five bubbles in the ether layer after passage of said observation period.
Claim 6
Dependent Claim
17 words
The method of claim 1 wherein said observational period is 2 minutes, 5 minutes or 10 minutes.
Claim 7
Independent Claim
154 words
A method for testing for fetal pulmonary immaturity comprising the steps of: (1) withdrawing amniotic fluid from a pregnant mother; (2) adding one drop of hydrochloric acid to acidify approximately 1.0 milliliter of said amniotic fluid in a test tube; (3) adding approximately 1.5 milliliters of ethyl ether to form a testing solution in said test tube having an ether layer over an amniotic fluid layer; (4) agitating said testing solution by tapping said test tube to create a multitude from about 200 to 300 of bubbles in said ether layer; (5) permitting said agitated testing solution to rest for an observational period of at least 2 minutes; (6) observing the number of bubbles remaining in said ether layer after the passage of said observational period; and (7) from said number of remaining bubbles predicting the maturity or immaturity of the fetal pulmonary function of the fetus within the womb of the pregnant mother.
Claim 8
Independent Claim
154 words
A method for testing for fetal pulmonary immaturity comprising the steps of: (1) withdrawing amniotic fluid from a pregnant mother; (2) adding one drop of hydrochloric acid to acidify approximately 1.0 milliliter of said amniotic fluid in a test tube; (3) adding approximately 1.5 milliliters of ethyl ether to form a testing solution in said test tube having an ether layer over an amniotic fluid layer; (4) agitating said testing solution by tapping said test tube to create a multitude from about 200 to 300 of bubbles in said ether layer; (5) permitting said agitated testing solution to rest for an observational period of at least 2 minutes; (6) observing the number of bubbles remaining in said ether layer after the passage of said observational period; and (7) from said number of remaining bubbles predicting the maturity or immaturity of the fetal pulmonary function of the fetus within the womb of the pregnant mother.
Claim 9
Dependent Claim
33 words
The method of claim 6 wherein the prediction of fetal pulmonary maturity is accomplished through the observation of no more than five bubbles in the ether layer after passage of said observation period.
Claim 10
Dependent Claim
17 words
The method of claim 6 wherein said observational period is 2 minutes, 5 minutes or 10 minutes.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1988-10-14 | 1989-04-15 | 1989-10-15 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1992-10-14 | 1993-04-15 | 1993-10-15 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1996-10-14 | 1997-04-15 | 1997-10-15 | $7700.00 | Window Closed / Lapsed |