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US4543952A Expired / Lapsed US ⏱️ 0.0 years remaining

Flexible copolymers of p-(hydroxyalkoxy)benozic acid and pliant surgical products, particularly monofilament surgical sutures, therefrom

Assignee: Ethicon Inc
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Filing: 1983-09-14
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Granted: 1985-10-01
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Expires: 2003-09-14
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Abstract

Abstract Novel flexible polyesters comprising copolymers made from an alkylene oxybenzoate and one of the following sequences: (1) an alkylene, 2-alkenyl- (or alkyl-) succinate; (2) an alkylene dimerate (from the dimer of a long chain unsaturated fatty acid), and pliant surgical products, particularly monofilament surgical sutures, therefrom.

Inventors

  • 👤 Shalaby W. Shalaby
  • 👤 Donald F. Koelmel

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-01 23:08
CPC Classifications
C; C08; C08G; C08G63/00; C08G63/66

Claims Analysis

Total Claims: 15
Claim 1
Independent Claim 191 words
A surgical filament comprising a random copolymer of the formula: ##STR5## wherein m represents a number having an average value of from 2 to 6, wherein x and y represent numbers having average values such that the units represented by A comprise from about 1 to about 50 weight percent of the copolymer, the remainder comprising the alkyleneoxy benzoate units, and wherein the A units represent at least one of the following units (1) or (2): --CO--CHR--CH.sub.2 --CO--O--CH.sub.2)--O]-- (1) wherein n represents a number having an average value of from 2 to 12, and wherein R represents alkyl or 2-alkenyl of from 8 to 24 carbon atoms; or --CO--DA--CO--O(CH.sub.2)--O-- (2) wherein DA represents the residue after removal of the carboxyl groups of a dimer acid of long chain unsaturated fatty acid, said residue having an approximate formula of C 34 H 66 , and wherein n represents a number having an average value of 2 to 12; wherein said filament is characterized by the following physical properties: Knot strength greater than about 25×10 3 psi Tensile strength greater than about 45×10 3 psi Young's Modulus less than about 250×10 3 psi.
Claim 2
Dependent Claim 191 words
A surgical filament comprising a random copolymer of the formula: ##STR5## wherein m represents a number having an average value of from 2 to 6, wherein x and y represent numbers having average values such that the units represented by A comprise from about 1 to about 50 weight percent of the copolymer, the remainder comprising the alkyleneoxy benzoate units, and wherein the A units represent at least one of the following units (1) or (2): --CO--CHR--CH.sub.2 --CO--O--CH.sub.2)--O]-- (1) wherein n represents a number having an average value of from 2 to 12, and wherein R represents alkyl or 2-alkenyl of from 8 to 24 carbon atoms; or --CO--DA--CO--O(CH.sub.2)--O-- (2) wherein DA represents the residue after removal of the carboxyl groups of a dimer acid of long chain unsaturated fatty acid, said residue having an approximate formula of C 34 H 66 , and wherein n represents a number having an average value of 2 to 12; wherein said filament is characterized by the following physical properties: Knot strength greater than about 25×10 3 psi Tensile strength greater than about 45×10 3 psi Young's Modulus less than about 250×10 3 psi.
Claim 3
Dependent Claim 22 words
A filament as in claim 1 having a surgical needle attached to at least one end and useful as a surgical suture.
Claim 4
Dependent Claim 11 words
A filament of claim 1 or 2 in a sterile condition.
Claim 5
Dependent Claim 17 words
A filament of claim 1 wherein the A units comprise about 10-30% by weight of the copolymer.
Claim 6
Dependent Claim 7 words
A filament of claim 1 wherein m=4.
Claim 7
Dependent Claim 9 words
A filament of claim 1 wherein n=4 or 6.
Claim 8
Dependent Claim 16 words
A filament of claim 1 wherein R has a chain length of about 16-24 carbon atoms.
Claim 9
Dependent Claim 14 words
A filament of claim 1 wherein R has a chain length of about 18.
Claim 10
Dependent Claim 9 words
A filament of claim 1 wherein R is 2-alkenyl.
Claim 11
Dependent Claim 12 words
A woven or knitted surgical fabric comprised of filaments of claim 1.
Claim 12
Dependent Claim 10 words
A fabric of claim 10 in a seamless tubular construction.
Claim 13
Dependent Claim 20 words
A method of closing a wound by approximating and securing the wound tissue with a surgical fiber of claim 1.
Claim 14
Dependent Claim 161 words
A solid surgical aid molded or machined from a copolymer of the formula: ##STR6## wherein m represents a number having an average value of from 2 to 6, wherein x and y represent numbers having average values such that the units represented by A comprise from a about 1 to about 50 weight percent of the copolymer, the remainder comprising the alkyleneoxy benzoate units, and wherein the A units represent at least one of the following units (1) or (2): --CO--CHR--CH.sub.2 --CO--O--CH.sub.2)--O]-- (1) wherein n represents a number having an average value of from 2 to 12, and wherein R represents alkyl or 2-alkenyl of from 8 to 24 carbon atoms; or --CO--DA--CO--O(CH.sub.2)--O-- (2) wherein DA represents the residue after removal of the carboxyl groups of a dimer acid of long chain unsaturated fatty acid, said residue having an approximate formula of C 34 H 66 , and wherein n represents a number having an average value of 2 to 12.
Claim 15
Dependent Claim 161 words
A solid surgical aid molded or machined from a copolymer of the formula: ##STR6## wherein m represents a number having an average value of from 2 to 6, wherein x and y represent numbers having average values such that the units represented by A comprise from a about 1 to about 50 weight percent of the copolymer, the remainder comprising the alkyleneoxy benzoate units, and wherein the A units represent at least one of the following units (1) or (2): --CO--CHR--CH.sub.2 --CO--O--CH.sub.2)--O]-- (1) wherein n represents a number having an average value of from 2 to 12, and wherein R represents alkyl or 2-alkenyl of from 8 to 24 carbon atoms; or --CO--DA--CO--O(CH.sub.2)--O-- (2) wherein DA represents the residue after removal of the carboxyl groups of a dimer acid of long chain unsaturated fatty acid, said residue having an approximate formula of C 34 H 66 , and wherein n represents a number having an average value of 2 to 12.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1988-09-30 1989-04-01 1989-10-01 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1992-09-30 1993-04-01 1993-10-01 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1996-09-30 1997-04-01 1997-10-01 $7700.00 Window Closed / Lapsed

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