US4533546A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Antiinflammatory analgesic gelled ointments
Assignee: Pfizer Japan Inc
•
Filing: 1984-05-31
•
Granted: 1985-08-06
•
Expires: 2004-05-31
Abstract
Abstract An antiinflammatory analgesic gelled ointment comprising a phenylacetic acid type antiinflammatory analgesic agent, a carboxyvinyl polymer in an amount sufficient for gel formation, a water-soluble organic amine, a lower alcohol and water and having a pH in the range of from 7.0 to 9.0.
Inventors
- 👤 Ikuo Kishi
- 👤 Hideo Yoshida
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-31 11:33
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0014; A61K31/00; A61K31/185; A61K31/19; A61P; A61P25/00; A61P25/04; A61P29/00
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
119 words
An antiinflammatory analgesic gelled ointment consisting essentially of (a) 0.5 to 8% by weight of 4-biphenylylacetic acid, (b) 0.5 to 5% by weight of a carboxyvinyl polymer, having a molecular weight in the range of 1,000,000 to 3,000,000, (c) 0.5 to 15% by weight of a water-soluble organic amine selected from mono-, di- and tri-lower alkanol amines, (d) 5 to 50% by weight of a lower alkanol selected from the group consisting of methanol, ethanol, propanol, isopropanol, butanol, tert-butanol and amyl alcohol, and (e) water in an amount sufficient to make up the balance of the ointment, the amount of the organic amine being such that the ointment has a pH in the range of from 7.0 to 9.0.
Claim 2
Dependent Claim
119 words
An antiinflammatory analgesic gelled ointment consisting essentially of (a) 0.5 to 8% by weight of 4-biphenylylacetic acid, (b) 0.5 to 5% by weight of a carboxyvinyl polymer, having a molecular weight in the range of 1,000,000 to 3,000,000, (c) 0.5 to 15% by weight of a water-soluble organic amine selected from mono-, di- and tri-lower alkanol amines, (d) 5 to 50% by weight of a lower alkanol selected from the group consisting of methanol, ethanol, propanol, isopropanol, butanol, tert-butanol and amyl alcohol, and (e) water in an amount sufficient to make up the balance of the ointment, the amount of the organic amine being such that the ointment has a pH in the range of from 7.0 to 9.0.
Claim 3
Dependent Claim
19 words
A gelled ointment according to claim 1 which has a pH in the range of from 7.0 to 8.0.
Claim 4
Dependent Claim
14 words
A gelled ointment according to claim 1 wherein the water-soluble organic amine is diisopropanolamine.
Claim 5
Dependent Claim
17 words
A gelled ointment according to claim 1 wherein the lower alcohol is methanol, ethanol, propanol or isopropanol.
Claim 6
Dependent Claim
13 words
A gelled ointment according to claim 4 wherein the lower alcohol is ethanol.
Claim 7
Dependent Claim
33 words
A gelled ointment according to claim 1 which contains 5.0 to 50.0% by weight of the lower alcohol and 30.0 to 85.0% by weight of water based on the weight of the ointment.
Claim 8
Dependent Claim
72 words
A gelled ointment according to claim 1 comprising 0.5 to 8.0% by weight of 4-biphenylylacetic acid, 0.5 to 3.0 by weight of the carboxyvinyl polymer, 0.5 to 10.0% by weight of the water-soluble organic amine, 10.0 to 40.0% by weight of the lower alcohol and 40.0 to 80.0% by weight of water, all based on the weight of the ointment, and having a pH in the range of from 7.0 to 8.0.
References Cited (Backward Citations)
US3749773A
Cited
US3784704A
Cited
US4309414A
Cited
BE886487A
Cited
FR2482456A1
Cited
US4393076A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1988-08-05 | 1989-02-04 | 1989-08-06 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1992-08-05 | 1993-02-04 | 1993-08-06 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1996-08-05 | 1997-02-04 | 1997-08-06 | $7700.00 | Window Closed / Lapsed |