Patent US4532241A successfully refreshed from Google Patents.
US4532241A
Expired / Lapsed
US
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8,10-Dideazaminopterins
Assignee: SRI International Inc
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Filing: 1984-01-17
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Granted: 1985-07-30
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Expires: 2004-01-17
Abstract
Abstract 10-Alkyl-8,10-dideazaminopterins of the formula ##STR1## where R is hydrogen or alkyl of 1 to about 8 carbon and their carboxylate and acid addition salts are described. These compounds exhibit antineoplastic activity that is similar to, but more effective than, methotrexate.
Inventors
- 👤 Joseph I. DeGraw
- 👤 Lawrence F. Kelly
- 👤 Francis M. Sirotnak
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 03:24
CPC Classifications
C; C07; C07D; C07D471/00; C07D471/02; C07D471/04
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
1 words
10-Ethyl-8,10-dideazaminopterin.
Claim 2
Dependent Claim
1 words
10-Ethyl-8,10-dideazaminopterin.
Claim 3
Dependent Claim
20 words
An antineoplastic composition comprising a therapeutically effective amount of 10-ethyl-8,10-dideazaminopterin or a salt thereof combined with a pharmaceutically acceptable carrier.
Claim 4
Dependent Claim
20 words
An antineoplastic composition comprising a therapeutically effective amount of 10-ethyl-8,10-dideazaminopterin or a salt thereof combined with a pharmaceutically acceptable carrier.
Claim 5
Independent Claim
24 words
A method of inhibiting neoplastic growth in a living animal comprising administering a therapeutically effective amount of 10-ethyl-8,10-dideazaminopterin or a pharmaceutically acceptable salt thereof.
Claim 6
Independent Claim
24 words
A method of inhibiting neoplastic growth in a living animal comprising administering a therapeutically effective amount of 10-ethyl-8,10-dideazaminopterin or a pharmaceutically acceptable salt thereof.
References Cited (Backward Citations)
US4460591A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1988-07-29 | 1989-01-28 | 1989-07-30 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1992-07-29 | 1993-01-28 | 1993-07-30 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1996-07-29 | 1997-01-28 | 1997-07-30 | $7700.00 | Window Closed / Lapsed |