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Manufacture of highlighted intagliated articles

Assignee: Syngenta Ltd
•
Filing: 1983-05-31
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Granted: 1985-06-11
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Expires: 2003-05-31
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Abstract

Abstract Process for manufacturing colored solid articles, e.g. pharmaceutical tablets, bearing at least one highlighted intagliation, which comprises (1) either (A) applying to said articles a film coating suspension comprising at least one defined optically anisotropic substance and at least one film coating agent, or (B) applying to said articles a suspension comprising at least one defined optically anisotropic substance but no film coating agent, and then (2) spraying the resulting articles with a solvent, and in which both of the steps (1) and (2) are carried out in a conventional film coating apparatus.

Inventors

  • 👤 Brian L. Corfield
  • 👤 Raymond C. Rowe

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-07 16:32
CPC Classifications
B; B05; B05D; B05D5/00; B05D5/06; A; A23; A23G; A23G3/00; A23G3/02; A23G3/28; A23G3/34; A23G3/50; A23G3/54; A61; A61K; A61K9/00; A61K9/20; A61K9/2072; A61K9/28; B05D2258/00

Claims Analysis

Total Claims: 11
Claim 1
Independent Claim 229 words
In a process for the manufacture of colored solid articles bearing at least one highlighted intagliation, which comprises: either (A) applying to colored intagliated articles, which themselves may be uncoated or film coated, a film coating suspension comprising at least one optically anisotropic substance having a minimum refractive index not greater than 2.00 and at least one film coating agent, the application being carried out in a conventional film coating apparatus in such a way that a rubbing action takes place between the articles being coated; or (B) applying to colored intagliated articles, which themselves may be uncoated or film coated, a suspension comprising at least one optically anisotropic substance having a minimum refractive index not greater than 2.00, but no film coating agent, and the application being carried out in a conventional film coating apparatus in such a way that a rubbing action takes place between the articles being coated; the improvement whereby better contrast is obtained between the highlighted intagliation and the rest of the surface of the article, said improvement comprising spraying the coloured solid articles bearing at least one highlighted intagliation obtained per (A) or (B) with a solvent in a conventional film coating apparatus in such a way that a rubbing action takes place between the said articles, whereby the contrast between the highlighted intagliation and the rest of the article surface is improved.
Claim 2
Dependent Claim 229 words
In a process for the manufacture of colored solid articles bearing at least one highlighted intagliation, which comprises: either (A) applying to colored intagliated articles, which themselves may be uncoated or film coated, a film coating suspension comprising at least one optically anisotropic substance having a minimum refractive index not greater than 2.00 and at least one film coating agent, the application being carried out in a conventional film coating apparatus in such a way that a rubbing action takes place between the articles being coated; or (B) applying to colored intagliated articles, which themselves may be uncoated or film coated, a suspension comprising at least one optically anisotropic substance having a minimum refractive index not greater than 2.00, but no film coating agent, and the application being carried out in a conventional film coating apparatus in such a way that a rubbing action takes place between the articles being coated; the improvement whereby better contrast is obtained between the highlighted intagliation and the rest of the surface of the article, said improvement comprising spraying the coloured solid articles bearing at least one highlighted intagliation obtained per (A) or (B) with a solvent in a conventional film coating apparatus in such a way that a rubbing action takes place between the said articles, whereby the contrast between the highlighted intagliation and the rest of the article surface is improved.
Claim 3
Dependent Claim 36 words
A process as claimed in claim 1 in which the coloured intagliated article is a pharmaceutical or veterinary unit dosage form or a piece of sugar confectionery having approximately the same dimensions as a pharmaceutical tablet.
Claim 4
Dependent Claim 22 words
A process as claimed in claim 2 in which the pharmaceutical or veterinary unit dosage form is a pharmaceutical or veterinary tablet.
Claim 5
Dependent Claim 92 words
A process as claimed in claim 1 in which the said coloured solid articles bearing at least one highlighted intagliation either have no film coating agent on their outer surface or they have a relatively water-soluble film coating agent on their outer surface, and in which the said solvent used in step (2) is (a) water, (b) a mixture of water and a (1-4C)alkanol, (c) a mixture of a polyhalogenated (1-4C)alkane and a (1-4C)alkanol, or (d) a mixture of solvent (c) and a dialkyl ketone of not more than 6 carbon atoms.
Claim 6
Dependent Claim 17 words
A process as claimed in claim 4 in which the said solvent contains at least one humectant.
Claim 7
Dependent Claim 22 words
A process as claimed in claim 5 in which the humectant is glycerol, propylene glycol, or a low molecular weight polyethylene glycol.
Claim 8
Dependent Claim 13 words
A process as claimed in claim 4 in which the solvent is water.
Claim 9
Dependent Claim 75 words
A process as claimed in claim 1 in which the said coloured solid articles bearing at least one highlighted intagliation have a relatively water-insoluble film coating agent on their outer surface, and in which the said solvent used in step (2) is (e) a polyhalogenated (1-4C)alkane, (f) a dialkyl ketone of not more than 6 carbon atoms, (g) a mixture of solvents (e) and (f), or (h) a mixture of solvent (g) and a (1-4C)alkanol.
Claim 10
Dependent Claim 28 words
A process as claimed in claim 8 in which the said solvent contains at least one plasticiser which is suitable for the said relatively water-insoluble film coating agent.
Claim 11
Dependent Claim 27 words
A process as claimed in claim 9 in which the plasticiser is a di-(1-4C)alkyl phthalate, an ester of glycerol with an alkanoic acid, or a vegetable oil.

References Cited (Backward Citations)

EP0060023A1 Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1988-06-10 1988-12-10 1989-06-11 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1992-06-10 1992-12-10 1993-06-11 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1996-06-10 1996-12-10 1997-06-11 $7700.00 Window Closed / Lapsed

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