US4522786A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Multilayered test device for detecting analytes in liquid test samples
Assignee: Dade Behring Inc
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Filing: 1983-08-10
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Granted: 1985-06-11
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Expires: 2003-08-10
Abstract
Abstract A foraminous septum, the foramina of which are filled with a thermally sensitive material, is used to form a barrier layer to separate two functional layers of a multilayered test device. At assay temperature, the septum prevents fluid communication between the functional layers. When heated, the thermally sensitive material melts allowing fluid communication between the functional layers. The barrier layer can be used to control incubation and reaction times in multilayered test devices.
Inventors
- 👤 Richard C. Ebersole
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-04 07:12
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/52; G01N33/525; Y; Y10; Y10S; Y10S435/00; Y10S435/805
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
86 words
In a multilayered test device for the assay of analytes in test liquids, said device comprising at least two liquid permeable functional layers superposed upon one another, said layers being in liquid communication, the improvement comprising: a barrier layer separating said layers, said barrier layer comprising a chemically inert, liquid insoluble, foraminous septum, the foramina of which are filled with a thermally sensitive material which is liquid impermeable at assay temperature, but capable of melting when heated, thereby providing rapid liquid communication between said functional layers.
Claim 2
Dependent Claim
86 words
In a multilayered test device for the assay of analytes in test liquids, said device comprising at least two liquid permeable functional layers superposed upon one another, said layers being in liquid communication, the improvement comprising: a barrier layer separating said layers, said barrier layer comprising a chemically inert, liquid insoluble, foraminous septum, the foramina of which are filled with a thermally sensitive material which is liquid impermeable at assay temperature, but capable of melting when heated, thereby providing rapid liquid communication between said functional layers.
Claim 3
Dependent Claim
23 words
The test device of claim 1 wherein the thermally sensitive material is selected from the group consisting of agar, agarose, gelatin, and collagen.
Claim 4
Dependent Claim
13 words
The test device of claim 2 wherein the thermally sensitive material is gelatin.
Claim 5
Dependent Claim
21 words
The test device of claim 1 wherein the thermally sensitive material is a vinyl-benzene, polyethylene oxide or polyvinyl alcohol synthetic polymer.
Claim 6
Dependent Claim
28 words
The test device of claim 1 wherein the foraminous septum is a net or woven material selected from the group consisting of nylon, synthetic polyester and natural fiber.
Claim 7
Dependent Claim
12 words
The test device of claim 5 wherein the woven material is nylon.
Claim 8
Dependent Claim
40 words
The test device of claim 1 wherein the foraminous septum is a mat made of randomly arranged fibers selected from the group consisting of paper, glass, fur, silk, wool, hemp, jute, linen, metal, nylon, polyester, cellulose acetate, quartz and rubber.
Claim 9
Dependent Claim
11 words
The test device of claim 7 wherein the fiber is paper.
Claim 10
Dependent Claim
15 words
The test device of claim 1 wherein the foraminous septum is a uniform pore membrane.
Claim 11
Dependent Claim
17 words
The test device of claim 9 wherein the membrane is a polycarbonate film etched with nuclear radiation.
Claim 12
Dependent Claim
22 words
The test device of claim 1 wherein the foraminous septum is an etched polycarbonate film and the thermally sensitive material is gelatin.
Claim 13
Dependent Claim
13 words
The test device of claim 11 wherein the gelatin is about 5% (w/v).
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1988-06-10 | 1988-12-10 | 1989-06-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1992-06-10 | 1992-12-10 | 1993-06-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1996-06-10 | 1996-12-10 | 1997-06-11 | $7700.00 | Window Closed / Lapsed |