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US4519239A Expired / Lapsed US ⏱️ 0.0 years remaining

Apparatus for determining the flow shear stress of suspensions in particular blood

Assignee: DR HOLGER KIESEWETTER STOCKWIESE 44 D-6650 HOMBURG-KIRRBERG/SAAR GERMANY
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Filing: 1983-05-11
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Granted: 1985-05-28
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Expires: 2003-05-11
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Abstract

Abstract The invention concerns a measuring apparatus for checking and determining the flow shear stress of certain suspensions, principally blood, by a static or dynamic method and to thereby plot the viscosity of the suspension. The apparatus employs an internal measuring chamber comprised of a passage arrangement to simulate the natural microcirculation area wherein a network of capillary passages diverge from a main passage, with at least two of the capillary passages of different lengths, with a length ratio that can range from 3:1 to 15:1, with those capillaries connected to a source of variable pressure and extending past a detector unit.

Inventors

  • 👤 Holger Kiesewetter
  • 👤 Friedrich Jung
  • 👤 Hartmut Radtke
  • 👤 Reinhard Witt

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 13:45
CPC Classifications
G; G01; G01N; G01N11/00; G01N11/02; G01N11/04; G01N11/08; G01N33/00; G01N33/48; G01N33/483; G01N33/487; G01N33/49

Claims Analysis

Total Claims: 21
Claim 1
Independent Claim 102 words
Apparatus for determining the flow shear stress of suspensions, in particular blood, comprising a means having a main passage therein and a network of capillary passages, said capillary passages diverging from the main passage at an angle characterized by at least two capillary passages of which the ratio of the length L l of the long passage and the length L k of the short passage lies in a range of 3:1 to 15:1 and which are connected to a means for producing a variable pressure differential, and by a detector system with which the flowing of the fluid can be detected.
Claim 2
Dependent Claim 102 words
Apparatus for determining the flow shear stress of suspensions, in particular blood, comprising a means having a main passage therein and a network of capillary passages, said capillary passages diverging from the main passage at an angle characterized by at least two capillary passages of which the ratio of the length L l of the long passage and the length L k of the short passage lies in a range of 3:1 to 15:1 and which are connected to a means for producing a variable pressure differential, and by a detector system with which the flowing of the fluid can be detected.
Claim 3
Dependent Claim 13 words
Apparatus according to claim 1, characterized in that the ratio is about 7:1.
Claim 4
Dependent Claim 19 words
Apparatus according to claim 1, characterized in that the internal diameter of the passages (46,48) is about 15-1000 μm.
Claim 5
Dependent Claim 22 words
Apparatus according to claim 1, characterized in that the passages (46,48) are connected at their entry opening to a main passage (50).
Claim 6
Dependent Claim 20 words
Apparatus according to claim 4, characterized in that the passages (46,48) are connected in U-form to the main passage (50).
Claim 7
Dependent Claim 15 words
Apparatus as in claim 1 wherein said variable pressure means comprises a hydrodynamic pressure generator.
Claim 8
Dependent Claim 26 words
Apparatus according to claim 1, characterized in that the means for producing a variable pressure differential in the passages (46,48) is a pneumatic pressure generator (62).
Claim 9
Dependent Claim 32 words
Apparatus according to claim 1, characterized in that the detector system (22,38) comprises a light source (74), a magnifying optical system (76,78,80), a diaphragm (82) and at least one light detector (84).
Claim 10
Dependent Claim 23 words
Apparatus according to claim 8, characterized in that the detector system (22,38) comprises light sensors corresponding to a plurality of fixed measuring points.
Claim 11
Dependent Claim 114 words
Apparatus for determining the flow shear stress of suspensions, in particular blood, comprising a means having a network of capillary passages, at least two of said capillary passages having a length ratio between the length L l of the long passage and the length L k of the short passage ranging from 3:1 to 15:1, said network of capillary passages being connected to a means for producing a variable pressure differential, and a detector system with which the flowing of the fluid can be detected, wherein said passages are connected at their entry opening to a main passage and wherein the passages are provided in a solid, cast body of a substantially transparent plastic.
Claim 12
Dependent Claim 114 words
Apparatus for determining the flow shear stress of suspensions, in particular blood, comprising a means having a network of capillary passages, at least two of said capillary passages having a length ratio between the length L l of the long passage and the length L k of the short passage ranging from 3:1 to 15:1, said network of capillary passages being connected to a means for producing a variable pressure differential, and a detector system with which the flowing of the fluid can be detected, wherein said passages are connected at their entry opening to a main passage and wherein the passages are provided in a solid, cast body of a substantially transparent plastic.
Claim 13
Dependent Claim 127 words
Apparatus for determining the flow shear stress of suspensions, in particular blood, comprising measuring chamber means having a network of capillary passages, characterized by at least two capillary passages having a length ratio between the length L 1 of the long passage and the length L k of the short passage ranging from 3:1 to 15:1 and which are connected to a means for producing a variable pressure differential, and by a detector system with which the flowing of the fluid can be detected, wherein said passages are connected at their entry opening to a main passage and wherein said measuring chamber means is comprised of a solid body and wherein hollow filaments of a hydrophobic material are provided in said solid body and comprise said passages.
Claim 14
Dependent Claim 127 words
Apparatus for determining the flow shear stress of suspensions, in particular blood, comprising measuring chamber means having a network of capillary passages, characterized by at least two capillary passages having a length ratio between the length L 1 of the long passage and the length L k of the short passage ranging from 3:1 to 15:1 and which are connected to a means for producing a variable pressure differential, and by a detector system with which the flowing of the fluid can be detected, wherein said passages are connected at their entry opening to a main passage and wherein said measuring chamber means is comprised of a solid body and wherein hollow filaments of a hydrophobic material are provided in said solid body and comprise said passages.
Claim 15
Dependent Claim 120 words
Apparatus for determining the flow shear stress of suspensions, in particular blood, comprising a means having a network of capillary passages, characterized by at least two capillary passages of which the ratio of the length L 1 of the long passage and the length L k of the short passage lies in a range of 3:1 to 15:1 and which are connected to a means for producing a variable pressure differential, and by a detector system with which the flowing of the fluid can be detected and wherein said means having a network of capillary passages further includes a main passage, with said capillary passages and said main passage comprising a measuring chamber which is provided within the detector system.
Claim 16
Dependent Claim 120 words
Apparatus for determining the flow shear stress of suspensions, in particular blood, comprising a means having a network of capillary passages, characterized by at least two capillary passages of which the ratio of the length L 1 of the long passage and the length L k of the short passage lies in a range of 3:1 to 15:1 and which are connected to a means for producing a variable pressure differential, and by a detector system with which the flowing of the fluid can be detected and wherein said means having a network of capillary passages further includes a main passage, with said capillary passages and said main passage comprising a measuring chamber which is provided within the detector system.
Claim 17
Dependent Claim 109 words
Apparatus for determining the flow shear stress of suspensions, in particular blood, comprising a means having a network of capillary passages, characterized by at least two capillary passages of which the ratio of the length L 1 of the long passage and the length L k of the short passage lies in a range of 3:1 to 15:1 and which are connected to a means for producing a variable pressure differential, and by a detector system with which the flowing of the fluid can be detected wherein at least one of the said capillary passages includes electrodes for determining the conductivity of the suspension disposed in that respective passage.
Claim 18
Dependent Claim 109 words
Apparatus for determining the flow shear stress of suspensions, in particular blood, comprising a means having a network of capillary passages, characterized by at least two capillary passages of which the ratio of the length L 1 of the long passage and the length L k of the short passage lies in a range of 3:1 to 15:1 and which are connected to a means for producing a variable pressure differential, and by a detector system with which the flowing of the fluid can be detected wherein at least one of the said capillary passages includes electrodes for determining the conductivity of the suspension disposed in that respective passage.
Claim 19
Dependent Claim 96 words
Apparatus for determining the flow shear stress of suspensions, in particular blood, including a measuring chamber formed from a substantially transparent material, said chamber including a main passage, at least a first capillary passage for the suspension material connected to a pressure generator by way of said main passage, said apparatus further including a movable optical detector system for observing the supension material in said at least first capillary passage, at least a second capillary passage, said at least first and second capillary passages being comprised of different lengths and arranged rectangularly to said main passage.
Claim 20
Dependent Claim 96 words
Apparatus for determining the flow shear stress of suspensions, in particular blood, including a measuring chamber formed from a substantially transparent material, said chamber including a main passage, at least a first capillary passage for the suspension material connected to a pressure generator by way of said main passage, said apparatus further including a movable optical detector system for observing the supension material in said at least first capillary passage, at least a second capillary passage, said at least first and second capillary passages being comprised of different lengths and arranged rectangularly to said main passage.
Claim 21
Dependent Claim 40 words
Apparatus according to claim 14, wherein the ratio of the length L 1 of the longer of said capillary passages and the length L k of the shorter of said capillary passages lies in a range of 3:1 to 15:1.

References Cited (Backward Citations)

US3559464A Cited
US3908442A Cited
US4143541A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1988-05-27 1988-11-26 1989-05-28 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1992-05-27 1992-11-26 1993-05-28 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1996-05-27 1996-11-26 1997-05-28 $7700.00 Window Closed / Lapsed

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