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US4517987A Expired / Lapsed US ⏱️ 0.0 years remaining

Method for measurement of nonradioisotopic aerosol retained in the lungs with re-breathing

Assignee: Individual
•
Filing: 1982-04-02
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Granted: 1985-05-21
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Expires: 2002-04-02
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Abstract

Abstract A subject rebreathes an inert aerosol from a closed system and, during each of a plurality of breaths, the aerosol concentration in the closed system is determined and compared to determine differences with a predetermined concentration value. Identified differences indicating enhanced aerosol deposition signify airway narrowing and/or an increase in accumulated airway secretions.

Inventors

  • 👤 Marvin A. Sackner
  • 👤 Chong S. Kim

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-08 01:11
CPC Classifications
A; A61; A61B; A61B5/00; A61B5/08; A61B5/085; A61B5/087

Claims Analysis

Total Claims: 6
Claim 1
Independent Claim 84 words
A method for determining a subject's airway function as affected by airway cross-sectional dimensions and/or retention of tracheobroncheal secretions, comprising: said subject re-breathing an inert aerosol from a closed system; determining the aerosol concentration in said closed system during each of a plurality of breaths; comparing said aerosol concentration determination after each of said plurality of breaths with a predetermined aerosol concentration value to identify differences therebetween, wherein identified differences indicating enhanced aerosol deposition signify airway narrowing and/or an increase in accumulated airway secretions.
Claim 2
Independent Claim 84 words
A method for determining a subject's airway function as affected by airway cross-sectional dimensions and/or retention of tracheobroncheal secretions, comprising: said subject re-breathing an inert aerosol from a closed system; determining the aerosol concentration in said closed system during each of a plurality of breaths; comparing said aerosol concentration determination after each of said plurality of breaths with a predetermined aerosol concentration value to identify differences therebetween, wherein identified differences indicating enhanced aerosol deposition signify airway narrowing and/or an increase in accumulated airway secretions.
Claim 3
Dependent Claim 20 words
A method in accordance with claim 1 wherein said predetermined aerosol concentration value comprises a predicted value for said subject.
Claim 4
Dependent Claim 43 words
A method in accordance with claim 1 wherein said predetermined aerosol concentration value comprises a measurement obtained from said subject for a corresponding one of a plurality of breaths during a prior determination of the subject's airway function in accordance with said method.
Claim 5
Dependent Claim 72 words
A method in accordance with claim 3, further comprising measuring the cross-sectional dimensions of the subject's airway, and comparing said measured airway cross-sectional dimensions with the airway cross-sectional dimensions measured for said subject during said prior determination of the subject's airway function in accordance with said method, whereby identified differences indicating enhanced airway deposition accompanied by no substantial change in said measured airway cross-sectional dimensions signify an increase in accumulated airway secretions.
Claim 6
Dependent Claim 56 words
A method in accordance with claim 1 wherein said subject re-breathing and said determining of aerosol concentration is continued for a plurality of breaths until the aerosol concentration is determined to be no greater than approximately ten percent of the aerosol concentration in said closed system prior to the subject's first breath of the inert aerosol.

References Cited (Backward Citations)

US3527205A Cited
US3785370A Cited
US4180734A Cited
US4307730A Cited
US4370986A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1988-05-20 1988-11-19 1989-05-21 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1992-05-20 1992-11-19 1993-05-21 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1996-05-20 1996-11-19 1997-05-21 $7700.00 Window Closed / Lapsed

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