US4515814A
Expired / Lapsed
US
⏱️ 0.0 years remaining
3-Phenoxypropan-2-ol derivatives for treating glaucoma
Assignee: Synthelabo SA
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Filing: 1982-08-30
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Granted: 1985-05-07
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Expires: 2002-08-30
Abstract
Abstract New 3-phenoxypropan-2-ol derivatives of the formula: ##STR1## wherein R represents a cycloalkyl radical having 5 or 6 carbon atoms, X represents an oxygen atom or a bond, and R' represents the isopropyl or tert.-butyl radical, have been found to be useful in therapy, and more particularly in the treatment of cardiovascular diseases and glaucoma.
Inventors
- 👤 Alexander E. Wick
- 👤 Jean Binet
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 05:59
CPC Classifications
C; C07; C07D; C07D303/00; C07D303/02; C07D303/12; C07D303/18; C07D303/20; C07D303/24; A; A61; A61P; A61P27/00; A61P27/02; A61P27/06; A61P9/00; C07C; C07C309/00; C07C43/00; C07C43/02; C07C43/18; C07C43/196; C07C43/20; C07C43/215; C07C43/23; C07C45/00; C07C45/61; C07C45/67; C07C45/673; C07C45/68; C07C45/70; C07C45/71
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
75 words
A method for the treatment of a patient with glaucoma which comprises administering to such patient a 3-phenoxypropan-2-ol derivative, in the form of a racemate or an enantiomer, of the formula: ##STR28## wherein R is a cycloalkyl radical having 5 or 6 carbon atoms, X is an oxygen atom or a bond, and R' is isopropyl or tert.-butyl or a pharmaceutically acceptable acid addition salt thereof, in an amount effective to alleviate the glaucoma condition.
Claim 2
Independent Claim
75 words
A method for the treatment of a patient with glaucoma which comprises administering to such patient a 3-phenoxypropan-2-ol derivative, in the form of a racemate or an enantiomer, of the formula: ##STR28## wherein R is a cycloalkyl radical having 5 or 6 carbon atoms, X is an oxygen atom or a bond, and R' is isopropyl or tert.-butyl or a pharmaceutically acceptable acid addition salt thereof, in an amount effective to alleviate the glaucoma condition.
Claim 3
Dependent Claim
10 words
The method of claim 1 wherein said derivative is 3-[4-(2-cyclopentyloxyethyl)-phenoxy]-1-isopropylaminopropan-2-ol.
Claim 4
Dependent Claim
14 words
The method of claim 1 wherein said derivative is the (S)(-) isomer of 3-[4-(2-cyclopentyloxyethyl)-phenoxy]-1-isopropylaminopropan-2-ol.
Claim 5
Dependent Claim
10 words
The method of claim 1 wherein said derivative is 3-[4-(2-cyclopentyloxyethoxy)-phenoxy]-1-isopropylamino-propan-2-ol.
Claim 6
Dependent Claim
10 words
The method of claim 1 wherein said derivative is 3-[4-(2-cyclohexyloxyethyl)-phenoxy]-1-isopropylamino-propan-2-ol.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1988-05-06 | 1988-11-05 | 1989-05-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1992-05-06 | 1992-11-05 | 1993-05-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1996-05-06 | 1996-11-05 | 1997-05-07 | $7700.00 | Window Closed / Lapsed |