US4513002A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Cycloheptene derivatives
Assignee: F Hoffmann La Roche AG
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Filing: 1981-12-14
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Granted: 1985-04-23
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Expires: 2001-12-14
Abstract
Abstract 1-[2-(4,5,10,11-Tetrahydro-1H-dibenzo[a,d]cyclohepten-5-yl)ethyl]pyrro lidine of the formula <IMAGE> I and its pharmaceutically acceptable acid addition salts, prepared through various intermediates, are described. The compounds have valuable histamine-H1 antagonistic properties and are suitable for the control or prevention of allergic reactions, such as, urticaria, hay fever, anaphylaxis and over-sensitivity to medicaments.
Inventors
- 👤 Werner Aschwanden
- 👤 Quirico Branca
- 👤 Emilio Kyburz
- 👤 Rudolf Pfister
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 22:37
CPC Classifications
C; C07; C07D; C07D207/00; C07D207/02; C07D207/04; C07D295/00; C07D295/02; C07D295/027; C07D295/03; A; A61; A61P; A61P37/00; A61P37/08; C07C; C07C2603/00; C07C2603/02; C07C2603/04; C07C2603/30; C07C2603/32
Claims Analysis
Total Claims: 3
Claim 1
Independent Claim
30 words
A method of controlling or preventing allergic reactions which comprises administering to a host requiring such treatment an effective amount of 1-[2-(4,5,10,11-tetrahydro-1H-dibenzo[a,d]cyclohepten-5-yl)ethyl]pyrrolidine or a pharmaceutically acceptable acid addition salt thereof.
Claim 2
Independent Claim
30 words
A method of controlling or preventing allergic reactions which comprises administering to a host requiring such treatment an effective amount of 1-[2-(4,5,10,11-tetrahydro-1H-dibenzo[a,d]cyclohepten-5-yl)ethyl]pyrrolidine or a pharmaceutically acceptable acid addition salt thereof.
Claim 3
Dependent Claim
31 words
A method in accordance with claim 1, wherein 1-[2-(4,5,10,11-tetrahydro-1H-dibenzo[a,d]cyclohepten-5-yl)ethyl]pyrrolidine or a pharmaceutically acceptable acid addition salt thereof is administered orally in a daily dosage of about 10 mg to 150 mg.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1988-04-22 | 1988-10-22 | 1989-04-23 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1992-04-22 | 1992-10-22 | 1993-04-23 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1996-04-22 | 1996-10-22 | 1997-04-23 | $7700.00 | Window Closed / Lapsed |