Patent US4508712A successfully refreshed from Google Patents.
US4508712A
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US
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Atrial peptide
Assignee: Washington University in St. Louis
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Filing: 1984-05-04
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Granted: 1985-04-02
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Expires: 2004-05-04
Abstract
Abstract A novel atrial peptide having useful natriuretic, diuretic and vasodilating activity is disclosed with the following amino acid sequence: <IMAGE> <IMAGE> <IMAGE> <IMAGE> <IMAGE> <IMAGE> <IMAGE> <IMAGE> <IMAGE> <IMAGE> <IMAGE> +TR <IMAGE>
Inventors
- 👤 Philip Needleman
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-05 14:19
CPC Classifications
C; C07; C07K; C07K14/00; C07K14/435; C07K14/575; C07K14/58; A; A61; A61P; A61P7/00; A61P7/10; A61K; A61K38/00
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
16 words
A peptide having potent natriuretic, diruetic and vasodilating activity comprising the following amino acid sequence: ##STR4##
Claim 2
Dependent Claim
16 words
A peptide having potent natriuretic, diruetic and vasodilating activity comprising the following amino acid sequence: ##STR4##
Claim 3
Dependent Claim
26 words
A therapeutic composition of matter for producing natriuresis, diuresis, or vasodilation comprising a therapeutically effective amount of the peptide of claim 1 and pharmaceutically acceptable carrier.
Claim 4
Dependent Claim
26 words
A method for producing natriuresis, diuresis or vasodilation in a mammal comprising administering to said mammal a therapeutically effective amount of the peptide of claim 1.
Claim 5
Dependent Claim
18 words
A peptide fragment comprising the sequence of amino acids 19 to 111 of the peptide of claim 1.
Claim 6
Dependent Claim
26 words
A therapeutic composition of matter for producing natriuresis, diuresis or vasodilation comprising a therapeutically effective amount of the peptide of claim 4 and pharmaceutically acceptable carrier.
Claim 7
Dependent Claim
26 words
A method for producing natriuresis, diuresis or vasodilation in a mammal comprising administering to said mammal a therapeutically effective amount of the peptide of claim 4.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1988-04-01 | 1988-10-01 | 1989-04-02 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1992-04-01 | 1992-10-01 | 1993-04-02 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1996-04-01 | 1996-10-01 | 1997-04-02 | $7700.00 | Window Closed / Lapsed |