US4507319A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Skin treatment composition
Assignee: Lever Brothers Co
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Filing: 1983-01-31
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Granted: 1985-03-26
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Expires: 2003-01-31
Abstract
Abstract A cosmetically acceptable composition for topical application to human skin comprises from 0.1 to 20% by weight of a substituted 2-hydroxyoctanoic acid or 2-ketooctanoic acid or a mixture thereof, together with an amount of a special neutralizing agent sufficient to adjust the pH of the composition to a value of from 3 to 7. The special neutralizing agent is one having a cation whose ionic radius is at least 100 pm.
Inventors
- 👤 Martin D. Barratt
- 👤 Paul A. Bowser
- 👤 James A. Durrant
- 👤 Dieno George
- 👤 Keith J. Hall
- 👤 John C. Hill
- 👤 Michael R. Lowry
- 👤 Colin Prottey
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 16:19
CPC Classifications
A; A61; A61Q; A61Q19/00; A61Q19/007; A61K; A61K8/00; A61K8/18; A61K8/30; A61K8/33; A61K8/36; A61K8/365
Claims Analysis
Total Claims: 21
Claim 1
Independent Claim
56 words
A cosmetically acceptable aqueous composition for topical application to human skin, which comprises: (i) from 0.1 to 20% by weight of 2-hydroxyoctanoic acid; (ii) from 0.1 to 50% by weight of ethyl lactate; and (iii) an amount of an alkanolamine sufficient to adjust the pH of the composition to a value of from 3.8 to 4.5.
Claim 2
Dependent Claim
56 words
A cosmetically acceptable aqueous composition for topical application to human skin, which comprises: (i) from 0.1 to 20% by weight of 2-hydroxyoctanoic acid; (ii) from 0.1 to 50% by weight of ethyl lactate; and (iii) an amount of an alkanolamine sufficient to adjust the pH of the composition to a value of from 3.8 to 4.5.
Claim 3
Dependent Claim
67 words
A cosmetically acceptable aqueous composition for topical application to human skin, which comprises: (i) from 0.1 to 20% by weight of 2-hydroxyoctanoic acid; (ii) from 0.1 to 20% by weight of 2-hydroxypropionic acid; (iii) from 0.1 to 50% by weight of ethyl lactate; and (iv) and an amount of an alkanolamine sufficient to adjust the pH of the composition to a value of from 3.8 to 4.5.
Claim 4
Dependent Claim
67 words
A cosmetically acceptable aqueous composition for topical application to human skin, which comprises: (i) from 0.1 to 20% by weight of 2-hydroxyoctanoic acid; (ii) from 0.1 to 20% by weight of 2-hydroxypropionic acid; (iii) from 0.1 to 50% by weight of ethyl lactate; and (iv) and an amount of an alkanolamine sufficient to adjust the pH of the composition to a value of from 3.8 to 4.5.
Claim 5
Dependent Claim
108 words
A cosmetically acceptable aqueous composition for topical application to human skin, which composition comprises: (i) from 0.1 to 20% by weight of a substituted octanoic acid chosen from 2-hydroxyoctanoic acid, 2-ketooctanoic acid or a mixture thereof; (ii) an amount of neutralising agent sufficient to adjust the pH of the composition to a value of from 3 to 7, the neutralising agent having a cation whose ionic radius is at least 100 pm; and (iii) from 0.1 to 50% by weight of a C 2 to C 4 alkyl lactate selected from the group consisting of ethyl lactate, n-propyl lactate, iso-propyl lactate, n-butyl lactate, iso-butyl lactate and mixtures thereof.
Claim 6
Dependent Claim
108 words
A cosmetically acceptable aqueous composition for topical application to human skin, which composition comprises: (i) from 0.1 to 20% by weight of a substituted octanoic acid chosen from 2-hydroxyoctanoic acid, 2-ketooctanoic acid or a mixture thereof; (ii) an amount of neutralising agent sufficient to adjust the pH of the composition to a value of from 3 to 7, the neutralising agent having a cation whose ionic radius is at least 100 pm; and (iii) from 0.1 to 50% by weight of a C 2 to C 4 alkyl lactate selected from the group consisting of ethyl lactate, n-propyl lactate, iso-propyl lactate, n-butyl lactate, iso-butyl lactate and mixtures thereof.
Claim 7
Dependent Claim
23 words
The composition according to claim 3, wherein the neutralising agent is one having a cation whose ionic radius is at least 200 pm.
Claim 8
Dependent Claim
25 words
The composition according to claim 3, wherein the neutralising agent is an alkanolamine selected from the group consisting of monoalkanolamines, dialkanolamines, trialkanolamines and mixtures thereof.
Claim 9
Dependent Claim
16 words
The composition according to claim 3, which comprises from 5 to 95% by weight of water.
Claim 10
Dependent Claim
33 words
The composition according to claim 3, further comprising a plasticisation potentiating amount of a plasticisation potentiator which is capable of increasing the cloud point temperature of polyoxyethylene(8)nonylphenyl ether by at least 2° C.
Claim 11
Dependent Claim
28 words
The composition according to claim 7, wherein the plasticisation potentiator is selected from the group consisting of methanol, ethanol, propane-1-ol, propane-1,2-diol, butane-1,4-diol, dipropane-1,2-diol, N-methyl-2-pyrrolidone, 2-pyrrolidone and mixtures thereof.
Claim 12
Independent Claim
83 words
A method for the treatment of acne which comprises applying topically to acneic skin an effective amount of a cosmetically acceptable aqueous composition comprising: (i) from 0.1 to 20% by weight of a substituted octanoic acid chosen from 2-hydroxyoctanoic acid, 2-ketooctanoic acid or a mixture thereof; and (ii) an amount of neutralising agent sufficient to adjust the pH of the composition to a value of from 3 to 7, the neutralising agent having a cation whose ionic radius is at least 100 pm.
Claim 13
Independent Claim
83 words
A method for the treatment of acne which comprises applying topically to acneic skin an effective amount of a cosmetically acceptable aqueous composition comprising: (i) from 0.1 to 20% by weight of a substituted octanoic acid chosen from 2-hydroxyoctanoic acid, 2-ketooctanoic acid or a mixture thereof; and (ii) an amount of neutralising agent sufficient to adjust the pH of the composition to a value of from 3 to 7, the neutralising agent having a cation whose ionic radius is at least 100 pm.
Claim 14
Dependent Claim
26 words
A method according to claim 9, wherein the neutralising agent of the composition is one having a cation whose ionic radius is at least 200 pm.
Claim 15
Dependent Claim
28 words
The method according to claim 9, wherein the neutralising agent of the composition is an alkanolamine selected from the group consisting of monoalkanolamines, dialkanolamines, trialkanolamines and mixtures thereof.
Claim 16
Dependent Claim
16 words
A method according to claim 9, which comprises from 5 to 95% by weight of water.
Claim 17
Dependent Claim
46 words
The method according to claim 9, wherein the applied composition further comprises from 0.1 to 50% by weight of a C 2 to C 4 alkyl lactate selected from the group consisting of ethyl lactate, n-propyl lactate, iso-propyl lactate, n-butyl lactate, isobutyl lactate and mixture thereof.
Claim 18
Dependent Claim
46 words
The method according to claim 9, wherein the applied composition further comprises from 0.1 to 20% by weight of a substituted alkanoic acid selected from the group consisting of C 3 to C 6 2-hydroxyalkanoic acids, C 3 to C 6 2-ketoalkanoic acids or mixtures thereof.
Claim 19
Dependent Claim
21 words
The method according to claim 14, wherein the C 3 to C 6 2-hydroxyalkanoic acid of the composition is 2-hydroxypropionic acid.
Claim 20
Dependent Claim
37 words
The method according to claim 9, wherein the applied composition further comprises a plasticisation potentiating amount of a plasticisation potentiator which is capable of increasing the cloud point temperature of polyoxyethylene(8)nonylphenyl ether by at least 2° C.
Claim 21
Dependent Claim
31 words
The method according to claim 16, wherein the plasticisation potentiator of the composition is selected from the group consisting of methanol, ethanol, propane-1-ol, propane-1,2-diol, butane-1,4-diol, dipropane-1,2-diol, N-methyl-2-pyrrolidone, 2-pyrrolidone and mixtures thereof.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1988-03-25 | 1988-09-24 | 1989-03-26 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1992-03-25 | 1992-09-24 | 1993-03-26 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1996-03-25 | 1996-09-24 | 1997-03-26 | $7700.00 | Window Closed / Lapsed |