Patent US4490472A successfully refreshed from Google Patents.
US4490472A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Sensitive tests for malignancies based on DNA detection
Assignee: Imreg Inc
•
Filing: 1982-06-17
•
Granted: 1984-12-25
•
Expires: 2002-06-17
Abstract
Abstract An improved, more convenient, more sensitive test for detection of certain malignancies in human and animal subjects is disclosed. Sera from test subjects is mixed with labeled DNA in the presence of an enzyme-conjugated resin. Sera from normal and cancerous subjects react differently with the resin, permitting a diagnosis of the subject.
Inventors
- 👤 A. Arthur Gottlieb
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 07:47
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/53; G01N33/575; C; C12; C12N; C12N15/00; C12Q; C12Q1/00; C12Q1/68; C12Q1/6876; C12Q1/6883; C12Q1/6886; Y; Y10; Y10S; Y10S436/00; Y10S436/804; Y10S436/811; Y10S436/813; Y10S436/815
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
8 words
Substantially pure DNA-L, substantially free of other DNAs.
Claim 2
Dependent Claim
8 words
Substantially pure DNA-L, substantially free of other DNAs.
Claim 3
Dependent Claim
11 words
The DNA-L of claim 1, wherein said DNA-L is labeled DNA-L.
Claim 4
Dependent Claim
11 words
The DNA-L of claim 1, wherein said DNA-L is cloned DNA-L.
Claim 5
Dependent Claim
11 words
The DNA-L of claim 3 wherein said DNA-L is labeled DNA-L.
Claim 6
Dependent Claim
23 words
The DNA-L of claim 2 wherein said labeled DNA-L is labeled with a member of the group consisting of phosphorous 32 and tritium.
Claim 7
Dependent Claim
10 words
The DNA-L of claim 3 wherein said DNA-L is DNA-1.
Claim 8
Dependent Claim
10 words
The DNA-L of claim 3 wherein said DNA-L is DNA-2.
Claim 9
Dependent Claim
14 words
A substantially pure, labeled mixture of DNA-1 and DNA-2, substantially free of other DNAs.
Claim 10
Dependent Claim
14 words
A substantially pure, labeled mixture of DNA-1 and DNA-2, substantially free of other DNAs.
References Cited (Backward Citations)
US4358535A
Cited
US4358535B1
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-12-25 | 1988-06-25 | 1988-12-25 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-12-25 | 1992-06-25 | 1992-12-25 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-12-25 | 1996-06-25 | 1996-12-25 | $7700.00 | Window Closed / Lapsed |