Patent US4490353A successfully refreshed from Google Patents.
US4490353A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Antiplaque dentifrice with improved fluoride stability
Assignee: Colgate Palmolive Co
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Filing: 1983-07-13
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Granted: 1984-12-25
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Expires: 2003-07-13
Abstract
Abstract A stable antiplaque dentifrice with improved foaming and improved fluoride stability containing an antiplaque quaternary ammonium compound, a betaine surfactant to improve foaming without inactivating the anti-bacterial and antiplaque activity of the quaternary ammonium compound, a humectant selected from the group consisting of polyethylene glycol, sorbitol, and mixtures thereof, a nonionic gelling agent, preferably hydroxyethylcellulose and a fluorine-containing compound capable of providing a fluoride ion, a small amount of glycerin to improve fluoride stability in polyethylene glycol humectant, in an aqueous vehicle containing a dental abrasive. A small amount of glycerin, as low as 1%, improves the long term fluoride stability of the dentifrice without adversely affecting the cosmetic stability thereof.
Inventors
- 👤 Richard J. Crawford
- 👤 Kathleen M. Yuhasz
- 👤 John P. Curtis
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 21:02
CPC Classifications
A; A61; A61Q; A61Q11/00; A61K; A61K8/00; A61K8/18; A61K8/19; A61K8/20; A61K8/21; A61K8/30; A61K8/33; A61K8/34; A61K8/345; A61K8/39; A61K8/40; A61K8/41; A61K8/416; A61K8/44; A61K8/72; A61K8/73; A61K8/731; A61K2800/00; A61K2800/40; A61K2800/54; A61K2800/542; A61K2800/5422
Claims Analysis
Total Claims: 18
Claim 1
Independent Claim
57 words
A stable antiplaque dentifrice with improved foaming and improved fluoride stability, comprising an effective amount of an antiplaque quaternary ammonium compound, at least 1.5% betaine surfactant by weight, a humectant selected from the group consisting of polyethylene glycol, sorbitol and mixtures thereof, a nonionic gelling agent, a fluoride-providing compound, in an aqueous vehicle containing a dental abrasive.
Claim 2
Dependent Claim
57 words
A stable antiplaque dentifrice with improved foaming and improved fluoride stability, comprising an effective amount of an antiplaque quaternary ammonium compound, at least 1.5% betaine surfactant by weight, a humectant selected from the group consisting of polyethylene glycol, sorbitol and mixtures thereof, a nonionic gelling agent, a fluoride-providing compound, in an aqueous vehicle containing a dental abrasive.
Claim 3
Dependent Claim
18 words
The dentifrice according to claim 1, wherein the betaine content constitutes about 1.5-2% by weight of the formulation.
Claim 4
Dependent Claim
19 words
The dentifrice of claim 2, wherein the nonionic gelling agent is hydroxyethylcellulose in amounts of about 0.5-2% by weight.
Claim 5
Dependent Claim
29 words
The dentifrice according to claim 3, containing about 20-30% by weight of polyethylene glycol having an average molecular weight of 600 and 1-10% glycerine by weight as fluoride stabilizer.
Claim 6
Dependent Claim
13 words
The dentifrice according to claim 3, containing about 20-30% by weight of sorbitol.
Claim 7
Dependent Claim
16 words
The dentifrice according to claim 1, containing about 40-60% by weight of a water-insoluble dental abrasive.
Claim 8
Dependent Claim
13 words
The dentifrice according to claim 6, wherein the dental abrasive is dicalcium phosphate.
Claim 9
Dependent Claim
21 words
The dentifrice according to claim 3, wherein the antiplaque agent is benzethonium chloride in an amount of about 0.01-5% by weight.
Claim 10
Dependent Claim
18 words
The dentifrice according to claim 6, wherein the dentifrice is a mixture of calcined alumina and hydrated alumina.
Claim 11
Dependent Claim
17 words
The dentifrice according to claim 1, wherein the fluoride-providing compound constitutes 0.05-2% by weight of the dentifrice.
Claim 12
Dependent Claim
13 words
The dentifrice according to claim 10, wherein the fluoride-providing compound is sodium monofluorophosphate.
Claim 13
Dependent Claim
11 words
The dentifrice of claim 2, wherein the betaine is cocoamidopropyl betaine.
Claim 14
Dependent Claim
14 words
The dentifrice according to claim 1, which is free of nonionic and anionic surfactants.
Claim 15
Dependent Claim
12 words
The dentifrice according to claim 6, wherein the abrasive is dicalcium phosphate.
Claim 16
Dependent Claim
11 words
The dentifrice according to claim 6, wherein the abrasive is alumina.
Claim 17
Dependent Claim
18 words
The dentifrice according to claim 15, wherein the abrasive is a mixture of hydrated alumina and calcined alumina.
Claim 18
Dependent Claim
22 words
The dentifrice according to claim 3, wherein the humectant comprises about 20-30% by weight of a mixture of sorbitol and polyethylene glycol.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-12-25 | 1988-06-25 | 1988-12-25 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-12-25 | 1992-06-25 | 1992-12-25 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-12-25 | 1996-06-25 | 1996-12-25 | $7700.00 | Window Closed / Lapsed |