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Process for producing film

Assignee: Boehringer Ingelheim GmbH
•
Filing: 1983-02-03
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Granted: 1984-12-25
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Expires: 2003-02-03
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Abstract

Abstract A novel process for the preparation of a pharmaceutical preparation in the form of an polyacrylate film for long-term transdermal administration of systemic pharmaceuticals comprising forming a homogeneous solution of an effective amount of a systemically acting pharmaceutical and a freeze-dried latex of a polyacrylate copolymer of methyl and/or ethyl esters of acrylic acid and methacrylic acid formed by emulsion polymerization and having an average molecular weight of about 800,000 in at least one organic solvent, forming a thin layer of the said solution and drying the layer to form a polyacrylate film and the film product produced by the said process.

Inventors

  • 👤 Bernd Zierenberg

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-24 19:25
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/70; A61K9/7023; A61K9/703; A61K9/7038; A61K9/7046; A61K9/7053; A61K9/7061; A61K9/7007; A61L; A61L26/00; A61L26/0061; A61L26/0076

Claims Analysis

Total Claims: 6
Claim 1
Independent Claim 105 words
A process for the preparation of a pharmaceutical composition in the form of a polyacrylate film for long-term transdermal administration of systemic pharmaceuticals, which comprises forming a homogeneous solution of an effective amount of a systemically acting pharmaceutical and a freeze-dried latex of a polyacrylate copolymer having a polymer unit of the formula ##STR1## where R is H or CH 3 and R' is CH 3 or C 2 H 5 formed by emulsion polymerization and having an average molecular weight of about 800,000 in an organic solvent, forming a thin layer of the said solution, and drying the layer to form a polyacrylate film.
Claim 2
Dependent Claim 105 words
A process for the preparation of a pharmaceutical composition in the form of a polyacrylate film for long-term transdermal administration of systemic pharmaceuticals, which comprises forming a homogeneous solution of an effective amount of a systemically acting pharmaceutical and a freeze-dried latex of a polyacrylate copolymer having a polymer unit of the formula ##STR1## where R is H or CH 3 and R' is CH 3 or C 2 H 5 formed by emulsion polymerization and having an average molecular weight of about 800,000 in an organic solvent, forming a thin layer of the said solution, and drying the layer to form a polyacrylate film.
Claim 3
Dependent Claim 11 words
The process of claim 1 wherein the film is prepared continuously.
Claim 4
Dependent Claim 11 words
The process of claim 1 wherein the film is prepared discontinuously.
Claim 5
Dependent Claim 26 words
The process of claim 1 wherein the drying of the film is effected at a temperature from room temperature to the boiling point of the solvent.
Claim 6
Dependent Claim 15 words
The process of claim 1 wherein the polyacrylate contains polyacrylate containing acidic or basic groups.

References Cited (Backward Citations)

US4136145A Cited
DE2920500A1 Cited
CA1136045A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1987-12-25 1988-06-25 1988-12-25 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1991-12-25 1992-06-25 1992-12-25 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1995-12-25 1996-06-25 1996-12-25 $7700.00 Window Closed / Lapsed

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