US4490322A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Process for producing film
Assignee: Boehringer Ingelheim GmbH
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Filing: 1983-02-03
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Granted: 1984-12-25
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Expires: 2003-02-03
Abstract
Abstract A novel process for the preparation of a pharmaceutical preparation in the form of an polyacrylate film for long-term transdermal administration of systemic pharmaceuticals comprising forming a homogeneous solution of an effective amount of a systemically acting pharmaceutical and a freeze-dried latex of a polyacrylate copolymer of methyl and/or ethyl esters of acrylic acid and methacrylic acid formed by emulsion polymerization and having an average molecular weight of about 800,000 in at least one organic solvent, forming a thin layer of the said solution and drying the layer to form a polyacrylate film and the film product produced by the said process.
Inventors
- 👤 Bernd Zierenberg
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 06:58
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/70; A61K9/7023; A61K9/703; A61K9/7038; A61K9/7046; A61K9/7053; A61K9/7061; A61K9/7007; A61L; A61L26/00; A61L26/0061; A61L26/0076
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
105 words
A process for the preparation of a pharmaceutical composition in the form of a polyacrylate film for long-term transdermal administration of systemic pharmaceuticals, which comprises forming a homogeneous solution of an effective amount of a systemically acting pharmaceutical and a freeze-dried latex of a polyacrylate copolymer having a polymer unit of the formula ##STR1## where R is H or CH 3 and R' is CH 3 or C 2 H 5 formed by emulsion polymerization and having an average molecular weight of about 800,000 in an organic solvent, forming a thin layer of the said solution, and drying the layer to form a polyacrylate film.
Claim 2
Dependent Claim
105 words
A process for the preparation of a pharmaceutical composition in the form of a polyacrylate film for long-term transdermal administration of systemic pharmaceuticals, which comprises forming a homogeneous solution of an effective amount of a systemically acting pharmaceutical and a freeze-dried latex of a polyacrylate copolymer having a polymer unit of the formula ##STR1## where R is H or CH 3 and R' is CH 3 or C 2 H 5 formed by emulsion polymerization and having an average molecular weight of about 800,000 in an organic solvent, forming a thin layer of the said solution, and drying the layer to form a polyacrylate film.
Claim 3
Dependent Claim
11 words
The process of claim 1 wherein the film is prepared continuously.
Claim 4
Dependent Claim
11 words
The process of claim 1 wherein the film is prepared discontinuously.
Claim 5
Dependent Claim
26 words
The process of claim 1 wherein the drying of the film is effected at a temperature from room temperature to the boiling point of the solvent.
Claim 6
Dependent Claim
15 words
The process of claim 1 wherein the polyacrylate contains polyacrylate containing acidic or basic groups.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-12-25 | 1988-06-25 | 1988-12-25 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-12-25 | 1992-06-25 | 1992-12-25 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-12-25 | 1996-06-25 | 1996-12-25 | $7700.00 | Window Closed / Lapsed |