US4489058A
Expired / Lapsed
US
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Acne control method
Assignee: Dow Chemical Co
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Filing: 1983-05-23
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Granted: 1984-12-18
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Expires: 2003-05-23
Abstract
Abstract A method for controlling acne or acneform eruptions in humans is disclosed. The method involves the topical application of one or more sebum-imbibing, sebum-retaining polymers either alone or in combination with a pharmaceutically acceptable carrier.
Inventors
- 👤 George E. Lay
- 👤 Daniel H. Haigh
- 👤 Richard A. Knipstein
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 05:08
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/72; A61K8/81; A61K8/8194; A61K31/00; A61K31/74; A61K31/745; A61K31/765; A61K31/78; A61K8/02; A61K8/0241; A61K8/0279; A61K8/8141; A61K8/8152; A61Q; A61Q19/00; A61Q19/008
Claims Analysis
Total Claims: 21
Claim 1
Independent Claim
118 words
A method for controlling acne or acneform eruptions in humans which comprises the topical application of an effective amount of a crosslinked or uncrosslinked sebum-imbibing, sebum-retaining polymer, wherein the polymer is the polymerization product of two or three monomer units selected from the group consisting of styrene or alkylstyrene ring substituted with a straight or branched chain alkyl moiety of from 1 to about 12 carbon atoms; an alkyl ester derived from an alcohol containing from about 8 to about 20 carbon atoms and acrylic or methacrylic acid; a vinyl ester of an aliphatic carboxylic acid containing from about 8 to about 20 carbon atoms; and an aliphatic diolefin of from about 4 to about 6 carbon atoms.
Claim 2
Independent Claim
118 words
A method for controlling acne or acneform eruptions in humans which comprises the topical application of an effective amount of a crosslinked or uncrosslinked sebum-imbibing, sebum-retaining polymer, wherein the polymer is the polymerization product of two or three monomer units selected from the group consisting of styrene or alkylstyrene ring substituted with a straight or branched chain alkyl moiety of from 1 to about 12 carbon atoms; an alkyl ester derived from an alcohol containing from about 8 to about 20 carbon atoms and acrylic or methacrylic acid; a vinyl ester of an aliphatic carboxylic acid containing from about 8 to about 20 carbon atoms; and an aliphatic diolefin of from about 4 to about 6 carbon atoms.
Claim 3
Independent Claim
37 words
A method for controlling acne or acneform eruptions in humans which comprises the topical application of an effective amount of a sebum-imbibing, sebum-retaining homopolymer of an aliphatic diolefin of from about 4 to about 6 carbon atoms.
Claim 4
Independent Claim
37 words
A method for controlling acne or acneform eruptions in humans which comprises the topical application of an effective amount of a sebum-imbibing, sebum-retaining homopolymer of an aliphatic diolefin of from about 4 to about 6 carbon atoms.
Claim 5
Dependent Claim
68 words
The method of claim 1 wherein the polymer is a crosslinked polymer of from about 30 to about 90 percent by weight of styrene and an alkyl ester derived from an alcohol containing from about 8 to about 20 carbon atoms and acrylic or methacrylic acid, crosslinked with from about 0.001 to about 0.1 percent (based on total weight of said polymer) of a polyethylenically unsaturated crosslinking agent.
Claim 6
Dependent Claim
35 words
The method of claim 1 wherein the polymer is a crosslinked polymer of from about 30 to about 90 percent of styrene and an aliphatic diolefin of from about 4 to about 6 carbon atoms.
Claim 7
Dependent Claim
66 words
The method of claim 1 wherein the polymer is a crosslinked polymer of from about 30 to about 90 percent vinyl toluene and an alkyl ester derived from an alcohol containing from about 8 to about 20 carbon atoms and acrylic or methacrylic acid, crosslinked with from about 0.001 to about 0.1 percent (based on total weight of said polymer) of a polyethylenically unsaturated crosslinking agent.
Claim 8
Dependent Claim
56 words
The method of claim 1 wherein the polymer is a crosslinked polymer of alkyl ester monomers derived from an alcohol containing from about 8 to about 20 carbon atoms and acrylic or methacrylic acid, crosslinked with from about 0.001 to about 0.1 percent (based on total weight of said polymer) of a polyethylenically unsaturated crosslinking agent.
Claim 9
Dependent Claim
82 words
The method of claim 1 wherein the polymer is a crosslinked polymer of from about 20 to about 70 percent of a vinyl ester of an aliphatic carboxylic acid containing from about 8 to about 20 carbon atoms and an alkyl ester derived from an alcohol containing from about 8 to about 20 carbon atoms and acrylic or methacrylic acid, cross-linked with from about 0.001 to about 0.1 percent (based on total weight of said polymer) of a polyethylenically unsaturated crosslinking agent.
Claim 10
Dependent Claim
79 words
The method of claim 1 wherein the polymer is a crosslinked polymer of from about 30 to about 90 percent of a tertiary-alkylstyrene containing from about 4 to about 12 carbon atoms and at least one alkyl ester derived from an alcohol containing from about 8 to about 20 carbon atoms and acrylic or methacrylic acid, crosslinked with from about 0.001 to about 0.1 percent (based on the total weight of said polymer) of a polyethylenically unsaturated crosslinking agent.
Claim 11
Dependent Claim
73 words
The method of claim 1 wherein the polymer is a crosslinked polymer of from about 30 to about 90 percent of a tertiary-alkylstyrene containing from about 4 to about 12 carbon atoms and a vinyl ester of an aliphatic carboxylic acid containing from about 8 to about 20 carbon atoms, crosslinked with from about 0.001 to about 0.1 percent (based on the total weight of said polymer) of a polyethylenically unsaturated crosslinking agent.
Claim 12
Dependent Claim
10 words
The method of claim 2 wherein the homopolymer is polybutadiene.
Claim 13
Dependent Claim
18 words
The method of claim 3 wherein the alkyl ester is lauryl methacrylate and the crosslinking agent is divinylbenzene.
Claim 14
Dependent Claim
11 words
The method of claim 4 wherein said aliphatic diolefin is butadiene.
Claim 15
Dependent Claim
18 words
The method of claim 5 wherein said alkyl ester is lauryl methacrylate and the crosslinking agent is divinylbenzene.
Claim 16
Dependent Claim
22 words
The method of claim 6 wherein said alkyl ester monomers are isobornyl methacrylate and lauryl methacrylate and the crosslinking agent is divinylbenzene.
Claim 17
Dependent Claim
27 words
The method of claim 7 wherein the vinyl ester is vinyl stearate, said alkyl ester is isobornyl methacrylate or lauryl methacrylate and the crosslinking agent is divinylbenzene.
Claim 18
Dependent Claim
25 words
The method of claim 8 wherein the tertiary-alkylstyrene is tertiary-butylstyrene, said alkyl ester is lauryl methacrylate or stearyl methacrylate and the crosslinking agent is divinylbenzene.
Claim 19
Dependent Claim
26 words
The method of claim 8 wherein said tertiary-alkylstyrene is tertiary-butylstyrene and is a comonomer with 2-ethylhexyl acrylate and lauryl methacrylate and the crosslinking agent is divinylbenzene.
Claim 20
Dependent Claim
26 words
The method of claim 8 wherein said tertiary-alkylstyrene is tertiary-butylstryene and is a comonomer with 2-ethylhexyl acrylate and stearyl methacrylate and the crosslinking agent is divinylbenzene.
Claim 21
Dependent Claim
22 words
The method of claim 9 wherein the tertiary-alkylstyrene is tertiary-butylstyrene, said vinyl ester is vinyl stearate and the crosslinking agent is divinylbenzene.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-12-18 | 1988-06-18 | 1988-12-18 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-12-18 | 1992-06-18 | 1992-12-18 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-12-18 | 1996-06-18 | 1996-12-18 | $7700.00 | Window Closed / Lapsed |