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US4487782A
Expired / Lapsed
US
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Topical treatment of non-inflammatory acne
Assignee: Ortho Pharmaceutical Corp
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Filing: 1982-03-26
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Granted: 1984-12-11
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Expires: 2002-03-26
Abstract
Abstract Topical treatment of non-inflammatory acne by the administration of 13-cis-retinoic acid is disclosed.
Inventors
- 👤 James A. Mezick
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 19:13
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/30; A61K8/67; A61K8/671; A61K31/00; A61K31/185; A61K31/19; A61K31/20; A61K47/00; A61K47/06; A61K47/08; A61K47/10; A61K9/00; A61K9/0012; A61K9/0014; A61Q; A61Q19/00
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
25 words
The method of treating non-inflammatory acne which comprises applying 13-cis-retinoic acid topically to the affected area in a concentration effective for the treatment of acne.
Claim 2
Independent Claim
25 words
The method of treating non-inflammatory acne which comprises applying 13-cis-retinoic acid topically to the affected area in a concentration effective for the treatment of acne.
Claim 3
Dependent Claim
24 words
The method of claim 1 wherein the 13-cis-retinoic acid is applied in a carrier and the application is continued until the acne has subsided.
Claim 4
Dependent Claim
28 words
The method of claim 1 wherein the 13-cis retinoic acid is applied in a concentration from about 0.01 to 0.5 percent, by weight, of the topically applied composition.
Claim 5
Dependent Claim
24 words
The method of claim 3 wherein the concentration of 13-cis-retinoic acid in the composition is in the order of about 0.1 percent, by weight.
Claim 6
Dependent Claim
13 words
The method of claim 2 wherein the carrier is a water-miscible organic liquid.
Claim 7
Dependent Claim
28 words
The method of claim 5 wherein the carrier consists of a mixture of from about 10-90% by weight of an alcohol and 90-10% by weight of a glycol.
Claim 8
Dependent Claim
17 words
The method of claim 6 wherein the alcohol is ethyl alcohol and the glycol is propylene glycol.
Claim 9
Dependent Claim
17 words
The method of claim 7 wherein the carrier consists of 70% ethyl alcohol and 30% propylene glycol.
References Cited (Backward Citations)
GB1335867A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-12-11 | 1988-06-11 | 1988-12-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-12-11 | 1992-06-11 | 1992-12-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-12-11 | 1996-06-11 | 1996-12-11 | $7700.00 | Window Closed / Lapsed |