§
Luxuse
Patent Intelligence
Sign In
← Back to Patent Explorer
US4482542A Expired / Lapsed US ⏱️ 0.0 years remaining

Antacid material based on magnesium aluminium hydroxide and the preparation thereof

Assignee: Warner Lambert Co LLC
•
Filing: 1983-07-12
•
Granted: 1984-11-13
•
Expires: 2003-07-12
📄 Original PDF 🌐 Google Patents 🔄 Sync Now

Abstract

Abstract The present invention provides a process for the preparation of an antacid material based upon magnesium aluminium hydroxide, wherein magnesium hydroxide and/or magnesium oxide is reacted in an atomic ratio of magnesium to aluminium of 1:1 to 3:1 with an aqueous solution of aluminium sulphate until the pH of the reaction mixture is from 4.0 to 8.0, whereafter water-soluble components are removed from the mixture in known manner and this is isolated and, if desired, dried. The present invention also provides pharmaceutical compositions containing an antacid material prepared by this process, in admixture with a conventional pharmaceutical adjuvant. Furthermore, the present invention provides a method of combating hyperacidity and gastrointestinal diseases, which comprises administering an antacid material prepared by the above process.

Inventors

  • 👤 Michael Schneider
  • 👤 Adolf Knecht

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-01 22:45
CPC Classifications
C; C01; C01F; C01F7/00; C01F7/02; C01F7/34; A; A61; A61K; A61K33/00; A61K33/06; A61K33/08; A61P; A61P1/00; A61P1/04

Claims Analysis

Total Claims: 10
Claim 1
Independent Claim 82 words
A process for the preparation of an antacid material based upon magnesium aluminum hydroxide, substantially free of sodium and carbonate ions, which comprises reacting a magnesium compound selected from the group of magnesium hydroxide, magnesium oxide, or mixtures thereof in an atomic ratio of magnesium to aluminum of 1:1 to 3:1 with an aqueous solution of aluminum sulphate until the pH of the reaction mixtures is from 4.0 to 8.01, then removing water-soluble components from the mixture and, isolating said antacid material.
Claim 2
Dependent Claim 82 words
A process for the preparation of an antacid material based upon magnesium aluminum hydroxide, substantially free of sodium and carbonate ions, which comprises reacting a magnesium compound selected from the group of magnesium hydroxide, magnesium oxide, or mixtures thereof in an atomic ratio of magnesium to aluminum of 1:1 to 3:1 with an aqueous solution of aluminum sulphate until the pH of the reaction mixtures is from 4.0 to 8.01, then removing water-soluble components from the mixture and, isolating said antacid material.
Claim 3
Dependent Claim 24 words
A process according to claim 1, wherein the starting materials are used in an atomic ratio of magnesium to aluminium of 1.3:1 to 2:1.
Claim 4
Dependent Claim 23 words
A process according to claim 1 wherein the reaction is terminated when the pH of the reaction mixture is from 5.0 to 7.0.
Claim 5
Dependent Claim 21 words
A process according to claim 1 wherein the reaction is carried out at a temperature which does not exceed 60° C.
Claim 6
Dependent Claim 23 words
A process according to claim 2 wherein the reaction is terminated when the pH of the reaction mixture is from 5.0 to 7.0.
Claim 7
Dependent Claim 21 words
A process according to claim 5 wherein the reaction is carried out at a temperature which does not exceed 60° C.
Claim 8
Dependent Claim 21 words
A process according to claim 2 wherein the reaction is carried out at a temperature which does not exceed 60° C.
Claim 9
Dependent Claim 21 words
A process according to claim 3 wherein the reaction is carried out at a temperature which does not exceed 60° C.
Claim 10
Dependent Claim 24 words
The process of claim 1 which further comprises drying said antacid material and wherein said antacid material is free of sodium and carbonate ions.

References Cited (Backward Citations)

US3857938A Cited
US4105579A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1987-11-13 1988-05-14 1988-11-13 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1991-11-13 1992-05-14 1992-11-13 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1995-11-13 1996-05-14 1996-11-13 $7700.00 Window Closed / Lapsed

Assigned Categories & Tags

No categories assigned to this patent yet.

Assign Category Tag