US4482474A
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Phospholipid solutions
Assignee: A Natterman und Cie GmbH
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Filing: 1983-05-11
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Granted: 1984-11-13
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Expires: 2003-05-11
Abstract
Abstract Aqueous phospholipid solutions and their preparations, consisting of phospholipids and a solution promoter of the general formula CH 3 (CH 2 ) n CONHCH 2 CH 2 OH, in which n is 3, 4 or 5.
Inventors
- 👤 Juergen Biedermann
- 👤 Hans Betzing
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-03 03:28
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/66; A61K31/683; A61K31/685; A61K47/00; A61K47/06; A61K47/16; A61K47/18; A61K47/24; Y; Y10; Y10S; Y10S516/00; Y10S516/01; Y10S516/07
Claims Analysis
Total Claims: 20
Claim 1
Independent Claim
29 words
Aqueous phospholipid solution comprising as solution promoter a hydroxyethyl amide of the general Formula I CH.sub.3 (CH.sub.2).sub.n CONH--CH.sub.2 --CH.sub.2 --OH I in which n is 3, 4 or 5.
Claim 2
Dependent Claim
29 words
Aqueous phospholipid solution comprising as solution promoter a hydroxyethyl amide of the general Formula I CH.sub.3 (CH.sub.2).sub.n CONH--CH.sub.2 --CH.sub.2 --OH I in which n is 3, 4 or 5.
Claim 3
Dependent Claim
15 words
Aqueous phospholipid solution according to claim 1, wherein the solution contains phosphatidylcholine as the phospholipid.
Claim 4
Dependent Claim
25 words
Aqueous phospholipid solution according to claim 1, wherein the solution contains 1-25 parts phospholipid and 0.75-37.5 parts of a hydroxyethyl amide of the Formula I.
Claim 5
Dependent Claim
15 words
Aqueous phospholipid solution according to claim 3, wherein the solution contains phosphatidylcholine as the phospholipid.
Claim 6
Dependent Claim
18 words
Aqueous phospholipid solution according to claim 1, wherein the solution contains N-(2-Hydroxyethyl)-valeric acid amide as the hydroxyethyl amide.
Claim 7
Dependent Claim
15 words
Aqueous phospholipid solution according to claim 5, wherein the solution contains phosphatidylcholine as the phospholipid.
Claim 8
Dependent Claim
18 words
Aqueous phospholipid solution according to claim 1, wherein the solution contains N-(2-Hydroxyethyl)-caproic acid amide as the hydroxyethyl amide.
Claim 9
Dependent Claim
15 words
Aqueous phospholipid solution according to claim 7, wherein the solution contains phosphatidylcholine as the phospholipid.
Claim 10
Dependent Claim
18 words
Aqueous phospholipid solution according to claim 1, wherein the solution contains N-(2-Hydroxyethyl)-heptanoic acid amide as the hydroxyethyl amide.
Claim 11
Dependent Claim
15 words
Aqueous phospholipid solution according to claim 9, wherein the solution contains phosphatidylcholine as the phospholipid.
Claim 12
Dependent Claim
48 words
Process for the preparation of an aqueous phospholipid solution containing 1 to 25 parts of a phospholipid comprising dissolving the phospholipid in water in the presence of a solution promotor of the general Formula I CH.sub.3 (CH.sub.2).sub.n CONHCH.sub.2 CH.sub.2 OH in which n is 3, 4 or 5.
Claim 13
Dependent Claim
48 words
Process for the preparation of an aqueous phospholipid solution containing 1 to 25 parts of a phospholipid comprising dissolving the phospholipid in water in the presence of a solution promotor of the general Formula I CH.sub.3 (CH.sub.2).sub.n CONHCH.sub.2 CH.sub.2 OH in which n is 3, 4 or 5.
Claim 14
Dependent Claim
29 words
Process according to claim 11, wherein the solution promoter is N-(2-hydroxyethyl)-valeric acid amide, and at least 1.5 parts of the solution promoter are added per each part of phospholipid.
Claim 15
Dependent Claim
13 words
Process according to claim 12, wherein the solution contains phosphatidylcholine as a phospholipid.
Claim 16
Dependent Claim
30 words
Process according to claim 11, wherein the solution promoter is N-(2-hydroxyethyl)-caproic acid amide, and at least 1.2 parts of the solution promoter is added per each part of the phospholipid.
Claim 17
Dependent Claim
13 words
Process according to claim 14, wherein the solution contains phosphatidylcholine as a phospholipid.
Claim 18
Dependent Claim
30 words
Process according to claim 11, wherein the solution promotor is N-(2-hydroxyethyl)-heptanoic acid amide, and at least 0.75 parts of the solution promoter is added per each part of the phospholipid.
Claim 19
Dependent Claim
13 words
Process according to claim 16, wherein the solution contains phosphatidylcholine as a phospholipid.
Claim 20
Dependent Claim
13 words
Process according to claim 11, wherein the solution contains phosphatidylcholine as a phospholipid.
References Cited (Backward Citations)
US3966918A
Cited
US4140759A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-11-13 | 1988-05-14 | 1988-11-13 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-11-13 | 1992-05-14 | 1992-11-13 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-11-13 | 1996-05-14 | 1996-11-13 | $7700.00 | Window Closed / Lapsed |