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US4466740A Expired / Lapsed US ⏱️ 0.0 years remaining

Particle agglutination analyzing plate

Assignee: Olympus Corp
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Filing: 1981-10-07
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Granted: 1984-08-21
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Expires: 2001-10-07
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Abstract

Abstract A plate for use in an immunological analysis on the basis of agglutination reaction of particles, has formed therein a number of reaction vessels each having a conical bottom surface. The plate is formed by molding of chemically resistive acrylic resins. Each vessel has an inclined bottom surface and a plurality of concentric protrusions or depressions are formed in the bottom surface to allow formation of a stable basic layer of settled particles, which basic layer can assure the formation of clear and precise particle patterns on the bottom surface.

Inventors

  • 👤 Tokio Kano
  • 👤 Akira Tamagawa

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-26 14:15
CPC Classifications
G; G01; G01N; G01N1/00; G01N1/02; G01N1/10; B; B01; B01L; B01L3/00; B01L3/50; B01L3/508; B01L3/5085; G01N33/00; G01N33/48; G01N33/50; G01N33/53; G01N33/5302; G01N33/5304

Claims Analysis

Total Claims: 16
Claim 1
Independent Claim 67 words
A particle agglutination analyzing plate, comprising: a plurality of reaction vessels, each having an inclined bottom surface, formed in said plate; a plurality of steps formed in the bottom surface of each of said reaction vessels, said steps having a dimension measured perpendicularly to the inclined bottom surface of 2 to 5 μm and a pitch measured in the inclined bottom surface of 5 to 200 μm.
Claim 2
Dependent Claim 67 words
A particle agglutination analyzing plate, comprising: a plurality of reaction vessels, each having an inclined bottom surface, formed in said plate; a plurality of steps formed in the bottom surface of each of said reaction vessels, said steps having a dimension measured perpendicularly to the inclined bottom surface of 2 to 5 μm and a pitch measured in the inclined bottom surface of 5 to 200 μm.
Claim 3
Dependent Claim 42 words
The particle agglutination analyzing plate according to claim 1, wherein said plurality of steps are formed by a plurality of depressions each having a depth of 2 to 50 μm and a width in the inclined direction of 5 to 200 μm.
Claim 4
Dependent Claim 18 words
The particle agglutination analyzing plate according to claim 2, wherein said plurality of depressions are of sawtooth shape.
Claim 5
Dependent Claim 48 words
The particle agglutination analyzing plate according to claim 1, wherein said plurality of steps are formed by a plurality of protrusions each having a height of 2 to 50 μm and spaced apart from each other in the inclined direction by a distance of 5 to 200 μm.
Claim 6
Dependent Claim 42 words
The particle agglutination analyzing plate according to claim 1, wherein said bottom surface has a periphery and a lowest portion, wherein the depths and widths of the steps are gradually decreased from the periphery to the lowest portion of the bottom surface.
Claim 7
Dependent Claim 42 words
The particle agglutination analyzing plate according to claim 1, wherein said bottom surface has a periphery and a lowest portion, wherein the depths and widths of the steps are gradually increased from the periphery to the lowest portion of the bottom surface.
Claim 8
Dependent Claim 50 words
The particle agglutination analyzing plate according to claim 1, wherein said bottom surface has a periphery and a lowest portion, wherein angles between a horizontal plane and lines connecting successive tops of successively adjacent steps are gradually decreased from the lowest portion to the periphery of the inclined bottom surface.
Claim 9
Dependent Claim 26 words
The particle agglutination analyzing plate according to claim 7, wherein said angles near the lowest portion and the periphery are set at 25°-45° and 15°-30°, respectively.
Claim 10
Dependent Claim 20 words
The particle agglutination analyzing plate according to claim 1, wherein said plate is formed of a molded, chemically resistive material.
Claim 11
Dependent Claim 22 words
The particle agglutination analyzing plate according to claim 1, wherein the plate comprises a plurality of vessels having different shapes and/or dimensions.
Claim 12
Dependent Claim 51 words
A plate according to claim 1, wherein said bottom surface has the shape of an inverted cone, and said plurality of steps are formed substantially from the lowest point of the inverted cone to the outer periphery of the inverted cone, and are arranged regularly and concentrically about the lowest point.
Claim 13
Dependent Claim 23 words
The particle agglutination analyzing plate according to claim, 11 wherein said lowest point of the inverted bottom surface of the vessel is flattened.
Claim 14
Dependent Claim 35 words
A plate according to claim 1, wherein said bottom surface has the shape of an inverted cone, and said plurality of steps are arranged concentrically and intermittently about the lowest point of the inverted cone.
Claim 15
Dependent Claim 18 words
A plate according to claim 1, wherein said plurality of steps are formed by a single spiral depression.
Claim 16
Dependent Claim 18 words
A plate according to claim 1, wherein said plurality of steps are formed by a single spiral protrusion.

References Cited (Backward Citations)

US3432275A Cited
US3656833A Cited
US3770380A Cited
US3773426A Cited
US4290997A Cited
US4303616A Cited
US4245052A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1987-08-21 1988-02-20 1988-08-21 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1991-08-21 1992-02-20 1992-08-21 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1995-08-21 1996-02-20 1996-08-21 $7700.00 Window Closed / Lapsed

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