US4465480A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Blood transfusion tubes and devices for use in contact with human blood
Assignee: Toyobo Co Ltd
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Filing: 1981-12-21
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Granted: 1984-08-14
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Expires: 2001-12-21
Abstract
Abstract Devices such as blood transfusion tubes, which can be contacted with human blood at reduced risk of blood clotting, made of a segmented polyether polyurethane urea obtained by chain extending an isocyanate-terminated prepolymer with a diamine having a branch at at least one α-carbon atom, such as 1,2-propylene diamine or 1,4-cyclohexylene diamine.
Inventors
- 👤 Masakazu Tanaka
- 👤 Ken Murayama
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 21:34
CPC Classifications
C; C08; C08G; C08G18/00; C08G18/06; C08G18/08; C08G18/10; A; A61; A61L; A61L33/00; A61L33/06; A61L33/068
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
145 words
A device for use in contact with human blood, consisting of or covered with a segmented polyether polyurethane urea obtained by chain-extension of an isocyanate-terminated prepolymer, said prepolymer being obtained by reacting a polyoxyalkylene diol having a molecular weight of from 650 to 3000 with a diisocyanate, said chain-extension being conducted with a diamine represented by the following formula (I) or/and a diamine represented by the following formula (II): ##STR3## wherein each of R 1 and R 2 is an alkyl group having 1 to 5 carbon atoms or one of R 1 and R 2 is a hydrogen atom and the other is an alkyl group having 1 to 5 carbon atoms, each of R 3 and R 4 is a hydrogen atom or an alkyl group having 1 to 5 carbon atoms, and n represents 0 or an integer from 1 to 4.
Claim 2
Independent Claim
145 words
A device for use in contact with human blood, consisting of or covered with a segmented polyether polyurethane urea obtained by chain-extension of an isocyanate-terminated prepolymer, said prepolymer being obtained by reacting a polyoxyalkylene diol having a molecular weight of from 650 to 3000 with a diisocyanate, said chain-extension being conducted with a diamine represented by the following formula (I) or/and a diamine represented by the following formula (II): ##STR3## wherein each of R 1 and R 2 is an alkyl group having 1 to 5 carbon atoms or one of R 1 and R 2 is a hydrogen atom and the other is an alkyl group having 1 to 5 carbon atoms, each of R 3 and R 4 is a hydrogen atom or an alkyl group having 1 to 5 carbon atoms, and n represents 0 or an integer from 1 to 4.
Claim 3
Dependent Claim
12 words
A device according to claim 1, which is a blood transfusion tube.
Claim 4
Dependent Claim
84 words
A device according to claim 1, wherein a polyoxyalkylene glycol, one terminal of which is blocked, represented by the following formula (III), exists in the prepolymer reaction stage in a quantity of from 0.2 to 10 mol %, based on the diisocyanate component: ##STR4## wherein R 5 is a hydrogen atom or methyl group, R 6 is an alkyl group having 1 to 20 carbon atoms, aralkyl group, phenyl group, or substituted phenyl group, and n is an integer of from 20 to 500.
Claim 5
Dependent Claim
12 words
A device according to claim 3, which is a blood transfusion tube.
Claim 6
Dependent Claim
24 words
A device according to claim 3, wherein the quantity of the polyoxyalkylene glycol is 0.5 to 7 mol % based on the diisocyanate component.
References Cited (Backward Citations)
US3822238A
Cited
JPS5016800A
Cited
US4173689A
Cited
US4049591A
Cited
US4131604A
Cited
US4255550A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-08-14 | 1988-02-13 | 1988-08-14 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-08-14 | 1992-02-13 | 1992-08-14 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-08-14 | 1996-02-13 | 1996-08-14 | $7700.00 | Window Closed / Lapsed |