Patent DE2506524C3 successfully refreshed from Google Patents.
Patent US6580124B1 successfully refreshed from Google Patents.
US4464362A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Topical skin repair composition
Assignee: Estee Lauder Inc
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Filing: 1981-06-26
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Granted: 1984-08-07
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Expires: 2001-06-26
Abstract
Abstract Cosmetic compositions containing an active substance complex for promoting the DNA repair process of the skin cells, in order to guard against possible cellular skin damage due to excessive light influence, and to counteract the light-caused aging process of the skin. The active substance complex consists of inactivated cultures of bacteria of the genus Bifidobacterium or bacteria related to this genus.
Inventors
- 👤 Martin Kludas
- 👤 Dieter Heise
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-29 04:50
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/96; A61K8/99; A61Q; A61Q19/00; A61Q19/004; A61Q19/08
Claims Analysis
Total Claims: 30
Claim 1
Independent Claim
76 words
Cosmetic compositions for topical application to a person's skin for promoting the repair of DNA in skin cells damaged by exposure to ultraviolet radiation, comprising a vehicle for topical application and a DNA repair capacity effective amount of an active substance complex which promotes the DNA repair process in skin cells, the active substance complex including inactivated cultures of bacteria selected from a genus of the group consisting of Bifidobacterium, Actinomycetaceae, Propionibacteriaceae, Lactobacillaceae and Coryneform bacteria.
Claim 2
Dependent Claim
76 words
Cosmetic compositions for topical application to a person's skin for promoting the repair of DNA in skin cells damaged by exposure to ultraviolet radiation, comprising a vehicle for topical application and a DNA repair capacity effective amount of an active substance complex which promotes the DNA repair process in skin cells, the active substance complex including inactivated cultures of bacteria selected from a genus of the group consisting of Bifidobacterium, Actinomycetaceae, Propionibacteriaceae, Lactobacillaceae and Coryneform bacteria.
Claim 3
Dependent Claim
31 words
The cosmetic composition of claim 1, wherein the active substance complex is present in an amount of at least about 5 weight percent, based on the total weight of the composition.
Claim 4
Dependent Claim
31 words
The cosmetic composition of claim 1, wherein the active substance complex is present in an amount between about 5 and 20 weight percent, based on the total weight of the composition.
Claim 5
Dependent Claim
52 words
A cosmetic composition for topical application to a person's skin for promoting the repair of DNA in skin cells damaged by exposure to ultraviolet radiation, comprising a vehicle for topical application and a DNA repair capacity effective amount of an active substance complex including inactivated cultures of bacteria of the genus Bifidobacterium.
Claim 6
Dependent Claim
52 words
A cosmetic composition for topical application to a person's skin for promoting the repair of DNA in skin cells damaged by exposure to ultraviolet radiation, comprising a vehicle for topical application and a DNA repair capacity effective amount of an active substance complex including inactivated cultures of bacteria of the genus Bifidobacterium.
Claim 7
Dependent Claim
31 words
The cosmetic composition of claim 4, wherein the active substance complex is present in an amount of at least about 5 weight percent, based on the total weight of the composition.
Claim 8
Dependent Claim
31 words
The cosmetic composition of claim 4, wherein the active substance complex is present in an amount between about 5 to 20 weight percent, based on the total weight of the composition.
Claim 9
Dependent Claim
54 words
A cosmetic composition for topical application to a person's skin for promoting the repair of DNA in skin cells damaged by exposure to ultraviolet radiation, comprising a vehicle for topical application and a DNA repair capacity effective amount of an active substance complex including inactivated cultures of bacteria of the species Bifidobacterium longum (Reuter).
Claim 10
Dependent Claim
54 words
A cosmetic composition for topical application to a person's skin for promoting the repair of DNA in skin cells damaged by exposure to ultraviolet radiation, comprising a vehicle for topical application and a DNA repair capacity effective amount of an active substance complex including inactivated cultures of bacteria of the species Bifidobacterium longum (Reuter).
Claim 11
Dependent Claim
31 words
The cosmetic composition of claim 7, wherein the active substance complex is present in an amount of at least about 5 weight percent, based on the total weight of the composition.
Claim 12
Dependent Claim
31 words
The cosmetic composition of claim 7, wherein the active substance complex is present in an amount between about 5 to 20 weight percent, based on the total weight of the composition.
Claim 13
Independent Claim
65 words
A method for promoting the repair of DNA of skin cells damaged by exposure to ultraviolet radiation, comprising applying to the skin a topical cosmetic composition including a vehicle for topical application and a DNA repair capacity effective amount of an active substance complex including inactivated cultures of bacteria of a genus selected from the group consisting of Bifidobacterium, Actinomycetaceae, Propionibacteriaceae, Lactobacillaceae and Coryneform bacteria.
Claim 14
Independent Claim
65 words
A method for promoting the repair of DNA of skin cells damaged by exposure to ultraviolet radiation, comprising applying to the skin a topical cosmetic composition including a vehicle for topical application and a DNA repair capacity effective amount of an active substance complex including inactivated cultures of bacteria of a genus selected from the group consisting of Bifidobacterium, Actinomycetaceae, Propionibacteriaceae, Lactobacillaceae and Coryneform bacteria.
Claim 15
Dependent Claim
29 words
The method of claim 10, wherein the active substance complex is present in amounts of at least about 5 weight percent, based on the total weight of the composition.
Claim 16
Independent Claim
54 words
A method for promoting the repair of DNA of skin cells damaged by exposure to ultraviolet radiation, comprising applying to the skin a topical cosmetic composition including a vehicle for topical application and a DNA repair capacity effective amount of an active substance complex including inactivated cultures of bacteria selected from the genus Bifidobacterium.
Claim 17
Independent Claim
54 words
A method for promoting the repair of DNA of skin cells damaged by exposure to ultraviolet radiation, comprising applying to the skin a topical cosmetic composition including a vehicle for topical application and a DNA repair capacity effective amount of an active substance complex including inactivated cultures of bacteria selected from the genus Bifidobacterium.
Claim 18
Dependent Claim
29 words
The method of claim 12, wherein the active substance complex is present in amounts of at least about 5 weight percent, based on the total weight of the composition.
Claim 19
Independent Claim
55 words
A method for promoting the repair of DNA of skin cells damaged by exposure to ultraviolet radiation, comprising applying to the skin a topical cosmetic composition including a vehicle for topical application and a DNA repair capacity effective amount of an active substance complex including inactivated cultures of bacteria of the species Bifidobacterium longum (Reuter).
Claim 20
Independent Claim
55 words
A method for promoting the repair of DNA of skin cells damaged by exposure to ultraviolet radiation, comprising applying to the skin a topical cosmetic composition including a vehicle for topical application and a DNA repair capacity effective amount of an active substance complex including inactivated cultures of bacteria of the species Bifidobacterium longum (Reuter).
Claim 21
Dependent Claim
30 words
The method of claim 14, wherein the active substance complex is present in an amount of at least about 5 weight percent, based on the total weight of the composition.
Claim 22
Independent Claim
70 words
A method of preparing an active substance complex for promoting the repair of DNA in skin cells damaged by exposure to ultraviolet radiation, comprising inactivating cells of an anaerobically obtained surface culture of bacteria selected from a genus of the group consisting of Bifidobacterium, Actinomycetaceae, Propionibacteriaceae, Lactobacillaceae and Coryneform bacteria said inactivating of cells being by the steps of rinsing, resuspending, and subjecting the cells to ultrasound or mechanical inactivation.
Claim 23
Independent Claim
70 words
A method of preparing an active substance complex for promoting the repair of DNA in skin cells damaged by exposure to ultraviolet radiation, comprising inactivating cells of an anaerobically obtained surface culture of bacteria selected from a genus of the group consisting of Bifidobacterium, Actinomycetaceae, Propionibacteriaceae, Lactobacillaceae and Coryneform bacteria said inactivating of cells being by the steps of rinsing, resuspending, and subjecting the cells to ultrasound or mechanical inactivation.
Claim 24
Dependent Claim
38 words
The method of claim 16, including the steps of rinsing the bacteria with physiological NaCl solution, centrifuging the rinsed bacteria, resuspending the bacteria in physiological NaCl solution and subjecting the bacteria to ultrasound while cooling to 0° C.
Claim 25
Dependent Claim
64 words
An active substance complex for accelerating the repair of DNA in a person's skin cells damaged by exposure to ultraviolet radiation by topical application to the person's skin, comprising inactivated bacteria of a genus selected from the group consisting of Bifidobacterium, Actinomycetaceae, Propionibacteriaceae, Lactobacillaceae and Coryneform bacteria said bacteria being inactivated by rinsing, resuspending, and subjecting the bacterial cell to ultrasound or mechanical inactivation.
Claim 26
Dependent Claim
64 words
An active substance complex for accelerating the repair of DNA in a person's skin cells damaged by exposure to ultraviolet radiation by topical application to the person's skin, comprising inactivated bacteria of a genus selected from the group consisting of Bifidobacterium, Actinomycetaceae, Propionibacteriaceae, Lactobacillaceae and Coryneform bacteria said bacteria being inactivated by rinsing, resuspending, and subjecting the bacterial cell to ultrasound or mechanical inactivation.
Claim 27
Dependent Claim
52 words
An active substance complex for accelerating the repair of DNA in a person's skin cells damaged by exposure to ultraviolet radiation by topical application to the person's skin, comprising inactivated bacteria of the genus Bifidobacterium said bacteria being inactivated by rinsing, resuspending, and subjecting the bacterial cell to ultrasound or mechanical inactivation.
Claim 28
Dependent Claim
52 words
An active substance complex for accelerating the repair of DNA in a person's skin cells damaged by exposure to ultraviolet radiation by topical application to the person's skin, comprising inactivated bacteria of the genus Bifidobacterium said bacteria being inactivated by rinsing, resuspending, and subjecting the bacterial cell to ultrasound or mechanical inactivation.
Claim 29
Dependent Claim
54 words
An active substance complex for accelerating the repair of DNA in a person's skin cells damaged by exposure to ultraviolet radiation by topical application to the person's skin, comprising inactivated bacteria of the species Bifidobacterium longum (Reuter) said bacteria being inactivated by rinsing, resuspending, and subjecting the bacterial cell to ultrasound or mechanical inactivation.
Claim 30
Dependent Claim
54 words
An active substance complex for accelerating the repair of DNA in a person's skin cells damaged by exposure to ultraviolet radiation by topical application to the person's skin, comprising inactivated bacteria of the species Bifidobacterium longum (Reuter) said bacteria being inactivated by rinsing, resuspending, and subjecting the bacterial cell to ultrasound or mechanical inactivation.
References Cited (Backward Citations)
GB468290A
Cited
FR1096421A
Cited
FR1112301A
Cited
FR1603826A
Cited
FR2052143A5
Cited
DE2164052A1
Cited
US4057627A
Cited
DE2617919A1
Cited
GB1545206A
Cited
DE2852779A1
Cited
GB2037160A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-08-07 | 1988-02-06 | 1988-08-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-08-07 | 1992-02-06 | 1992-08-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-08-07 | 1996-02-06 | 1996-08-07 | $7700.00 | Window Closed / Lapsed |