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US4459267A Expired / Lapsed US ⏱️ 0.0 years remaining

Pipette means

Assignee: University of Birmingham
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Filing: 1982-05-20
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Granted: 1984-07-10
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Expires: 2002-05-20
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Abstract

Abstract Pipette means having aspirating and expelling means and a substantially cylindrical tube connected to a pipette tip for fluid flow therebetween; the expelling means being arranged to apply pressure to the outer surface of the cylindrical tube, the diameter and wall thickness of which being chosen so that said tube is compressed elastically and substantially uniformly and circumferentially to reduce the internal volume thereof, tending to expel any liquid from the pipette tip; and the aspirating means being arranged to relieve pressure from the outer surface of said tube, allowing the tube to expand substantially circumferentially and uniformly so that liquid may thereby be drawn into the pipette tip.

Inventors

  • 👤 Roger A. Bunce
  • 👤 John E. C. Gibbons
  • 👤 Larry J. Kricka

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-09 03:34
CPC Classifications
B; B01; B01L; B01L3/00; B01L3/02; B01L3/021

Claims Analysis

Total Claims: 13
Claim 1
Independent Claim 226 words
Pipette means comprising: a flexible tube connected to a pipette tip for liquid flow therebetween, said tube being of substantially cylindrical, elastomeric form with a ratio of wall thickness to internal diameter not less than about 1:2 to maintain compression and expansion thereof substantially uniformly circumferential; expelling means arranged to apply pressure to the outside surface of said tube to compress said tube and reduce its internal volume tending to expel liquid from said pipette tip; and aspirating means arranged to relieve pressure from the outside surface of said tube to allow expansion of said tube and its internal volume so that liquid may be drawn into said pipette tip; and wherein said aspirating and expelling means includes a source of fluid pressure, a reservoir, and valve means operatively coupling said source and said reservoir, said valve means having a first position wherein pressure is removed from the cylindrical tube to aspirate a sample into the pipette tip while said reservoir is simultaneously charged with fluid pressure from said source, and a second position wherein pressure is applied to the cylindrical tube by applying said charged pressure in said reservoir to at least assist in expelling the sample from the pipette tip, said aspirating and expelling means thereby being operable by the application and relief respectively of said fluid pressure to and from said cylindrical tube.
Claim 2
Dependent Claim 226 words
Pipette means comprising: a flexible tube connected to a pipette tip for liquid flow therebetween, said tube being of substantially cylindrical, elastomeric form with a ratio of wall thickness to internal diameter not less than about 1:2 to maintain compression and expansion thereof substantially uniformly circumferential; expelling means arranged to apply pressure to the outside surface of said tube to compress said tube and reduce its internal volume tending to expel liquid from said pipette tip; and aspirating means arranged to relieve pressure from the outside surface of said tube to allow expansion of said tube and its internal volume so that liquid may be drawn into said pipette tip; and wherein said aspirating and expelling means includes a source of fluid pressure, a reservoir, and valve means operatively coupling said source and said reservoir, said valve means having a first position wherein pressure is removed from the cylindrical tube to aspirate a sample into the pipette tip while said reservoir is simultaneously charged with fluid pressure from said source, and a second position wherein pressure is applied to the cylindrical tube by applying said charged pressure in said reservoir to at least assist in expelling the sample from the pipette tip, said aspirating and expelling means thereby being operable by the application and relief respectively of said fluid pressure to and from said cylindrical tube.
Claim 3
Dependent Claim 19 words
Pipette means according to claim 1 in which the source of fluid pressure is a minature gas storage cylinder.
Claim 4
Dependent Claim 22 words
Pipette means according to claim 1 further including timing means arranged to control sequence and timing of operation of said valve means.
Claim 5
Dependent Claim 16 words
Pipette means according to claim 1 in which the cylindrical tube is made of latex rubber.
Claim 6
Dependent Claim 24 words
Pipette means according to claim 1 in which the cylindrical tube is made of latex rubber lined with a thin layer of silicone rubber.
Claim 7
Dependent Claim 22 words
Pipette means according to claim 1 in which the cylindrical tube is made of a mixture of silicone rubber and natural rubber.
Claim 8
Dependent Claim 23 words
Pipette means according to claim 1 further including rate control means for controlling the exhausting rate of fluid from around the cylindrical tube.
Claim 9
Dependent Claim 16 words
Pipette means according to claim 7 wherein said rate control means is an adjustable needle valve.
Claim 10
Dependent Claim 27 words
Pipette means according to claim 1 further including temperature control means for thermostatically controlling the temperature of said pipette means and of any fluids supplied to it.
Claim 11
Dependent Claim 40 words
Pipette means according to claim 1 wherein said source is a source of liquid pressure and wherein said aspirating and expelling means are operated by withdrawal and application of said liquid pressure at the outer surface of said cylindrical tube.
Claim 12
Dependent Claim 18 words
Pipette means according to claim 10 wherein said liquid pressure is provided by a pressurized reservoir of liquid.
Claim 13
Dependent Claim 40 words
Pipette means according to claim 1 wherein said source is a source of compressible fluid and wherein said aspirating and expelling means are operated by withdrawal and application of said compressible fluid at the outer surface of said cylindrical tube.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1987-07-10 1988-01-09 1988-07-10 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1991-07-10 1992-01-09 1992-07-10 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1995-07-10 1996-01-09 1996-07-10 $7700.00 Window Closed / Lapsed

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