Patent US4453927A successfully refreshed from Google Patents.
US4453927A
Expired / Lapsed
US
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Method and apparatus for microfiltration of blood
Assignee: MedChem Products Inc
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Filing: 1980-11-12
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Granted: 1984-06-12
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Expires: 2000-11-12
Abstract
Abstract A microfilter and method for infusion of blood and blood components into premature or neonatal infants designed to be utilized as an interruption filter between the syringe carrying the blood to be transfused and the needle injected into the vein of the patient or stopcock connections to the vasculature of the patient. The filter of this invention includes a filter body adapted to engage a syringe nipple and a needle hub, or standard luer taper fitting. The square body of this filter encases a stainless steel filter screen passing particles of less than 18 microns in diameter and restricting or trapping particles of larger diameter. The filter functions by a sieving or direct interruption of passage of larger microaggregates. The filter is specifically designed for utilization one time only. The method includes transfusing 5 to 20 cc of blood while screening out particles of less than 18 microns.
Inventors
- 👤 George E. Sinko
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 04:02
CPC Classifications
A; A61; A61M; A61M1/00; A61M1/36; A61M1/3621; A61M1/3627; A61M1/3633; A61M5/00; A61M5/178; A61M5/31; A61M5/3145; B; B01; B01D; B01D29/00; B01D29/01; B01D29/012; B01D29/05
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
212 words
A microfilter for infusing blood and blood components into infants and pediatric patients comprising: a filter body constructed from two plastic sections; the first section comprising a syringe adapter end; the second section comprising a needle adapter end; a woven filter screen retained between said syringe adapter end and said needle adapter end; said woven filter screen comprising a stainless steel cloth; said stainless steel cloth comprising a Dutch twill weave having a microaperture size of in the order of 18 microns effective to retain microaggregates 18 microns or larger in size and effective to pass particles, including viable components of blood such as erythrocytes, leukocytes, platelets, Factor VIII and Factor IX, in the order of 18 microns or smaller; said syringe adapter end and said needle adapter end being connected to form a filter body having a body opening constructed internal of said filter body and a multiplicity of screen support ribs internal of said filter body so positioned as to contact and support said filter screen; said filter screen being connected to and formed in the filter body in a composite integral structure by embedding the periphery of the filter screen in the two sections by sonic welding; and the volumetric capacity of the filter being less than 1 cc.
Claim 2
Dependent Claim
212 words
A microfilter for infusing blood and blood components into infants and pediatric patients comprising: a filter body constructed from two plastic sections; the first section comprising a syringe adapter end; the second section comprising a needle adapter end; a woven filter screen retained between said syringe adapter end and said needle adapter end; said woven filter screen comprising a stainless steel cloth; said stainless steel cloth comprising a Dutch twill weave having a microaperture size of in the order of 18 microns effective to retain microaggregates 18 microns or larger in size and effective to pass particles, including viable components of blood such as erythrocytes, leukocytes, platelets, Factor VIII and Factor IX, in the order of 18 microns or smaller; said syringe adapter end and said needle adapter end being connected to form a filter body having a body opening constructed internal of said filter body and a multiplicity of screen support ribs internal of said filter body so positioned as to contact and support said filter screen; said filter screen being connected to and formed in the filter body in a composite integral structure by embedding the periphery of the filter screen in the two sections by sonic welding; and the volumetric capacity of the filter being less than 1 cc.
Claim 3
Dependent Claim
71 words
The invention of claim 1 wherein: a. a multiplicity of said screen support rubs are constructed internal of said syringe adapter end; b. a multiplicity of said screen support ribs are constructed internal of said needle adapter end; c. the dimensioning and spacing of said assembled structure being such that the syringe end ribs and the needle end ribs are spaced a distance equivalent to the thickness of said filter screen.
Claim 4
Dependent Claim
26 words
The invention of claim 1 further comprising: `a. a syringe attached to said syringe adapter end, and b. a needle attached to said needle adapter end.
Claim 5
Dependent Claim
28 words
The invention of claim 1 further comprising: a. a syringe attached to said syringe adapter end, and b. a leur tapered fitting attached to said needle adapter end.
Claim 6
Dependent Claim
12 words
The invention of claim 1, wherein: the volumetric capacity is 0.07-0.08 cc.
Claim 7
Independent Claim
177 words
A method of infusing blood and blood components in infants and neonates comprising the steps of: removing microaggregates having a particle size greater than in the order of 18 microns from a predetermined quantity of blood and blood components while passing particle sizes including viable components of blood such as erythrocytes, leukocytes, platelets, Factor VIII and Factor IX, in the order of 18 microns or smaller; injecting the blood and blood components including viable components of blood such as erythrocytes, leukocytes, platelets, Factor VIII and Factor IX, having a particle size in the order of 18 microns or smaller into the infant or neonate; the step of removing including passing the blood through a filter having a stainless steel screen with a Dutch twill weave; the step of passing blood and blood components through the filter includes priming the filter with in the order of 1 cc of blood and blood components; and the step of injecting includes injecting in the order of 5 to 20 cc of blood and blood components into the infant or neonate.
Claim 8
Independent Claim
177 words
A method of infusing blood and blood components in infants and neonates comprising the steps of: removing microaggregates having a particle size greater than in the order of 18 microns from a predetermined quantity of blood and blood components while passing particle sizes including viable components of blood such as erythrocytes, leukocytes, platelets, Factor VIII and Factor IX, in the order of 18 microns or smaller; injecting the blood and blood components including viable components of blood such as erythrocytes, leukocytes, platelets, Factor VIII and Factor IX, having a particle size in the order of 18 microns or smaller into the infant or neonate; the step of removing including passing the blood through a filter having a stainless steel screen with a Dutch twill weave; the step of passing blood and blood components through the filter includes priming the filter with in the order of 1 cc of blood and blood components; and the step of injecting includes injecting in the order of 5 to 20 cc of blood and blood components into the infant or neonate.
Claim 9
Dependent Claim
24 words
The method of claim 6 wherein: the step of passing the blood through the filter includes priming the filter with 0.07-0.08 cc of blood.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-06-12 | 1987-12-12 | 1988-06-12 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-06-12 | 1991-12-12 | 1992-06-12 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-06-12 | 1995-12-12 | 1996-06-12 | $7700.00 | Window Closed / Lapsed |