Substituted 8-phenylxanthines

Claim 1

A compound having the structural formula ##STR16## wherein R and R 1 may be the same or different and are hydrogen, alkyl of from one to six carbon atoms, hydroxyalkyl of from two to six carbon atoms, (CH 2 ) 2-4 N(R 3 ) 2 wherein R 3 is alkyl of from one to six carbon atoms, Ph(CH 2 ) 1-3 or CF 3 (CH 21-4; the dashed lines mean that the two substituents may only be in the three or four positions; X is hydrogen, halogen, hydroxy, alkyl of from one to six carbon atoms, or NR 4 R 5 wherein R 4 and R 5 are hydrogen or alkyl of from one to six carbon atoms, Y is NR 6 R 7 wherein R 6 is hydrogen, hydroxyalkyl of from two to six carbon atoms or alkyl of from one to six carbon atoms, R 7 is hydrogen, alkyl of from one to six carbon atoms, or (CH 2 ) 2-6 -NR 8 R 9 wherein R 8 and R 9 are hydrogen, alkyl of from one to six carbon atoms or when taken together form ##STR17## wherein m and n may be the same or different and are 1, 2, or 3 provided that the sum of m and n is an integer of from three to six and Z is a direct bond, O, S--(O) k wherein k is 0, 1, or 2 or N-R 10 wherein R 10 is hydrogen or alkyl of from one to six carbon atoms; or R 6 and R 7 when taken together form ##STR18##