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US4437192A
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Implants of biologically active glass or glass ceramic containing titania
Assignee: Nikon Corp
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Filing: 1983-03-16
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Granted: 1984-03-20
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Expires: 2003-03-16
Abstract
Abstract A biologically active glass and class-ceramic composition useful for making surgical and dental implants comprising, by mol %,: -SiO2 35 DIFFERENCE 60 -B2O3 5 DIFFERENCE 15 -Na2O 10 DIFFERENCE 30 -CaO 5 DIFFERENCE 40 -TiO2 0.5 DIFFERENCE 10 -P2O5 0 DIFFERENCE 15 -K2O 0 DIFFERENCE 20 -Li2O 0 DIFFERENCE 10 -MgO 0 DIFFERENCE 5 -Al2O3 + ZrO2 + Nb2O5 0 DIFFERENCE 8 -La2O3 + Ta2O5 + Y2O3 0 DIFFERENCE 8 and -F2 0 DIFFERENCE 15. -
Inventors
- 👤 Takamitsu Fujiu
- 👤 Makoto Ogino
- 👤 Michio Kariya
- 👤 Takeo Ichimura
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 05:08
CPC Classifications
C; C03; C03C; C03C3/00; C03C3/04; C03C3/076; C03C3/089; A; A61; A61L; A61L27/00; A61L27/02; A61L27/10; A61L27/12; C03C10/00; C03C10/0009; C03C10/0054; C03C4/00; C03C4/0007; A61F; A61F2310/00; A61F2310/00005; A61F2310/00179; A61F2310/00293
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
158 words
An improved implant comprising a biocompatible metal core coated with a layer of a biologically active glass or glass-ceramic having a composition consisting essentially of by mol%: ______________________________________
SiO.sub.2 40-60
B.sub.2 O.sub.3 8-15
Na.sub.2 O 15-30
CaO 8-30
P.sub.2 O.sub.5 0-8
K.sub.2 O 0-20
Li.sub.2 O 0-10
MgO 0-5
Al.sub.2 O.sub.3 + ZrO.sub.2 + Nb.sub.2 O.sub.5
0-8
La.sub.2 O.sub.3 + Ta.sub.2 O.sub.5 + Y.sub.2 O.sub.3
0-8 and
F.sub.2 0-15
______________________________________ the glass or glass-ceramic having substantially the same thermal expansion coefficient as that of the metal core, wherein the improvement comprises adding TiO 2 in an amount from 0.5 to 3 mole% to make up a total of 100 mol% glass composition to regulate the degree of biological activity of the glass or glass-ceramic represented by a saturated pH-value at the time when the glass or glass-ceramic is immersed in a simulated physiolgical solution, with no substantial change of the thermal expansion coefficient of the glass or glass-ceramic.
Claim 2
Dependent Claim
158 words
An improved implant comprising a biocompatible metal core coated with a layer of a biologically active glass or glass-ceramic having a composition consisting essentially of by mol%: ______________________________________
SiO.sub.2 40-60
B.sub.2 O.sub.3 8-15
Na.sub.2 O 15-30
CaO 8-30
P.sub.2 O.sub.5 0-8
K.sub.2 O 0-20
Li.sub.2 O 0-10
MgO 0-5
Al.sub.2 O.sub.3 + ZrO.sub.2 + Nb.sub.2 O.sub.5
0-8
La.sub.2 O.sub.3 + Ta.sub.2 O.sub.5 + Y.sub.2 O.sub.3
0-8 and
F.sub.2 0-15
______________________________________ the glass or glass-ceramic having substantially the same thermal expansion coefficient as that of the metal core, wherein the improvement comprises adding TiO 2 in an amount from 0.5 to 3 mole% to make up a total of 100 mol% glass composition to regulate the degree of biological activity of the glass or glass-ceramic represented by a saturated pH-value at the time when the glass or glass-ceramic is immersed in a simulated physiolgical solution, with no substantial change of the thermal expansion coefficient of the glass or glass-ceramic.
Claim 3
Dependent Claim
18 words
The implant of claim 1 wherein said TiO 2 is added in amounts from 0.5 to 1 mol%.
Claim 4
Dependent Claim
22 words
An implant as set forth in claim 1, wherein said coating layer of biologically active composition is 0.1 to 2 mm thick.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-03-20 | 1987-09-19 | 1988-03-20 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-03-20 | 1991-09-19 | 1992-03-20 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-03-20 | 1995-09-19 | 1996-03-20 | $7700.00 | Window Closed / Lapsed |