Pyridinyl substituted benzimidazoles and quinoxalines

Claim 1

A compound of the formula I or II wherein Z 1 is (a) 4-pyridinyl, (b) 3-pyridinyl, or (c) 3-pyridinyl substituted by (C 1 -C 4 )alkyl; wherein X 1 is (a) --(CH 2 ) n-- , (b) --O--, (c) --CH 2 --O--, or (d) --O--CH 2 --; wherein Y 1 is --(CH 2 ) m --R 7 ; wherein R 1 is hydrogen, a pharmacologically acceptable cation, (C 1 -C 12 ) alkyl, (C 3 -C 10 ) cycloalkyl, (C 7 -C 12 ) aralkyl, phenyl, phenyl mono-, di-, or trisubstituted by chloro, or (C 1 -C 3 ) alkyl, or phenyl para-substituted by (a) --NHCO--R 25 , (b) --O--CO--R 26 , (c) --CO--R 24 , (d) --O--CO--(p--Ph)--R 27 , or (e) --CH═N--NH--CO--NH 2 , wherein R 24 is phenyl or acetamidophenyl, R 25 is methyl, phenyl, acetamidophenyl, benzamidophenyl, or amino, R 26 is methyl, phenyl, amino or methoxy; and R 27 is hydrogen or acetamido, and wherein --(p--Ph) is 1,4-phenylene; wherein R 7 is (a) --CH 2 OH, (b) --CHO, or (c) --COOR 1 ; wherein m is an integer of from 0 to 4; and n is an integer of from 1 to 3, inclusive; including, pharmacologically acceptable acid addition salts thereof, and tautomeric forms thereof.