Patent US1592344A successfully refreshed from Google Patents.
Patent US4430324A successfully refreshed from Google Patents.
US4430324A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Ammonium fluorometallate containing compositions
Assignee: CPPD Inc A CORP OF
•
Filing: 1982-09-07
•
Granted: 1984-02-07
•
Expires: 2002-09-07
Abstract
Abstract The present invention discloses a composition, comprising: (i) an amount of ammonium fluorometallate effective to treat, control or substantially prevent oral problems, diseases or conditions; and (ii) a carrier for said fluorometallate suitable for use in the oral cavity. It also discloses a method for treating, controlling or substantially preventing oral problems, diseases or conditions which consists essentially of contacting dental tissues, surfaces or oral cavity with ammonium fluorometallate or a preparation thereof including nonfluoro ammonium metallate.
Inventors
- 👤 John P. Viccaro
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-29 10:52
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/19; A61K8/20; A61K8/21; A61Q; A61Q11/00
Claims Analysis
Total Claims: 25
Claim 1
Independent Claim
89 words
A composition, comprising: (i) an amount of ammonium fluorometallate selected from the group consisting of ZnNH 4 F 3 , CoNH 4 F 3 , CuNH 4 F 3 , Sn(NH 4 ) 2 F 6 , MnNH 4 F 3 , FeNH 4 F 3 , Zr(NH 4 ) 3 F 7 , In(NH 4 ) 3 F 6 and mixtures thereof, effective to treat, control or substantially prevent plaque formation and dental caries; and (ii) a carrier for said fluorometallate suitable for use in the oral cavity.
Claim 2
Dependent Claim
89 words
A composition, comprising: (i) an amount of ammonium fluorometallate selected from the group consisting of ZnNH 4 F 3 , CoNH 4 F 3 , CuNH 4 F 3 , Sn(NH 4 ) 2 F 6 , MnNH 4 F 3 , FeNH 4 F 3 , Zr(NH 4 ) 3 F 7 , In(NH 4 ) 3 F 6 and mixtures thereof, effective to treat, control or substantially prevent plaque formation and dental caries; and (ii) a carrier for said fluorometallate suitable for use in the oral cavity.
Claim 3
Dependent Claim
39 words
A substantially stable, anticariogenic composition according to claim 1 comprising as an active ingredient an amount of an ammonium fluorometallate in admixture with an acceptable oral medium compatible with said fluorometallate, said amount being effective to control dental caries.
Claim 4
Dependent Claim
47 words
A substantially stable, non-toxic composition for controlling plaque according to claim 1 comprising as an active ingredient an amount of an ammonium fluorometallate in admixture with an acceptable oral medium compatible with said fluorometallate, said amount being effective to control said plaque at the site of formation.
Claim 5
Dependent Claim
24 words
A composition as defined in claim 1, 2 or 3 wherein the amount of said fluorometallate is about 0.01% to about 3% by weight.
Claim 6
Dependent Claim
32 words
A composition as defined in claim 1, 2 or 3 wherein said ammonium fluorometallate is present in an effective amount up to an equivalent of about 1000 ppm of available fluoride ion.
Claim 7
Dependent Claim
21 words
A composition according to claim 1 wherein said amount of said Zn or Co ammonium fluorometallates have 100% fluoride ion availability.
Claim 8
Dependent Claim
78 words
A composition according to claim 1 wherein said ammonium fluorometallate is mixed with nonfluoro ammonium metallate selected from the group consisting of ZnNH 4 Cl 3 , CoNH 4 Cl 3 , Sn(NH 4 ) 2 Cl 6 , Al(NH 4 )Cl 4 , Zn(NH 4 ) 2 (SO 4 ) 2 , Co(NH 4 ) 2 (SO 4 ) 2 , Sn(NH 4 ) 2 (SO 4 ) 3 and Al(NH 4 )(SO 4 ) 2 .
Claim 9
Dependent Claim
21 words
A composition according to claim 1, 2 or 3 wherein said ammonium fluorometallate is a solid at normal temperature and pressure.
Claim 10
Dependent Claim
35 words
A composition according to claim 1, 2 or 3 wherein said composition is less astringent and metallic tasting than corresponding uncomplexed fluoride salts at equimolar concentrations such as cobalt fluoride, zinc fluoride or tin fluoride.
Claim 11
Dependent Claim
36 words
A composition according to claim 1, 2 or 3 which is in the form of a toothpaste wherein the ammonium fluorometallate is present in an effective amount up to about 1000 ppm of available fluoride ion.
Claim 12
Dependent Claim
36 words
A composition according to claim 1, 2 or 3 which is in the form of a mouthwash wherein the ammonium fluorometallate is present in an effective amount up to about 1000 ppm of available fluoride ion.
Claim 13
Independent Claim
96 words
A method for treating, controlling or substantially preventing plaque formation and dental caries which comprises applying to the site thereof a composition containing an amount of an ammonium fluorometallate selected from the group consisting of ZnNH 4 F 3 , CoNH 4 F 3 , CuNH 4 F 3 , Sn(NH 4 ) 2 F 6 , MnNH 4 F 3 , FeNH 4 F 3 , Zr(NH 4 ) 3 F 7 , In(NH 4 ) 3 F 6 and mixtures thereof, effective to control, treat or substantially prevent said oral problems, diseases or conditions.
Claim 14
Independent Claim
96 words
A method for treating, controlling or substantially preventing plaque formation and dental caries which comprises applying to the site thereof a composition containing an amount of an ammonium fluorometallate selected from the group consisting of ZnNH 4 F 3 , CoNH 4 F 3 , CuNH 4 F 3 , Sn(NH 4 ) 2 F 6 , MnNH 4 F 3 , FeNH 4 F 3 , Zr(NH 4 ) 3 F 7 , In(NH 4 ) 3 F 6 and mixtures thereof, effective to control, treat or substantially prevent said oral problems, diseases or conditions.
Claim 15
Independent Claim
37 words
A method for controlling, treating or substantially preventing dental caries which comprises applying to the site of formation of said dental caries an oral composition containing an effective amount of an ammonium fluorometallate whereby cariogenicity is controlled.
Claim 16
Independent Claim
37 words
A method for controlling, treating or substantially preventing dental caries which comprises applying to the site of formation of said dental caries an oral composition containing an effective amount of an ammonium fluorometallate whereby cariogenicity is controlled.
Claim 17
Dependent Claim
35 words
A method for controlling plaque formation according to claim 12 comprising applying to the site of said plaque formation a composition comprising an effective amount of an ammonium fluorometallate whereby said plaque formation is controlled.
Claim 18
Dependent Claim
23 words
A method according to claim 12, 13 or 14 wherein the amount of said fluorometallate is about 0.01% to about 3% by weight.
Claim 19
Dependent Claim
28 words
A method according to claim 12, 13 or 14 wherein said ammonium fluorometallate is present in an effective amount up to about 1000 ppm of available fluoride ion.
Claim 20
Dependent Claim
21 words
A method according to claim 12 wherein said amount of said Zn or Co ammonium fluorometallates have 100% fluoride ion availability.
Claim 21
Dependent Claim
78 words
A method according to claim 12 wherein said ammonium fluorometallate is mixed with nonfluoro ammonium metallate selected from the group consisting of ZnNH 4 Cl 3 , CoNH 4 Cl 3 , Sn(NH 4 ) 2 Cl 6 , Al(NH 4 )Cl 4 , Zn(NH 4 ) 2 (SO 4 ) 2 , Co(NH 4 ) 2 (SO 4 ) 2 , Sn(NH 4 ) 2 (SO 4 ) 3 and Al(NH 4 )(SO 4 ) 2 .
Claim 22
Dependent Claim
21 words
A method according to claim 12, 13 or 14 wherein said ammonium fluorometallate is a solid at normal temperature and pressure.
Claim 23
Dependent Claim
35 words
A method according to claim 12, 13 or 14 wherein said composition is less astringent and metallic tasting than corresponding uncomplexed fluoride salts at equimolar concentrations such as cobalt fluoride, zinc fluoride or tin fluoride.
Claim 24
Dependent Claim
38 words
A method according to claim 12, 13 or 14 wherein said composition is in the form of a toothpaste wherein the ammonium fluorometallate is present in an effective amount up to about 1000 ppm of available fluoride ion.
Claim 25
Dependent Claim
38 words
A method according to claim 12, 13 or 14 wherein said composition is in the form of a mouthwash wherein the ammonium fluorometallate is present in an effective amount up to about 1000 ppm of available fluoride ion.
References Cited (Backward Citations)
US3201316A
Cited
US3490866A
Cited
GB1188914A
Cited
GB1288892A
Cited
US3937804A
Cited
GB2077281A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-02-06 | 1987-08-08 | 1988-02-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-02-06 | 1991-08-08 | 1992-02-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-02-06 | 1995-08-08 | 1996-02-07 | $7700.00 | Window Closed / Lapsed |