US4428932A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Pharmaceutical compositions
Assignee: Beecham Group PLC
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Filing: 1982-04-29
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Granted: 1984-01-31
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Expires: 2002-04-29
Abstract
Abstract A pharmaceutical composition, for use in the desensitization therapy of humans allergic to non-infective allergens, comprises a non-infective allergen and an adjuvant consisting of a C10-22 alkyl ester of tyrosine or a pharmaceutically acceptable salt thereof.
Inventors
- 👤 Brain G. Overell
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 22:05
CPC Classifications
A; A61; A61K; A61K39/00; A61K39/35; A61K39/36; A61P; A61P37/00; A61P37/08; A61K2039/555; A61K2039/55511
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
30 words
A pharmaceutical composition comprising a desensitizing effective amount of a non-infective allergen and an adjuvant effective amount of C 10-22 alkyl ester of tyrosine or a pharmaceutically acceptable salt thereof.
Claim 2
Dependent Claim
30 words
A pharmaceutical composition comprising a desensitizing effective amount of a non-infective allergen and an adjuvant effective amount of C 10-22 alkyl ester of tyrosine or a pharmaceutically acceptable salt thereof.
Claim 3
Dependent Claim
23 words
A composition according to claim 1, in which the alkyl ester is the n-decyl, n-dodecyl, n-tetradecyl, n-hexadecyl, n-octadecyl or n-eicosyl ester of tyrosine.
Claim 4
Dependent Claim
23 words
A composition according to claim 1, in which the non-infective allergen is selected from pollens, weeds, house dust mites, dander and Hymeroptera venoms.
Claim 5
Dependent Claim
13 words
A composition according to claim 1, comprising a non-infective allergen and n-octadecyl tyrosine.
Claim 6
Dependent Claim
14 words
A composition according to claim 1, in which the allergen is rye grass pollen.
Claim 7
Dependent Claim
16 words
A composition according to claim 1, in the form of a desensitisation vaccine for allergic humans.
Claim 8
Dependent Claim
26 words
A process for the preparation of a composition according to claim 1, which comprises bringing into conjunction the allergen and the tyrosine ester or salt thereof.
Claim 9
Dependent Claim
26 words
A method of treating allergy, which comprises administering to the sufferer an amount effective for desensitisation to non-infective allergen of a composition according to claim 1.
References Cited (Backward Citations)
US3761585A
Cited
US4258029A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-01-30 | 1987-08-01 | 1988-01-31 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-01-30 | 1991-08-01 | 1992-01-31 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-01-30 | 1995-08-01 | 1996-01-31 | $7700.00 | Window Closed / Lapsed |