US4424210A
Expired / Lapsed
US
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Vehicle composition containing 1-substituted azacycloalkan-2-ones
Assignee: Whitby Research Inc
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Filing: 1981-12-07
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Granted: 1984-01-03
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Expires: 2001-12-07
Abstract
Abstract Compositions useful for carrying physiologically active agents such as therapeutic agents through skin and other body membranes comprising the agent and an effective, non-toxic amount of a compound having the structural formula ##STR1## wherein R' is H or a lower alkyl group, m is 3-7, N is 0-17 and R is --CH 3 , phenyl or substituted phenyl or ##STR2## with the proviso that if m is 3 and R is --CH 3 , then n is not 0-6.
Inventors
- 👤 Vithal J. Rajadhyaksha
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 19:19
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0014; A61K47/00; A61K47/06; A61K47/22; A61K8/00; A61K8/18; A61K8/30; A61K8/49; A61K8/4906; A61Q; A61Q17/00; A61Q17/005; A61Q19/00; A61Q17/02; A61Q17/04
Claims Analysis
Total Claims: 18
Claim 1
Independent Claim
53 words
A composition comprising an effective amount of a physiologiclly active agent and a non-toxic, effective penetrating amount of compound having the structural formula ##STR31## wherein R' is H or a lower alkyl group having 1-4 carbon atoms, n is 0-17 and R is --CH 3 , ##STR32## wherein R" is H or halogen.
Claim 2
Dependent Claim
53 words
A composition comprising an effective amount of a physiologiclly active agent and a non-toxic, effective penetrating amount of compound having the structural formula ##STR31## wherein R' is H or a lower alkyl group having 1-4 carbon atoms, n is 0-17 and R is --CH 3 , ##STR32## wherein R" is H or halogen.
Claim 3
Dependent Claim
14 words
The composition of claim 1 wherein the physiologically active agent is an antibacterial agent.
Claim 4
Dependent Claim
12 words
The composition of claim 2, wherein the antibacterial agent is an antibiotic.
Claim 5
Dependent Claim
23 words
The composition of claim 3 wherein the antibiotic is selected from the group consisting of lincomycin, clindamycin, erythromycin and pharmaceutically useful salts thereof.
Claim 6
Dependent Claim
15 words
The composition of claim 1 wherein the physiologically active agent is a physiologically active steroid.
Claim 7
Dependent Claim
14 words
The composition of claim 1 wherein the physiologically active agent is an antifungal agent.
Claim 8
Dependent Claim
12 words
The composition of claim 1 wherein the physiologically active agent is iododeoxyuridine.
Claim 9
Dependent Claim
12 words
The composition of claim 1 wherein the physiologically active agent is 5-fluorouracil.
Claim 10
Dependent Claim
42 words
A composition useful for topically administering a physiologically active agent to a human or animal comprising an effective amount of a physiologically active agent and a non-toxic, effective penetrating amount of a compound having the structural formula ##STR33## wherein n is 0-11.
Claim 11
Dependent Claim
42 words
A composition useful for topically administering a physiologically active agent to a human or animal comprising an effective amount of a physiologically active agent and a non-toxic, effective penetrating amount of a compound having the structural formula ##STR33## wherein n is 0-11.
Claim 12
Dependent Claim
14 words
The composition of claim 9 wherein the physiologically active agent is an antibacterial agent.
Claim 13
Dependent Claim
12 words
The composition of claim 9 wherein the antibacterial agent is an antibiotic.
Claim 14
Dependent Claim
23 words
The composition of claim 11 wherein the antibiotic is selected from the group consisting of lincomycin, clindamycin, erthromycin and pharmaceutically useful salts thereof.
Claim 15
Dependent Claim
15 words
The composition of claim 9 wherein the physiologically active agent is a physiologically active steroid.
Claim 16
Dependent Claim
14 words
The composition of claim 9 wherein the physiologically active agent is an antifungal agent.
Claim 17
Dependent Claim
12 words
The composition of claim 9 wherein the physiologically active agent is iododeoxyuridine.
Claim 18
Dependent Claim
12 words
The composition of claim 9 wherein the physiologically active agent is 5-fluorouracil.
References Cited (Backward Citations)
US3332938A
Cited
US3551554A
Cited
US3891757A
Cited
US3989816A
Cited
US3991203A
Cited
US4316893A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-01-02 | 1987-07-04 | 1988-01-03 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-01-02 | 1991-07-04 | 1992-01-03 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-01-02 | 1995-07-04 | 1996-01-03 | $7700.00 | Window Closed / Lapsed |